Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | activity with estradiol-17beta is not inhibited by high concentrations of C19-steroids or C21-steroids | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0008 | - |
estradiol-17beta | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-431 cell | - |
Homo sapiens | - |
breast cell line | - |
Homo sapiens | - |
CAOV-3 cell | - |
Homo sapiens | - |
MCF-7 cell | - |
Homo sapiens | - |
MCF-7 cell | breast cancer cell line MCF-7 | Homo sapiens | - |
MDA-MB-231 cell | - |
Homo sapiens | - |
MDA-MB-231 cell | breast cancer cell line MDA-MB-231 | Homo sapiens | - |
ovarian cancer cell | - |
Homo sapiens | - |
OVCAR-3 cell | - |
Homo sapiens | - |
placenta | - |
Homo sapiens | - |
T47D cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
estradiol-17beta + NAD+ | - |
Homo sapiens | estrone + NADH | - |
? | |
testosterone + NADP+ | - |
Homo sapiens | 4-androstene-3,17-dione + NADPH + H+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | cofactor | Homo sapiens |