BRENDA - Enzyme Database show
show all sequences of 1.1.1.55

Enzymic conversion of lactaldehyde to propanediol

Gupta, N.K.; Robinson, W.G; J. Biol. Chem. 235, 1609-1612 (1960)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
cysteine
-
Sus scrofa
Dimercaptopropanol
-
Sus scrofa
glutathione
-
Sus scrofa
p-chloromercuribenzoate
-
Sus scrofa
thioethanol
-
Sus scrofa
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
1.9
-
L-lactaldehyde
-
Sus scrofa
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
L-lactaldehyde + NADPH + H+
Spinacia oleracea
-
propane-1,2-diol + NADP+
-
Spinacia oleracea
r
L-lactaldehyde + NADPH + H+
Pseudomonas aeruginosa
-
propane-1,2-diol + NADP+
-
Pseudomonas aeruginosa
r
L-lactaldehyde + NADPH + H+
Sus scrofa
the equilibrium greatly favors the reduction of L-lactaldehyde and can be reversed in the presence of high concentrations of propane-1,2-diol at high pH-values
propane-1,2-diol + NADP+
-
Sus scrofa
r
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Pseudomonas aeruginosa
-
-
-
Spinacia oleracea
-
-
-
Sus scrofa
-
-
-
Purification (Commentary)
Commentary
Organism
-
Sus scrofa
Source Tissue
Source Tissue
Commentary
Organism
Textmining
brain
-
Sus scrofa
-
heart
-
Sus scrofa
-
kidney
-
Sus scrofa
-
leaf
-
Spinacia oleracea
-
liver
-
Sus scrofa
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
L-lactaldehyde + NADPH + H+
-
389564
Spinacia oleracea
propane-1,2-diol + NADP+
-
389564
Spinacia oleracea
r
L-lactaldehyde + NADPH + H+
-
389564
Pseudomonas aeruginosa
propane-1,2-diol + NADP+
-
389564
Pseudomonas aeruginosa
r
L-lactaldehyde + NADPH + H+
the equilibrium greatly favors the reduction of L-lactaldehyde and can be reversed in the presence of high concentrations of propane-1,2-diol at high pH-values
389564
Sus scrofa
propane-1,2-diol + NADP+
-
389564
Sus scrofa
r
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.4
-
-
Sus scrofa
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
cysteine
-
Sus scrofa
Dimercaptopropanol
-
Sus scrofa
glutathione
-
Sus scrofa
p-chloromercuribenzoate
-
Sus scrofa
thioethanol
-
Sus scrofa
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
1.9
-
L-lactaldehyde
-
Sus scrofa
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
L-lactaldehyde + NADPH + H+
Spinacia oleracea
-
propane-1,2-diol + NADP+
-
Spinacia oleracea
r
L-lactaldehyde + NADPH + H+
Pseudomonas aeruginosa
-
propane-1,2-diol + NADP+
-
Pseudomonas aeruginosa
r
L-lactaldehyde + NADPH + H+
Sus scrofa
the equilibrium greatly favors the reduction of L-lactaldehyde and can be reversed in the presence of high concentrations of propane-1,2-diol at high pH-values
propane-1,2-diol + NADP+
-
Sus scrofa
r
Purification (Commentary) (protein specific)
Commentary
Organism
-
Sus scrofa
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
brain
-
Sus scrofa
-
heart
-
Sus scrofa
-
kidney
-
Sus scrofa
-
leaf
-
Spinacia oleracea
-
liver
-
Sus scrofa
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
L-lactaldehyde + NADPH + H+
-
389564
Spinacia oleracea
propane-1,2-diol + NADP+
-
389564
Spinacia oleracea
r
L-lactaldehyde + NADPH + H+
-
389564
Pseudomonas aeruginosa
propane-1,2-diol + NADP+
-
389564
Pseudomonas aeruginosa
r
L-lactaldehyde + NADPH + H+
the equilibrium greatly favors the reduction of L-lactaldehyde and can be reversed in the presence of high concentrations of propane-1,2-diol at high pH-values
389564
Sus scrofa
propane-1,2-diol + NADP+
-
389564
Sus scrofa
r
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.4
-
-
Sus scrofa
Other publictions for EC 1.1.1.55
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
389565
Nambiar
-
A mechanistic basis for the st ...
Sus scrofa
J. Am. Chem. Soc.
105
5886-90
1983
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
389564
Gupta
Enzymic conversion of lactalde ...
Pseudomonas aeruginosa, Spinacia oleracea, Sus scrofa
J. Biol. Chem.
235
1609-1612
1960
-
-
-
-
-
-
5
1
-
-
-
3
-
3
-
-
1
-
-
5
-
-
3
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
1
-
-
-
3
-
-
-
1
-
5
-
-
3
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-