BRENDA - Reference to 1.1.1.51; Id = 670033

DNA and amino acid sequence determination and analysis, chromosome metaphase, interphase mapping, i.e. FISH mapping, localization on chromosome 10q11.2, stable expression in HEK-293 cells

Homo sapiens

dihydrotestosterone + NADPH + H+

Homo sapiens

androsterone inactivation

5alpha-androstane-3beta,17beta-diol + NADP+

-

?

estrone + NADPH

Homo sapiens

estrogen activation

estradiol + NADP+

-

?

additional information

Homo sapiens

the isozyme might play an imporant role in modulation of active hormone levels in estrogen-sensitive cells or tissues

?

-

zymosterone + NADPH

Homo sapiens

-

zymosterol + NADP+

-

?

Homo sapiens

-

dihydrotestosterone + NADPH + H+

androsterone inactivation

670033

Homo sapiens

5alpha-androstane-3beta,17beta-diol + NADP+

-

?

estrone + NADPH

estrogen activation

670033

Homo sapiens

estradiol + NADP+

-

?

additional information

the isozyme might play an imporant role in modulation of active hormone levels in estrogen-sensitive cells or tissues

670033

Homo sapiens

?

-

zymosterone + NADPH

-

670033

Homo sapiens

zymosterol + NADP+

-

?

NADPH

-

Homo sapiens

DNA and amino acid sequence determination and analysis, chromosome metaphase, interphase mapping, i.e. FISH mapping, localization on chromosome 10q11.2, stable expression in HEK-293 cells

Homo sapiens

NADPH

-

Homo sapiens

dihydrotestosterone + NADPH + H+

Homo sapiens

androsterone inactivation

5alpha-androstane-3beta,17beta-diol + NADP+

-

?

estrone + NADPH

Homo sapiens

estrogen activation

estradiol + NADP+

-

?

additional information

Homo sapiens

the isozyme might play an imporant role in modulation of active hormone levels in estrogen-sensitive cells or tissues

?

-

zymosterone + NADPH

Homo sapiens

-

zymosterol + NADP+

-

?

dihydrotestosterone + NADPH + H+

androsterone inactivation

670033

Homo sapiens

5alpha-androstane-3beta,17beta-diol + NADP+

-

?

estrone + NADPH

estrogen activation

670033

Homo sapiens

estradiol + NADP+

-

?

additional information

the isozyme might play an imporant role in modulation of active hormone levels in estrogen-sensitive cells or tissues

670033

Homo sapiens

?

-

zymosterone + NADPH

-

670033

Homo sapiens

zymosterol + NADP+

-

?

740156

Kenmogne

Synthesis of a dansyl-labeled ...

Homo sapiens

Bioorg. Med. Chem. Lett.

26

2179-2183

2016

-

1

-

2

-

1

-

1

-

1

-

1

-

2

-

2

-

1

-

2

-

2

-

1

-

1

-

1

-

740292

Yu

Characterization of 3,17beta-h ...

Comamonas testosteroni, Comamonas testosteroni ATCC 119960

Chem. Biol. Interact.

234

221-228

2015

-

1

-

1

-

4

-

3

-

4

-

2

-

1

2

-

1

-

4

-

4

-

1

2

1

-

740637

Endo

Characterization of hamster NA ...

Mesocricetus auratus

J. Biochem.

158

425-434

2015

-

1

-

2

-

10

34

1

-

3

-

1

-

12

-

41

1

-

33

1

-

5

8

-

10

-

1

5

-

2

-

10

8

34

1

-

1

-

12

-

41

1

-

33

1

-

3

-

33

740916

Roy

Reprint of in vitro and in viv ...

Homo sapiens, Rattus norvegicus, Rattus norvegicus Sprague-Dawley

J. Steroid Biochem. Mol. Biol.

153

170-178

2015

-

1

-

3

-

1

-

3

-

3

-

1

-

3

-

1

-

1

-

4

-

1

4

-

3

-

1

-

3

-

1

-

3

-

1

-

1

-

2

-

741000

Mansour

Oxidative activity of 17beta-h ...

Homo sapiens

Mol. Cell. Endocrinol.

