BRENDA - Enzyme Database show
show all sequences of 1.1.1.85

Amino acid residues that determine functional specificity of NADP- and NAD-dependent isocitrate and isopropylmalate dehydrogenases

Kalinina, O.V.; Gelfand, M.S.; Proteins 64, 1001-1009 (2006)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Acidithiobacillus ferrooxidans
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Agrobacterium tumefaciens
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Arthrospira platensis
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Aspergillus niger
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Azotobacter vinelandii
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Bacteroides fragilis
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Brassica napus
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Candida boidinii
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Candida maltosa
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Clostridium pasteurianum
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Cyberlindnera jadinii
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Eremothecium gossypii
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Escherichia coli
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Leptospira interrogans
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Mycobacterium bovis
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Ogataea angusta
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Saccharomyces cerevisiae
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Salmonella enterica subsp. enterica serovar Typhimurium
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Scheffersomyces stipitis
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Thermus aquaticus
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Zymoseptoria tritici
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview; phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Thermus thermophilus
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Acidithiobacillus ferrooxidans
Q56268
gene leuB
-
Agrobacterium tumefaciens
P24404
gene leuB
-
Arthrospira platensis
Q00412
-
-
Aspergillus niger
P87256
gene leu2A
-
Azotobacter vinelandii
P96197
-
-
Bacteroides fragilis
P54354
gene leuB
-
Brassica napus
P29102
-
-
Candida boidinii
Q01987
gene leu2
-
Candida maltosa
P07139
gene leu2
-
Clostridium pasteurianum
P31958
-
-
Cyberlindnera jadinii
P08791
gene leu2
-
Eremothecium gossypii
O60027
i.e. Eremothecium gossypii, gene leu2
-
Escherichia coli
P30125
gene leuB
-
Leptospira interrogans
P24015
gene leuB
-
Mycobacterium bovis
P94929
gene leuB
-
Ogataea angusta
P34733
gene leu2
-
Saccharomyces cerevisiae
P87267
orf Ydr417C
-
Salmonella enterica subsp. enterica serovar Typhimurium
P37412
gene leuB
-
Scheffersomyces stipitis
O94114
gene leu2
-
Thermus aquaticus
P24098
gene leuB
-
Thermus thermophilus
P61494
strain HB27, gene leuB
-
Thermus thermophilus
P61495
gene leuB
-
Zymoseptoria tritici
Q9Y897
i.e. Septoria tritici, gene leuC
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
substrate specificity-determining residues, e.g. L103, T105, A337, and T341, overview
670847
Escherichia coli
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Thermus thermophilus
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Leptospira interrogans
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Salmonella enterica subsp. enterica serovar Typhimurium
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Clostridium pasteurianum
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Bacteroides fragilis
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Brassica napus
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Arthrospira platensis
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Acidithiobacillus ferrooxidans
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Azotobacter vinelandii
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Agrobacterium tumefaciens
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Saccharomyces cerevisiae
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Aspergillus niger
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Zymoseptoria tritici
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Eremothecium gossypii
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Ogataea angusta
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Cyberlindnera jadinii
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Candida boidinii
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Scheffersomyces stipitis
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Candida maltosa
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Mycobacterium bovis
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Thermus aquaticus
?
