BRENDA - Enzyme Database show
show all sequences of 1.1.1.80

Gas chromatographic study of the histochemical reaction for isopropanol dehydrogenase

Ploc, I.; Starka, L.; J. Chromatogr. 172, 374-378 (1979)

Data extracted from this reference:

Application
Application
Commentary
Organism
diagnostics
characterization of adrenal and gonadal tissue
Rattus norvegicus
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.00024
-
ethanol
-
Rattus norvegicus
0.00071
-
4-Methyl-1-pentanol
-
Rattus norvegicus
0.00178
-
propan-2-ol
-
Rattus norvegicus
0.00259
-
6-methyl-2-heptanol
-
Rattus norvegicus
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoplasm
activity detected in mitochondria and cytoplasm
Rattus norvegicus
5737
-
mitochondrion
-
Rattus norvegicus
5739
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
additional information
Rattus norvegicus
possibly takes part in the further metabolic reactions of the fragments formed from the side-chain of the steroid hormone precursor in the adrenals or gonads
?
-
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Rattus norvegicus
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
adrenal gland
-
Rattus norvegicus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4-methyl-1-pentanol + NAD+
-
287362
Rattus norvegicus
4-methyl-1-pentanal + NADH
-
-
-
?
4-methyl-1-pentanol + NADP+
-
287362
Rattus norvegicus
4-methyl-1-pentanal + NADPH
-
-
-
?
6-methyl-2-heptanol + NAD+
-
287362
Rattus norvegicus
6-methyl-2-heptanone + NADH + H+
-
-
-
?
6-methyl-2-heptanol + NADP+
-
287362
Rattus norvegicus
6-methyl-2-heptanone + NADPH
-
-
-
?
ethanol + NAD+
-
287362
Rattus norvegicus
ethanal + NADH
-
-
-
?
ethanol + NADP+
-
287362
Rattus norvegicus
ethanal + NADPH + H+
-
-
-
?
additional information
also acts on short-chain secondary alcohols and, slowly, on primary alcohols
287362
Rattus norvegicus
?
-
-
-
-
additional information
possibly takes part in the further metabolic reactions of the fragments formed from the side-chain of the steroid hormone precursor in the adrenals or gonads
287362
Rattus norvegicus
?
-
-
-
-
propan-2-ol + NAD+
NAD+ effectively substitutes for NADP+
287362
Rattus norvegicus
acetone + NADH
-
287362
Rattus norvegicus
?
propan-2-ol + NADP+
-
287362
Rattus norvegicus
acetone + NADPH
-
287362
Rattus norvegicus
?
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.4
7
in mitochondria
Rattus norvegicus
8.2
-
in cytoplasma
Rattus norvegicus
pH Range
pH Minimum
pH Maximum
Commentary
Organism
6
8.6
-
Rattus norvegicus
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
effectively substitutes for NADP+
Rattus norvegicus
NADP+
-
Rattus norvegicus
Application (protein specific)
Application
Commentary
Organism
diagnostics
characterization of adrenal and gonadal tissue
Rattus norvegicus
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
effectively substitutes for NADP+
Rattus norvegicus
NADP+
-
Rattus norvegicus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.00024
-
ethanol
-
Rattus norvegicus
0.00071
-
4-Methyl-1-pentanol
-
Rattus norvegicus
0.00178
-
propan-2-ol
-
Rattus norvegicus
0.00259
-
6-methyl-2-heptanol
-
Rattus norvegicus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoplasm
activity detected in mitochondria and cytoplasm
Rattus norvegicus
5737
-
mitochondrion
-
Rattus norvegicus
5739
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
additional information
Rattus norvegicus
possibly takes part in the further metabolic reactions of the fragments formed from the side-chain of the steroid hormone precursor in the adrenals or gonads
?
-
-
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
adrenal gland
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4-methyl-1-pentanol + NAD+
-
287362
Rattus norvegicus
4-methyl-1-pentanal + NADH
-
-
-
?
4-methyl-1-pentanol + NADP+
-
287362
Rattus norvegicus
4-methyl-1-pentanal + NADPH
-
-
-
?
6-methyl-2-heptanol + NAD+
-
287362
Rattus norvegicus
6-methyl-2-heptanone + NADH + H+
-
-
-
?
6-methyl-2-heptanol + NADP+
-
287362
Rattus norvegicus
6-methyl-2-heptanone + NADPH
-
-
-
?
ethanol + NAD+
-
287362
Rattus norvegicus
ethanal + NADH
-
-
-
?
ethanol + NADP+
-
287362
Rattus norvegicus
ethanal + NADPH + H+
-
-
-
?
additional information
also acts on short-chain secondary alcohols and, slowly, on primary alcohols
287362
Rattus norvegicus
?
-
-
-
-
additional information
possibly takes part in the further metabolic reactions of the fragments formed from the side-chain of the steroid hormone precursor in the adrenals or gonads
287362
Rattus norvegicus
?
-
-
-
-
propan-2-ol + NAD+
NAD+ effectively substitutes for NADP+
287362
Rattus norvegicus
acetone + NADH
-
287362
Rattus norvegicus
?
propan-2-ol + NADP+
-
287362
Rattus norvegicus
acetone + NADPH
-
287362
Rattus norvegicus
?
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.4
7
in mitochondria
Rattus norvegicus
8.2
-
in cytoplasma
Rattus norvegicus
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
6
8.6
-
Rattus norvegicus
Other publictions for EC 1.1.1.80
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
724969
Sutak
Secondary alcohol dehydrogenas ...
Trichomonas vaginalis
FEBS J.
279
2768-2780
2012
-
-
-
-
-
-
6
12
1
-
3
2
-
4
-
-
1
-
-
-
-
-
10
1
-
-
-
-
4
-
-
1
-
-
-
-
-
-
1
-
-
-
-
6
-
12
1
-
3
2
-
-
-
1
-
-
-
-
10
1
-
-
-
-
4
-
-
-
1
-
-
1
-
-
736276
Peretz
Stereospecificity of hydrogen ...
Thermoanaerobacter brockii
Int. J. Pept. Protein Res.
42
490-495
1993
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
287362
Ploc
Gas chromatographic study of t ...
Rattus norvegicus
J. Chromatogr.
172
374-378
1979
-
1
-
-
-
-
-
4
2
-
-
1
-
1
-
-
-
-
-
1
-
-
10
-
-
-
-
-
2
1
-
2
-
-
-
-
1
-
2
-
-
-
-
-
-
4
2
-
-
1
-
-
-
-
-
1
-
-
10
-
-
-
-
-
2
1
-
-
-
-
-
-
-
-