414

168-176

2015

-

1

-

1

-

1

-

1

-

3

-

1

-

1

-

1

-

1

-

3

-

1

-

1

-

740161

Flanagan

Morpholylureas are a new class ...

Homo sapiens

Bioorg. Med. Chem.

22

967-977

2014

-

1

-

61

-

1

-

1

-

1

-

1

-

1

-

1

-

2

-

2

1

-

61

-

1

-

1

-

1

-

1

-

1

-

740501

Aceves-Ramos

Cloning, characterization and ...

Taenia solium

Gen. Comp. Endocrinol.

203

186-192

2014

-

1

-

2

-

8

-

1

-

2

-

2

-

1

2

-

2

-

1

-

2

-

2

-

740911

Roy

In vitro and in vivo evaluatio ...

Rattus norvegicus

J. Steroid Biochem. Mol. Biol.

141

44-51

2014

-

3

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

2

-

4

-

2

-

4

3

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

740307

Li

A novel transcriptional repres ...

Comamonas testosteroni, Comamonas testosteroni ATCC 119960

Chem.-Biol. Interact.

202

116-125

2013

-

1

-

1

-

3

-

1

-

1

-

1

-

1

-

3

-

740329

Yepuru

Steroidogenic enzyme AKR1C3 is ...

Homo sapiens

Clin. Cancer Res.

19

5613-5625

2013

1

-

1

-

1

-

2

-

2

-

3

-

3

-

2

-

4

-

1

-

1

4

-

1

-

2

-

2

-

3

-

2

-

3

-

725824

Svegelj

The role of Ala231 and Trp227 ...

Curvularia lunata

J. Steroid Biochem. Mol. Biol.

129

92-98

2012

-

1

-

1

-

2

-

1

-

2

-

699146

Bruzzone

Immunohistochemical localizati ...

Pelophylax esculentus

J. Chem. Neuroanat.

39

35-50

2010

-

1

-

1

-

3

-

1

-

1

-

1

-

3

-

711161

Nashev

The UV-filter benzophenone-1 i ...

Homo sapiens, Mus musculus, Rattus norvegicus

Biochem. Pharmacol.

79

1189-1199

2010

-

3

-

16

-

6

-

2

-

1

-

3

-

3

-

14

-

3

-

14

16

-

2

-

1

-

3

-

3

-

712881

Zhao

Inhibition of 3beta- and 17bet ...

Rattus norvegicus

J. Steroid Biochem. Mol. Biol.

118

13-17

2010

-

1

-

2

-

1

-

2

-

4

-

4

-

4

1

4

1

-

1

-

2

-

713329

Ernst

Expression of 3beta-HSD and P5 ...

Digitalis lanata

Planta Med.

76

923-927

2010

-

1

-

4

-

5

-

4

-

4

-

1

-

1

-

4

-

4

-

4

-

1

-

696052

Higo

Comparison of sex-steroid synt ...

Rattus norvegicus

Biochem. Biophys. Res. Commun.

385

62-66

2009

-

1

-

1

-

4

-

1

-

1

-

1

-

4

-

700177

Senthilkumaran

Novel 3beta-hydroxysteroid deh ...

Oreochromis niloticus

Mol. Cell. Endocrinol.

299

146-152

2009

-

1

-

2

-

1

-

4

-

1

-

2

-

2

-

4

-

700188

Chura

Steroid-converting enzymes in ...

Homo sapiens

Mol. Cell. Endocrinol.

301

51-58

2009

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

712925

De Catalfo

Influence of commercial dietar ...

Rattus norvegicus

Lipids

44

345-357

2009

-

1

-

2

1

-

2

1

-

686428

Arukwe

Modulation of steroidogenesis ...

Danio rerio

Environ. Res.

107

362-370

2008

-

1

-

1

-

1

-

686929

Prisco

Immunolocalization of 3beta-HS ...

Torpedo marmorata

Gen. Comp. Endocrinol.

155

157-163

2008

-

3

-

3

-

3

-

690081

Parthasarathy

Assessment of in vitro effects ...

Rattus norvegicus

Steroids

73

328-338

2008

-

1

-

1

-

1

-

691108

Hunter

Transformation of 5-ene steroi ...

