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Literature summary for 1.1.1.64 extracted from

  • Baker, M.E.
    Unusual evolution of 11beta- and 17beta-hydroxysteroid dehydrogenases (1995), BioEssays, 18, 63-70.
    View publication on PubMed
Search for more literature for 1.1.1.64

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0007
-
 androstenedione
-
 Homo sapiens
0.0033
-
 estrone
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
17beta-estradiol + NADP+ Homo sapiens
-
 estrone + NADPH
-
 r
testosterone + NADP+ Homo sapiens 17beta-hydroxysterod dehydrogenase 3, reduction of androst-4-ene-3,17-dione is preferred androst-4-ene-3,17-dione + NADPH + H+
-
 r

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
17beta-estradiol + NADP+
-
 Homo sapiens estrone + NADPH
-
 r
testosterone + NADP+ 17beta-hydroxysteroid dehydrogenase 3, reduction of androst-4-ene-3,17-dione is preferred Homo sapiens androst-4-ene-3,17-dione + NADPH + H+
-
 r
testosterone + NADP+ 17beta-hydroxysterod dehydrogenase 3, reduction of androst-4-ene-3,17-dione is preferred Homo sapiens androst-4-ene-3,17-dione + NADPH + H+
-
 r

Cofactor

Cofactor Comment Organism Structure
NADP+
-
 Homo sapiens