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Literature summary for 1.1.1.62 extracted from

  • Karkola, S.; Alho-Richmond, S.; Wahala, K.
    Pharmacophore modelling of 17beta-HSD1 enzyme based on active inhibitors and enzyme structure (2009), Mol. Cell. Endocrinol., 301, 225-228.
    View publication on PubMed
Search for more literature for 1.1.1.62

Inhibitors

Inhibitors Comment Organism Structure
(1Z)-N'-[[(3,5-dimethylisoxazol-4-yl)carbonyl]oxy]-2-[4-(1,2,3-thiadiazol-4-yl)phenyl]ethanimidamide
-
 Homo sapiens
1-(4-fluorophenyl)-3-[4-(1,2,3-thiadiazol-4-yl)benzyl]urea
-
 Homo sapiens
1-[(3-hydroxyphenyl)sulfanyl]-5-oxo-4,5,7,8,9,10,11,13-octahydro-3H-indeno[2',1':4,5]pyrimido[1,2-a]azepine-2-carbaldehyde
-
 Homo sapiens
3-[(4-chlorophenyl)sulfanyl]-6-(2,4-dimethyl-1H-pyrrol-1-yl)pyridazine
-
 Homo sapiens
4-methyl-3-(trifluoromethyl)-5-[[4-(trifluoromethyl)benzyl]sulfanyl]-4H-1,2,4-triazole
-
 Homo sapiens
4-methyl-5-[6-(2,2,2-trifluoroethoxy)pyridin-3-yl]-4H-1,2,4-triazole-3-thiol
-
 Homo sapiens
4-methyl-N-[4-[4-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]benzenesulfonamide
-
 Homo sapiens
6-[(1,3-benzothiazol-2-ylsulfanyl)methyl]-4-butoxy-2-(trifluoromethyl)quinoline
-
 Homo sapiens
6-[4-(trifluoromethyl)phenoxy]pyridin-3-amine
-
 Homo sapiens
N'-[(2,4-difluorophenyl)sulfonyl]-2-pyridin-3-yl-4,5-dihydro-1,3-thiazole-4-carbohydrazide
-
 Homo sapiens
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-methyl-1,2,3-thiadiazole-5-carboxamide
-
 Homo sapiens
S-(4-fluorophenyl) 2-methyl-4-(trifluoromethyl)benzenecarbothioate
-
 Homo sapiens
[4-[4-(2-methoxyphenyl)piperidin-1-yl]-3-nitrophenyl]methanol
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P14061
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
estradiol-17beta + NADP+
-
 Homo sapiens estrone + NADPH + H+
-
 ?

Synonyms

Synonyms Comment Organism
17beta-HSD1
-
 Homo sapiens
17beta-hydroxysteroid dehydrogenase type 1
-
 Homo sapiens