Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Mus musculus | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
estrone + NADPH + H+ | Mus musculus | final step in the synthesis of active estrogens | estradiol-17beta + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
isoform 1, 17beta-HSD1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intermediate lobe | - |
Mus musculus | - |
melanotroph | - |
Mus musculus | - |
additional information | not detectable in corpora lutea, interstitial cells, anterior and posterior lobes, mammary gland, uterus, vagina, adrenal gland, kidney, liver, brain, and lung | Mus musculus | - |
ovarian follicle | high expression in granulosa cells of growing follicles | Mus musculus | - |
ovary | - |
Mus musculus | - |
prostate | only in epithelial cells | Mus musculus | - |
skin | detectable in sebaceous glands, absent in epidermis, stroma, hair follicles and sweat glands | Mus musculus | - |
testis | only in germ cells, absent in seminiferous tubules and Leydig cells | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
estrone + NADPH + H+ | - |
Mus musculus | estradiol-17beta + NADP+ | - |
? | |
estrone + NADPH + H+ | final step in the synthesis of active estrogens | Mus musculus | estradiol-17beta + NADP+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Mus musculus |