-
-
-
-
Subunits
Subunits
Commentary
Organism
More
three-dimensional structure comparison, overview
Escherichia coli
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
dependent on, cofactor specificity-determining residues, overview
Acidithiobacillus ferrooxidans
NAD+
dependent on, cofactor specificity-determining residues, overview
Agrobacterium tumefaciens
NAD+
dependent on, cofactor specificity-determining residues, overview
Arthrospira platensis
NAD+
dependent on, cofactor specificity-determining residues, overview
Aspergillus niger
NAD+
dependent on, cofactor specificity-determining residues, overview
Azotobacter vinelandii
NAD+
dependent on, cofactor specificity-determining residues, overview
Bacteroides fragilis
NAD+
dependent on, cofactor specificity-determining residues, overview
Brassica napus
NAD+
dependent on, cofactor specificity-determining residues, overview
Candida boidinii
NAD+
dependent on, cofactor specificity-determining residues, overview
Candida maltosa
NAD+
dependent on, cofactor specificity-determining residues, overview
Clostridium pasteurianum
NAD+
dependent on, cofactor specificity-determining residues, overview
Cyberlindnera jadinii
NAD+
dependent on, cofactor specificity-determining residues, overview
Eremothecium gossypii
NAD+
dependent on, cofactor specificity-determining residues, overview
Escherichia coli
NAD+
dependent on, cofactor specificity-determining residues, overview
Leptospira interrogans
NAD+
dependent on, cofactor specificity-determining residues, overview
Mycobacterium bovis
NAD+
dependent on, cofactor specificity-determining residues, overview
Ogataea angusta
NAD+
dependent on, cofactor specificity-determining residues, overview
Saccharomyces cerevisiae
NAD+
dependent on, cofactor specificity-determining residues, overview
Salmonella enterica subsp. enterica serovar Typhimurium
NAD+
dependent on, cofactor specificity-determining residues, overview
Scheffersomyces stipitis
NAD+
dependent on, cofactor specificity-determining residues, overview
Thermus aquaticus
NAD+
dependent on, cofactor specificity-determining residues, overview; dependent on, cofactor specificity-determining residues, overview
Thermus thermophilus
NAD+
dependent on, cofactor specificity-determining residues, overview
Zymoseptoria tritici
Cloned(Commentary) (protein specific)
Commentary
Organism
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Acidithiobacillus ferrooxidans
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Agrobacterium tumefaciens
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Arthrospira platensis
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Aspergillus niger
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Azotobacter vinelandii
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Bacteroides fragilis
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Brassica napus
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Candida boidinii
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Candida maltosa
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Clostridium pasteurianum
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Cyberlindnera jadinii
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Eremothecium gossypii
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Escherichia coli
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Leptospira interrogans
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Mycobacterium bovis
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Ogataea angusta
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Saccharomyces cerevisiae
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Salmonella enterica subsp. enterica serovar Typhimurium
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Scheffersomyces stipitis
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Thermus aquaticus
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Thermus thermophilus
phylogenetic analysis, comparison to isocitrate dehydrogenase, EC 1.1.1.41, overview
Zymoseptoria tritici
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
dependent on, cofactor specificity-determining residues, overview
Acidithiobacillus ferrooxidans
NAD+
dependent on, cofactor specificity-determining residues, overview
Agrobacterium tumefaciens
NAD+
dependent on, cofactor specificity-determining residues, overview
Arthrospira platensis
NAD+
dependent on, cofactor specificity-determining residues, overview
Aspergillus niger
NAD+
dependent on, cofactor specificity-determining residues, overview
Azotobacter vinelandii
NAD+
dependent on, cofactor specificity-determining residues, overview
Bacteroides fragilis
NAD+
dependent on, cofactor specificity-determining residues, overview
Brassica napus
NAD+
dependent on, cofactor specificity-determining residues, overview
Candida boidinii
NAD+
dependent on, cofactor specificity-determining residues, overview
Candida maltosa
NAD+
dependent on, cofactor specificity-determining residues, overview
Clostridium pasteurianum
NAD+
dependent on, cofactor specificity-determining residues, overview
Cyberlindnera jadinii
NAD+
dependent on, cofactor specificity-determining residues, overview
Eremothecium gossypii
NAD+
dependent on, cofactor specificity-determining residues, overview
Escherichia coli
NAD+
dependent on, cofactor specificity-determining residues, overview
Leptospira interrogans
NAD+
dependent on, cofactor specificity-determining residues, overview
Mycobacterium bovis
NAD+
dependent on, cofactor specificity-determining residues, overview
Ogataea angusta
NAD+
dependent on, cofactor specificity-determining residues, overview
Saccharomyces cerevisiae
NAD+
dependent on, cofactor specificity-determining residues, overview
Salmonella enterica subsp. enterica serovar Typhimurium
NAD+
dependent on, cofactor specificity-determining residues, overview
Scheffersomyces stipitis
NAD+
dependent on, cofactor specificity-determining residues, overview
Thermus aquaticus
NAD+
dependent on, cofactor specificity-determining residues, overview
Thermus thermophilus
NAD+
dependent on, cofactor specificity-determining residues, overview
Zymoseptoria tritici
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
substrate specificity-determining residues, e.g. L103, T105, A337, and T341, overview
670847
Escherichia coli
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Thermus thermophilus
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Leptospira interrogans
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Salmonella enterica subsp. enterica serovar Typhimurium
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Clostridium pasteurianum
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Bacteroides fragilis
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Brassica napus
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Arthrospira platensis
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Acidithiobacillus ferrooxidans
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Azotobacter vinelandii
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Agrobacterium tumefaciens
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Saccharomyces cerevisiae
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Aspergillus niger
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Zymoseptoria tritici
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Eremothecium gossypii
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Ogataea angusta
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Cyberlindnera jadinii
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Candida boidinii
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Scheffersomyces stipitis
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Candida maltosa
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Mycobacterium bovis
?
