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Literature summary for 1.1.1.71 extracted from

  • Fidge, N.H.; Goodman, D.S.
    The enzymatic reduction of retinal to retinol in rat intestine (1968), J. Biol. Chem., 243, 4372-4379.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
cysteine
-
Rattus norvegicus
GSH
-
Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
2-mercaptoethanol slight inhibition Rattus norvegicus
N-ethylmaleimide strong inhibition Rattus norvegicus
p-hydroxymercuribenzoate strong inhibition Rattus norvegicus
Sodium glycocholate
-
Rattus norvegicus
Tween 80
-
Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
ammonium sulfate, DEAE-Sephadex, Sephadex G-200, 55°C for 6 min Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzaldehyde + NAD(P)H
-
Rattus norvegicus benzyl alcohol + NAD(P)+
-
?
butanal + NAD(P)H + H+
-
Rattus norvegicus butan-1-ol + NAD(P)+
-
?
citral + NAD(P)H
-
Rattus norvegicus citrol + NAD(P)+
-
?
decanal + NAD(P)H
-
Rattus norvegicus decan-1-ol + NAD(P)+
-
?
dodecanal + NAD(P)H
-
Rattus norvegicus dodecan-1-ol + NAD(P)+
-
?
ethanal + NAD(P)H
-
Rattus norvegicus ethanol + NAD(P)+
-
?
farnesyl aldehyde + NAD(P)H
-
Rattus norvegicus farnesol + NAD(P)+
-
?
heptanal + NAD(P)H
-
Rattus norvegicus heptan-1-ol + NAD(P)+
-
?
linolenyl aldehyde + NAD(P)H
-
Rattus norvegicus linolenol + NAD(P)+
-
?
linoleyl aldehyde + NAD(P)H
-
Rattus norvegicus linoleol + NAD(P)+
-
?
octanal + NAD(P)H + H+
-
Rattus norvegicus octan-1-ol + NAD(P)+
-
?
oleyl aldehyde + NAD(P)H
-
Rattus norvegicus oleol + NAD(P)+
-
?
retinal + NAD(P)H
-
Rattus norvegicus retinol + NAD(P)+
-
?
tetradecanal + NAD(P)H
-
Rattus norvegicus tetradecan-1-ol + NAD(P)+
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.3
-
reduction of retinal, sharp decrease above pH 6.3 and below pH 6.0 Rattus norvegicus

pH Range

pH Minimum pH Maximum Comment Organism
5.5 7
-
Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NAD(P)H half maximal velocity with 0.0004 mM NADH and 0.04 mM NADPH Rattus norvegicus