BRENDA - Enzyme Database show
show all sequences of 1.1.1.72

Glycerol dehydrogenase from rabbit muscle

Flynn, T.G.; Cromlish, J.A.; Methods Enzymol. 89, 237-242 (1982)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
2-mercaptoethanol
-
Oryctolagus cuniculus
Diphenylhydantoin
-
Oryctolagus cuniculus
formononetin 7-O-glucoside
-
Oryctolagus cuniculus
Phenobarbitol
-
Oryctolagus cuniculus
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
186
-
D-glucuronate
-
Oryctolagus cuniculus
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
34000
-
gel filtration
Oryctolagus cuniculus
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-glyceraldehyde + NADPH + H+
Oryctolagus cuniculus
-
glycerol + NADP+
-
-
r
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Oryctolagus cuniculus
-
-
-
Purification (Commentary)
Commentary
Organism
-
Oryctolagus cuniculus
Source Tissue
Source Tissue
Commentary
Organism
Textmining
skeletal muscle
-
Oryctolagus cuniculus
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
5.75
-
-
Oryctolagus cuniculus
Storage Stability
Storage Stability
Organism
-20░C, dialyzed against distilled H2O with 30 mg/ml polyethyleneglycol, or lyophilized, stable
Oryctolagus cuniculus
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4-nitrobenzaldehyde + NADPH
-
287283
Oryctolagus cuniculus
4-nitrobenzylalcohol + NADP+
-
-
-
?
D-erythrose + NADPH
-
287283
Oryctolagus cuniculus
erythritol + NADP+
-
-
-
?
D-glucose + NADPH
-
287283
Oryctolagus cuniculus
sorbitol + NADP+
-
-
-
?
D-glucuronate + NADP+
-
287283
Oryctolagus cuniculus
?
-
-
-
?
D-glyceraldehyde + NADPH + H+
-
287283
Oryctolagus cuniculus
glycerol + NADP+
-
-
-
r
D-xylose + NADPH
-
287283
Oryctolagus cuniculus
xylitol + NADP+
-
-
-
?
formaldehyde + NADPH
-
287283
Oryctolagus cuniculus
methanol + NADP+
-
-
-
?
glycolaldehyde + NADPH
-
287283
Oryctolagus cuniculus
ethyleneglycol + NADP+
-
-
-
?
L-glyceraldehyde + NADPH
-
287283
Oryctolagus cuniculus
glycerol + NADP+
-
-
-
?
methylglyoxal + NADPH
-
287283
Oryctolagus cuniculus
1-hydroxyacetone + NADP+
-
-
-
?
n-butyraldehyde + NADPH
-
287283
Oryctolagus cuniculus
n-butanol + NADP+
-
-
-
?
n-pentanal + NADPH + H+
-
287283
Oryctolagus cuniculus
n-pentanol + NADP+
-
-
-
?
propionaldehyde + NADPH
-
287283
Oryctolagus cuniculus
propanol + NADP+
-
-
-
?
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7
-
DL-glyceraldehyde reduction
Oryctolagus cuniculus
Cofactor
Cofactor
Commentary
Organism
Structure
NADH
10% of NADPH-activity
Oryctolagus cuniculus
NADP+
-
Oryctolagus cuniculus
NADPH
-
Oryctolagus cuniculus
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADH
10% of NADPH-activity
Oryctolagus cuniculus
NADP+
-
Oryctolagus cuniculus
NADPH
-
Oryctolagus cuniculus
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
2-mercaptoethanol
-
Oryctolagus cuniculus
Diphenylhydantoin
-
Oryctolagus cuniculus
formononetin 7-O-glucoside
-
Oryctolagus cuniculus
Phenobarbitol
-
Oryctolagus cuniculus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
186
-
D-glucuronate
-
Oryctolagus cuniculus
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
34000
-
gel filtration
Oryctolagus cuniculus
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-glyceraldehyde + NADPH + H+
Oryctolagus cuniculus
-
glycerol + NADP+
-
-
r
Purification (Commentary) (protein specific)
Commentary
Organism
-
Oryctolagus cuniculus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
skeletal muscle
-
Oryctolagus cuniculus
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [Ámol/min/mg]
Specific Activity Maximum [Ámol/min/mg]
Commentary
Organism
5.75
-
-
Oryctolagus cuniculus
Storage Stability (protein specific)
Storage Stability
Organism
-20░C, dialyzed against distilled H2O with 30 mg/ml polyethyleneglycol, or lyophilized, stable
Oryctolagus cuniculus
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4-nitrobenzaldehyde + NADPH
-
287283
Oryctolagus cuniculus
4-nitrobenzylalcohol + NADP+
-
-
-
?
D-erythrose + NADPH
-
287283
Oryctolagus cuniculus
erythritol + NADP+
-
-
-
?
D-glucose + NADPH
-
287283
Oryctolagus cuniculus
sorbitol + NADP+
-
-
-
?
D-glucuronate + NADP+
-
287283
Oryctolagus cuniculus
?
-
-
-
?
D-glyceraldehyde + NADPH + H+
-
287283
Oryctolagus cuniculus
glycerol + NADP+
-
-
-
r
D-xylose + NADPH
-
287283
Oryctolagus cuniculus
xylitol + NADP+
-
-
-
?
formaldehyde + NADPH
-
287283
Oryctolagus cuniculus
methanol + NADP+
-
-
-
?
glycolaldehyde + NADPH
-
287283
Oryctolagus cuniculus
ethyleneglycol + NADP+
-
-
-
?