-
-
-
-
additional information
substrate specificity-determining residues, overview
670847
Thermus aquaticus
?
-
-
-
-
Subunits (protein specific)
Subunits
Commentary
Organism
More
three-dimensional structure comparison, overview
Escherichia coli
Other publictions for EC 1.1.1.85
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
737729
Graczer
Dual role of the active site r ...
Thermus thermophilus
Biochemistry
55
560-574
2016
-
-
-
-
7
-
-
16
-
1
-
1
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
7
-
-
-
1
-
-
-
-
-
-
1
-
7
-
-
-
-
16
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
7
-
-
-
-
-
-
-
-
-
-
738191
Hamajima
Pressure adaptation of 3-isopr ...
Shewanella benthica, Shewanella benthica DB21MT-2, Shewanella oneidensis
Extremophiles
20
177-186
2016
-
-
2
-
6
-
-
16
-
-
-
3
-
5
-
-
2
-
-
-
-
-
3
-
-
-
-
16
-
-
-
2
-
-
-
-
-
2
2
-
6
-
-
-
-
16
-
-
-
3
-
-
-
2
-
-
-
-
3
-
-
-
-
16
-
-
-
-
-
-
-
-
8
8
738195
Takahashi
Characterization of two ?-deca ...
Sulfolobus acidocaldarius, Sulfolobus acidocaldarius MW001
Extremophiles
20
843-853
2016
-
-
1
1
-
-
-
3
-
1
1
2
-
5
-
-
1
-
-
-
-
-
6
1
-
-
-
2
-
-
-
1
-
-
-
-
-
1
1
1
-
-
-
-
-
3
-
1
1
2
-
-
-
1
-
-
-
-
6
1
-
-
-
2
-
-
-
-
-
-
-
-
2
2
738685
Lee
Structure and mechanism of iso ...
Arabidopsis thaliana
J. Biol. Chem.
291
13421-13430
2016
-
-
1
1
18
-
-
12
-
-
-
1
-
2
-
-
1
-
-
-
-
-
1
-
-
-
-
12
-
-
-
1
-
-
-
-
-
1
1
1
18
-
-
-
-
12
-
-
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
12
-
-
-
-
-
-
-
-
12
12
738239
Graczer
Glutamate 270 plays an essenti ...
Thermus thermophilus
FEBS Lett.
589
240-245
2015
-
-
-
1
1
-
-
4
-
3
-
1
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
1
-
-
-
-
-
-
1
1
1
-
-
-
-
4
-
3
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
739436
Sharma
Deciphering the dynamics of no ...
Thermus thermophilus
PLoS ONE
10
e0144294
2015
-
-
-
-
1
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
737867
Hamajima
Pressure effects on the chimer ...
Shewanella benthica, Shewanella oneidensis
Biosci. Biotechnol. Biochem.
78
469-471
2014
-
-
-
-
-
-
-
-
-
-
-
2
-
4
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
738212
Pallo
Structural and energetic basis ...
Thermus thermophilus
FEBS J.
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670847
Kalinina
Amino acid residues that deter ...
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Cloning of cDNAs encoding isop ...
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Lunzer
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Ohkuri
Increased thermal stability ag ...
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Suzuki
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Suzuki
Adaptation of a thermophilic e ...
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Imada
Structure of 3-isopropylmalate ...
Acidithiobacillus ferrooxidans
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1998
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Suzuki
Crystallization and preliminar ...
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1998
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Crystal structures of Escheric ...
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Akanuma
Effect of polar side chains at ...
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Purification, catalytic proper ...
Escherichia coli, Thermus thermophilus
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1997
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Crystal structure of 3-isoprop ...
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Purification and characterizat ...
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Hurley
Structure of 3-isopropylmalate ...
Thermus thermophilus
Structure
2
1007-1016
1994
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3-Isopropylmalate dehydrogenas ...
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Crystallization and preliminar ...
