Cloned (Comment) | Organism |
---|---|
- |
Callithrix jacchus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
estrone + NADPH + H+ | Callithrix jacchus | final step in the synthesis of active estrogens, important in the maintenance of pregnancy | estradiol-17beta + NADP+ | - |
? | |
estrone + NADPH + H+ | Callithrix jacchus | final step in the synthesis of active estrogens, important in the maintenance of pregnancy | estradiol-17beta + NADP+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Callithrix jacchus | Q9GME2 | marmoset monkey, isoform 1, 17beta-HSD1 | - |
Callithrix jacchus | Q9N0M8 | marmoset monkey, isoform 7, 17beta-HSD7 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | - |
Callithrix jacchus | - |
colon | - |
Callithrix jacchus | - |
corpus luteum | detectable throughout the luteal phase of the ovarian cycle and during pregnancy | Callithrix jacchus | - |
jejunum | - |
Callithrix jacchus | - |
kidney | - |
Callithrix jacchus | - |
liver | high activity | Callithrix jacchus | - |
additional information | not detectable in brain, colon, jejunum, pancreas, kidney, liver, adrenal, prostate, testis, uterus, lung, and spleen | Callithrix jacchus | - |
additional information | not detectable in brain, lung and spleen | Callithrix jacchus | - |
pancreas | - |
Callithrix jacchus | - |
placenta | - |
Callithrix jacchus | - |
prostate gland | - |
Callithrix jacchus | - |
testis | - |
Callithrix jacchus | - |
uterus | - |
Callithrix jacchus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
estrone + NADPH + H+ | - |
Callithrix jacchus | estradiol-17beta + NADP+ | - |
? | |
estrone + NADPH + H+ | final step in the synthesis of active estrogens, important in the maintenance of pregnancy | Callithrix jacchus | estradiol-17beta + NADP+ | - |
? | |
estrone + NADPH + H+ | final step in the synthesis of active estrogens, important in the maintenance of pregnancy | Callithrix jacchus | estradiol-17beta + NADP+ | - |
r | |
estrone + NADPH + H+ | reductive activity is 1.5-3fold higher than oxidative activity | Callithrix jacchus | estradiol-17beta + NADP+ | - |
r |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Callithrix jacchus |