L-glyceraldehyde + NADPH
-
287283
Oryctolagus cuniculus
glycerol + NADP+
-
-
-
?
methylglyoxal + NADPH
-
287283
Oryctolagus cuniculus
1-hydroxyacetone + NADP+
-
-
-
?
n-butyraldehyde + NADPH
-
287283
Oryctolagus cuniculus
n-butanol + NADP+
-
-
-
?
n-pentanal + NADPH + H+
-
287283
Oryctolagus cuniculus
n-pentanol + NADP+
-
-
-
?
propionaldehyde + NADPH
-
287283
Oryctolagus cuniculus
propanol + NADP+
-
-
-
?
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7
-
DL-glyceraldehyde reduction
Oryctolagus cuniculus
Other publictions for EC 1.1.1.72
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [░C]
Temperature Range [░C]
Temperature Stability [░C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [░C] (protein specific)
Temperature Range [░C] (protein specific)
Temperature Stability [░C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
711534
Richter
Characterization of a whole-ce ...
Gluconobacter oxydans
Biotechnol. Bioeng.
106
541-552
2010
-
-
1
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
1
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
712771
Richter
The Three-Dimensional Structur ...
Gluconobacter oxydans
J. Mol. Biol.
404
353-362
2010
-
-
1
1
2
-
-
3
-
-
1
-
-
2
-
-
1
-
-
-
6
-
2
1
-
-
-
4
-
-
-
-
-
-
-
-
-
1
-
1
2
-
-
-
-
3
-
-
1
-
-
-
-
1
-
-
6
-
2
1
-
-
-
4
-
-
-
-
-
-
-
-
-
-
711743
Richter
Characterisation of a recombin ...
Gluconobacter oxydans
ChemBioChem
10
1888-1896
2009
-
-
1
-
-
-
1
4
-
-
2
-
-
4
-
-
1
-
-
-
-
-
45
1
3
-
2
-
4
-
1
2
1
-
-
-
-
1
2
-
-
-
-
1
1
4
-
-
2
-
-
-
-
1
-
-
-
-
45
1
3
-
2
-
4
-
1
-
-
-
-
-
-
-
656732
Ruijter
Polyol accumulation by Aspergi ...
Aspergillus oryzae
Microbiology
150
1095-1101
2004
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
1
-
-
1
4
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
1
4
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
656831
de Vries
Glycerol dehydrogenase, encode ...
Aspergillus nidulans
Mol. Microbiol.
49
131-141
2003
1
-
1
-
-
-
-
-
-
-
1
1
-
1
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
2
-
1
-
1
-
1
2
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
287291
Sealy-Lewis H.M.; Fairhurst V.
An NADP+-dependent glycerol de ...
Aspergillus nidulans
Curr. Genet.
22
293-296
1992
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
287284
Castro
Glycerol utilization in Fusari ...
Fusarium oxysporum
J. Gen. Microbiol.
137
1497-1502
1991
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
287289
Schuurink
Purification and properties of ...
Aspergillus nidulans, Aspergillus niger
J. Gen. Microbiol.
136
1043-1050
1990
-
-
-
-
-
1
-
-
-
-
2
-
-
4
-
-
2
-
-
2
2
-
10
2
-
-
-
-
4
-
-
4
-
-
-
-
-
-
4
-
-
1
-
-
-
-
-
-
2
-
-
-
-
2
-
2
2
-
10
2
-
-
-
-
4
-
-
-
-
-
-
-
-
-
287290
Inayat
-
Regulation of NADP+-specific g ...
Aspergillus niger
Biochem. Soc. Trans.
16
976-977
1988
-
-
-
-
-
-
2
-
-
1
-
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
2
-
-
-
1
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
287283
Flynn
Glycerol dehydrogenase from ra ...
Oryctolagus cuniculus
Methods Enzymol.
89
237-242
1982
-
-
-
-
-
-
4
1
-
-
1
1
-
1
-
-
1
-
-
1
1
1
13
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
3
-
-
-
-
4
-
1
-
-
1
1
-
-
-
1
-
1
1
1
13
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
287285
Viswanath-Reddy
-
Purification and properties of ...
Neurospora crassa
J. Gen. Microbiol.
107
289-296
1978
-
-
-
-
-
-
1
4
-
-
2
1
-
1
-
-
1
-
-
-
1
1
5
1
-
-
2
-
2
-
-
2
-
-
-
-
-
-
2
-
-
-
-
1
-
4
-
-
2
1
-
-
-
1
-
-
1
1
5
1
-
-
2
-
2
-
-
-
-
-
-
-
-
-
287288
Walton
Stereochemistry of reduction o ...
Oryctolagus cuniculus
Biochemistry
12
3472-3478
1973
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
287286
Kormann
Purification and properties of ...
Oryctolagus cuniculus
Biochim. Biophys. Acta
258
40-55
1972
-
-
-
-
-
-
2
2
-
-
1
1
-
1
-
-
1
-
-
1
-
1
9
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
3
-
-
-
-
2
-
2
-
-
1
1
-
-
-
1
-
1
-
1
9
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
287287
Toews
The kinetics and reaction mech ...
Rattus norvegicus
Biochem. J.
105
1067-1073
1967
-
-
-
-
-
-
1
4
-
-
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1
-
1
-
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1
-
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1
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6
-
-
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-
-
-
-
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2
-
-
-
-
-
-
2
-
-
-
-
1
-
4
-
-
-
1
-
-
-
1
-
1
-
-
6
-
-
-
-
-
-
-
-
-
-
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-
-
-