Protein Variants | Comment | Organism |
---|---|---|
A172L | the mutant shows improved thermal stability compared to the wild type enzyme | Thermus thermophilus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(2R,3S)-3-isopropylmalate + NAD+ | Thermus thermophilus | - |
(2S)-2-isopropyl-3-oxosuccinate + NADH + H+ | - |
? | |
(2R,3S)-3-isopropylmalate + NAD+ | Thermus thermophilus HB8 / ATCC 27634 / DSM 579 | - |
(2S)-2-isopropyl-3-oxosuccinate + NADH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermus thermophilus | Q5SIY4 | - |
- |
Thermus thermophilus HB8 / ATCC 27634 / DSM 579 | Q5SIY4 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(2R,3S)-3-isopropylmalate + NAD+ | - |
Thermus thermophilus | (2S)-2-isopropyl-3-oxosuccinate + NADH + H+ | - |
? | |
(2R,3S)-3-isopropylmalate + NAD+ | - |
Thermus thermophilus HB8 / ATCC 27634 / DSM 579 | (2S)-2-isopropyl-3-oxosuccinate + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IPMDH | - |
Thermus thermophilus |
isopropylmalate dehydrogenase | - |
Thermus thermophilus |
leuB | - |
Thermus thermophilus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Thermus thermophilus |