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Yamada
Purification, catalytic proper ...
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Inagaki
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Cloning and expression of the ...
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Kakinuma
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Stereochemistry of the decarbo ...
Thermus thermophilus, Thermus thermophilus HB-8
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1989
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Kohlhaw
beta-Isopropylmalate dehydroge ...
Saccharomyces cerevisiae
Methods Enzymol.
166
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1988
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Okumura
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Cloning of the beta-isopropylm ...
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52
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Katsube
Crystallization and preliminar ...
Thermus thermophilus
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1988
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Jenkinson
-
Cloning and expression of the ...
Candida albicans
FEMS Microbiol. Lett.
49
285-288
1988
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Searles
Permeabilized cell and radioch ...
Escherichia coli, Salmonella enterica subsp. enterica serovar Typhimurium
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1988
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Hamasawa
Molecular cloning and nucleoti ...
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Croft
Expression of leucine genes fr ...
Escherichia coli, Salmonella enterica subsp. enterica serovar Typhimurium, Thermus thermophilus, Thermus thermophilus HB-8
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1987
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Sekiguchi
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Cloning and DNA homology of 3- ...
Bacillus caldolyticus, Bacillus caldotenax, Bacillus subtilis, Escherichia coli, Saccharomyces cerevisiae, Thermus thermophilus
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Sekiguchi
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DNA and amino-acid sequences o ...
Bacillus coagulans, Bacillus subtilis, Saccharomyces cerevisiae, Thermus thermophilus
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36-44
1986
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4
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4
1
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639141
Urano
-
Restriction mapping and partia ...
Citrobacter freundii, Citrobacter freundii TIT 01010
J. Biotechnol.
2
39-45
1985
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1
1
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3
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2
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639142
Karube
-
Cloning and expression of Citr ...
Citrobacter freundii, Citrobacter freundii TIT 01010
Appl. Microbiol. Biotechnol.
20
340-343
1984
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1
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1
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2
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639143
Sekiguchi
Cloning of beta-isopropylmalat ...
Bacillus coagulans
Biochim. Biophys. Acta
788
267-273
1984
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1
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6
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4
3
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4
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1
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1
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1
1
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2
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1
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1
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1
1
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6
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4
3
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1
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1
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1
1
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2
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1
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639144
Kato
-
Molecular cloning and Expressi ...
Bacillus sp., Bacillus sp. no 38-2
J. Ferment. Technol.
62
77-80
1984
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1
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2
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1
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2
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639145
Ishi
-
Molecular cloning of beta-isop ...
Clostridium butyricum, Clostridium butyricum M588
Agric. Biol. Chem.
47
2313-2317
1983
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1
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2
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639146
Tanaka
Cloning of 3-isopropylmalate d ...
Thermus thermophilus, Thermus thermophilus HB-8
Biochemistry
89
677-682
1981
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1
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2
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14
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1
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4
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1
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1
1
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1
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1
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4
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2
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639147
Hsu
Leucine biosynthesis in Saccha ...
Saccharomyces cerevisiae, Saccharomyces cerevisiae SK103
J. Biol. Chem.
255
7255-7260
1980
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-
-
-
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2
1
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7
1
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3
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1
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1
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4
2
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2
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2
1
1
1
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1
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2
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1
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7
1
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1
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1
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4
2
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2
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2
1
1
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639148
Parsons
-
beta-Isopropylmalate dehydroge ...
Salmonella enterica subsp. enterica serovar Typhimurium
Methods Enzymol.
17A
793-799
1970
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-
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2
12
2
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5
2
1
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1
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1
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1
1
3
1
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1
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1
1
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2
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12
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2
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5
2
1
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1
1
3
1
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1
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1
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639149
Rabin
Isoenzymes of beta-isopropylma ...
Pseudomonas aeruginosa
Arch. Biochem. Biophys.
134
259-261
1969
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4
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1
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4
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639150
Parsons
Purification and properties of ...
Salmonella enterica subsp. enterica serovar Typhimurium
J. Biol. Chem.
244
996-1003
1969
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7
2
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2
1
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1
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1
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3
1
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1
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1
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1
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7
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2
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2
1
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1
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3
1
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1
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639151
Burns
The biosythesis of leucine. II ...
Salmonella enterica subsp. enterica serovar Typhimurium
Biochemistry
2
1053-1058
1963
-
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3
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1
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1
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1
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