BRENDA - Enzyme Database show
show all sequences of 1.1.1.87

PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells

Szamtari, I.; Pap, A.; Rhl, R.; Ma, J.X.; Illarinonv, P.A.; Besra, G.S.; Rajnavolgyi, E.; Dezso, B.; Nagy, L.; J. Exp. Med. 203, 2351-2362 (2006)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
additional information
Homo sapiens
activation of peroxisome proliferator-activated receptor gamma induces the expression of RDH10
?
-
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Homo sapiens
Q8IZV5
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
dendritic cell
-
Homo sapiens
-
monocyte
-
Homo sapiens
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
activation of peroxisome proliferator-activated receptor gamma induces the expression of RDH10
669670
Homo sapiens
?
-
-
-
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
additional information
Homo sapiens
activation of peroxisome proliferator-activated receptor gamma induces the expression of RDH10
?
-
-
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
dendritic cell
-
Homo sapiens
-
monocyte
-
Homo sapiens
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
activation of peroxisome proliferator-activated receptor gamma induces the expression of RDH10
669670
Homo sapiens
?
-
-
-
-
Other publictions for EC 1.1.1.87
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
722303
Gabriel
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6
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692705
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RDH10 has 11-cis-retinol dehyd ...
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Thiahomoisocitrate: a highly p ...
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3
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1
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9
1
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Dynamic expression of the reti ...
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696220
Lin
Potassium is an activator of h ...
Saccharomyces cerevisiae
Biochemistry
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5
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1
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1
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1
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1
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1
3
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1
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3
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1
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1
1
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667934
Yamamoto
Substrate specificity analysis ...
Deinococcus radiodurans, Saccharomyces cerevisiae
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1
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24
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2
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20
2
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2
9
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1
2
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11
9
20
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2
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1
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2
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24
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2
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20
2
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686287
Cammas
Expression of the murine retin ...
Mus musculus
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236
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2007
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686950
Sandell
RDH10 is essential for synthes ...
Mus musculus
Genes Dev.
21
1113-1124
2007
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669670
Szamtari
PPARgamma controls CD1d expres ...
Homo sapiens
J. Exp. Med.
203
2351-2362
2006
-
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1
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660907
Miyazaki
Bifunctional isocitrate-homois ...
Pyrococcus horikoshii
Biochem. Biophys. Res. Commun.
331
341-346
2005
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1
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2
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1
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1
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2
1
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1
1
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1
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4
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1
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1
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4
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1
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2
1
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Miyazaki
Identification of a novel trif ...
Deinococcus radiodurans
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3
1
1
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7
1
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1
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4
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7
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2
2
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1
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3
1
1
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7
1
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669109
Miyazaki
Crystal structure of tetrameri ...
Thermus thermophilus
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6779-6788
2005
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1
1
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2
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1
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1
1
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1
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1
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3
1
1
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2
1
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656127
Miyazaki
Characterization of homoisocit ...
Thermus thermophilus
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1
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1
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1
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3
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1
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2
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4
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2
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1
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1
1
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1
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1
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2
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4
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2
2
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692332
Picozzi
Genomic organization and trans ...
Homo sapiens
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554
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2003
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Wu
Cloning and characterization o ...
Bos taurus, Homo sapiens, Mus musculus
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3
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12
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644538
Garrad
Lysine biosynthesis in selecte ...
Aspergillus fumigatus, Candida albicans, Cryptococcus neoformans, Saccharomyces cerevisiae
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1992
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Ye
Lysine biosynthesis pathway an ...
Schizosaccharomyces pombe
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1988
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644540
Gaillardin
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Saccharomycopsis lipolytica
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1982
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2
3
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3
1
1
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3
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1
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1
2
2
2
1
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2
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2
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1
1
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2
2
2
1
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644541
Broquist
-
Homoisocitric Dehydrogenase ...
Saccharomyces cerevisiae
Methods Enzymol.
17B
118-119
1971
-
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1
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1
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1
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1
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1
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1
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1
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1
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644539
Rowley
Homoisocitric dehydrogenase fr ...
Saccharomyces cerevisiae
Arch. Biochem. Biophys.
141
499-510
1970
2
-
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-
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1
4
-
3
1
1
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2
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1
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1
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3
-
1
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2
2
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2
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2
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2
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1
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4
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3
1
1
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1
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1
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3
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1
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2
2
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644543
Strassmann
Enzymatic formation of alpha-k ...
Saccharomyces cerevisiae
J. Biol. Chem.
240
4357-4361
1965
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