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Literature summary for 1.1.1.6 extracted from

  • Nishise, H.; Maehashi, S.; Yamada, H.; Tani, Y.
    Effects of organic solvents and chemical modification on the activity of glycerol dehydrogenase (1987), Agric. Biol. Chem., 51, 3347-3353.
No PubMed abstract available
Search for more literature for 1.1.1.6

Inhibitors

Inhibitors Comment Organism Structure
1-ethyl-3(3-dimethylaminopropyl)carbodiimide
-
 Cellulomonas sp.
2,4,6-Trinitrobenzene sulfonate
-
 Cellulomonas sp.
acetone inactivation, enzyme regains activity after removal of ketone Cellulomonas sp.
Anhitol 24B
-
 Cellulomonas sp.
catechol i.e. 1,2-butanediol, inactivation, enzyme regains activity after removal of alcohol Cellulomonas sp.
Cetylpyridinium chloride strong inhibition at low concentration Cellulomonas sp.
cetyltrimethylammonium bromide strong inhibition at low concentration Cellulomonas sp.
D-xylose
-
 Cellulomonas sp.
diacetyl inactivation, enzyme regains activity after removal of ketone Cellulomonas sp.
dimethylformamide inactivation Cellulomonas sp.
Dimethylsulfoxide inactivation Cellulomonas sp.
dioxane inactivation, enzyme regains activity after removal of ketone Cellulomonas sp.
DTNB
-
 Cellulomonas sp.
ethanol 10% v/v: 25-75% loss of activity, depending on substrate, enzyme regains activity after removal of alcohol Cellulomonas sp.
iodoacetate
-
 Cellulomonas sp.
isobutanol 5% v/v: 0-50% loss of activity, depending on substrate, enzyme regains activity after removal of alcohol Cellulomonas sp.
meso-erythritol
-
 Cellulomonas sp.
methanol 10% v/v: 25-75% loss of activity, 5% v/v, 50-95% loss of activity, depending on substrate, enzyme regains activity after removal of alcohol Cellulomonas sp.
methylene blue enzyme activity is decreased by photooxidation Cellulomonas sp.
n-amyl alcohol 2% v/v: 0-50% loss of activity, depending on substrate, enzyme regains activity after removal of alcohol Cellulomonas sp.
n-butanol 5% v/v: 0-50% loss of activity, depending on substrate, enzyme regains activity after removal of alcohol Cellulomonas sp.
n-Propanol 5% v/v: 25-60% loss of activity, depending on substrate, enzyme regains activity after removal of alcohol Cellulomonas sp.
PCMB
-
 Cellulomonas sp.
Sodium dodecyl sulfate
-
 Cellulomonas sp.
sucrose
-
 Cellulomonas sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0238
-
 2,3-Butanediol
-
 Cellulomonas sp.
0.202
-
 1,2-propanediol
-
 Cellulomonas sp.
10.9
-
 glycerol
-
 Cellulomonas sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm soluble, isolation from crude cell extract Cellulomonas sp. 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glycerol + NAD+ Cellulomonas sp.
-
 dihydroxyacetone + NADH + H+
-
 ?
glycerol + NAD+ Cellulomonas sp. NT3060
-
 dihydroxyacetone + NADH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Cellulomonas sp.
-
-
-
Cellulomonas sp. NT3060
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Cellulomonas sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-propanediol + NAD+
-
 Cellulomonas sp. hydroxyacetone + NADH
-
 ?
1,2-propanediol + NAD+
-
 Cellulomonas sp. NT3060 hydroxyacetone + NADH
-
 ?
2,3-butanediol + NAD+
-
 Cellulomonas sp. 3-hydroxybutane-2-one + NADH
-
 ?
2,3-butanediol + NAD+
-
 Cellulomonas sp. NT3060 3-hydroxybutane-2-one + NADH
-
 ?
glycerol + NAD+
-
 Cellulomonas sp. dihydroxyacetone + NADH + H+
-
 ?
glycerol + NAD+
-
 Cellulomonas sp. NT3060 dihydroxyacetone + NADH + H+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Cellulomonas sp.
NADH
-
 Cellulomonas sp.