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Literature summary for 1.1.1.81 extracted from

  • Coderch, R.; Lluis, C.; Bozal, J.
    Effect of salts on D-glycerate dehydrogenase kinetic behavior (1979), Biochim. Biophys. Acta, 566, 21-31.
    View publication on PubMed
Search for more literature for 1.1.1.81

Activating Compound

Activating Compound Comment Organism Structure
CsCl 80 mM, 3fold increase in hydroxypyruvate reductase activity Bos taurus
KCl 80 mM, 9fold increase in hydroxypyruvate reductase activity Bos taurus
NaCl 80 mM, 8fold increase in hydroxypyruvate reductase activity, reaction rate increases with an increase in NaCl concentration up to 200 mM, but diminishes if the salt concentration is greater Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
NaNO3 80 mM, 50% inhibition Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0038
-
 Hydroxypyruvate value increases with NaCl concentrations higher than 10 mM Bos taurus
0.0061
-
 NADH
-
 Bos taurus
0.22
-
 NAD+ D-glycerate oxidation, 50 mM, NaCl, pH 9 Bos taurus
0.522
-
 D-glycerate D-glycerate oxidation, 50 mM, NaCl, pH 9 Bos taurus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
hydroxypyruvate + NAD(P)H Bos taurus
-
 D-glycerate + NAD(P)+ + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxypyruvate + NADH + H+
-
 Bos taurus D-glycerate + NAD+
-
 r
D-glycerate + NAD+
-
 Bos taurus 3-hydroxypyruvate + NADH + H+
-
 r
hydroxypyruvate + NAD(P)H
-
 Bos taurus D-glycerate + NAD(P)+ + H+
-
 ?