Aspergillus tamarii, Aspergillus tamarii KITA

Biochim. Biophys. Acta

1791

110-117

2008

-

5

-

6

-

1

-

1

-

6

-

684324

Aizawa

Expression of steroidogenic en ...

Rattus norvegicus

Am. J. Physiol.

292

E577-E584

2007

-

1

-

2

-

2

-

687324

Chen

Gene expression of 3beta-hydro ...

Sus scrofa

J. Anim. Sci.

85

2457-2463

2007

-

2

-

2

-

2

-

688683

Luu-The

Steroid metabolism and profile ...

Homo sapiens

J. Steroid Biochem. Mol. Biol.

107

30-36

2007

-

2

-

1

-

1

-

689697

Herl

Delta5-3beta-hydroxysteroid de ...

Digitalis lanata

Planta Med.

73

704-710

2007

-

1

-

8

-

1

-

3

-

1

-

1

-

6

1

-

1

-

1

-

1

-

8

-

1

-

1

-

1

-

6

1

-

1

-

1

-

670259

Ngatcha

3beta-Alkyl-androsterones as i ...

Homo sapiens

Mol. Cell. Endocrinol.

248

225-232

2006

-

5

-

1

-

1

-

1

-

1

-

1

-

5

-

1

-

1

-

670273

Luu-The

Characterization of type 12 17 ...

Homo sapiens

Mol. Endocrinol.

20

437-443

2006

-

1

-

1

-

1

-

2

-

2

-

1

-

1

-

1

-

1

-

2

-

672586

Fink

Identification of a novel seri ...

Homo sapiens

Bioorg. Med. Chem. Lett.

16

1532-1536

2006

-

44

-

1

-

2

-

2

-

1

-

46

-

1

-

46

44

-

2

-

2

-

673553

Ulrih

Conformational stability of 17 ...

Curvularia lunata

FEBS J.

273

3927-3937

2006

-

2

-

1

-

2

-

1

-

2

-

1

2

-

2

-

2

-

1

-

1

-

2

-

1

2

-

675983

Lukacik

Structure and function of huma ...

Homo sapiens

Mol. Cell. Endocrinol.

248

61-71

2006

-

1

-

3

-

2

-

5

-

4

-

1

-

1

-

1

-

3

-

5

-

4

-

669784

Tchedam Ngatcha

Androsterone 3alpha-ether-3bet ...

Homo sapiens

J. Med. Chem.

48

5257-5268

2005

-

1

-

8

-

1

-

1

-

1

-

1

-

1

-

6

-

1

-

6

8

-

1

-

1

-

1

-

669905

Mindnich

Androgen metabolism via 17beta ...

Danio rerio, Homo sapiens

J. Mol. Endocrinol.

35

305-316

2005

-

2

-

2

-

4

-

5

-

6

-

17

-

6

-

2

6

-

2

-

4

-

6

-

17

-

670033

Liu

Cloning and characterization o ...

Homo sapiens

J. Steroid Biochem. Mol. Biol.

94

173-179

2005

-

1

-

4

-

3

-

4

-

1

-

1

-

4

-

4

-

670037

Durocher

Characterization of the guinea ...

Cavia porcellus

J. Steroid Biochem. Mol. Biol.

97

289-298

2005

-

1

-

1

-

6

-

6

-

2

1

-

1

-

1

-

1

-

6

-

2

1

-

672862

Degtyar

Reductase activity of 17beta-h ...

Homo sapiens

Bull. Exp. Biol. Med.

139

715-717

2005

-

3

-

2

-

2

1

-

3

-

1

-

1

-

3

-

2

1

-

3

-

675476

Zhou

Cloning, expression and charac ...

Oreochromis niloticus

J. Mol. Endocrinol.

35

103-116

2005

-

1

-

1

-

5

-

10

-

2

-

1

-

1

-

2

-

1

2

-

1

-

10

-

2

-

1

-

1

-

677079

Chapman

Mitochondrial 3 beta-hydroxyst ...

Mus musculus

Reprod. Biol. Endocrinol.

3

11

2005

-

4

-

1

-

4

-

1

-

4

1

-

2

-

1

-

1

-

1

-

1

-

4

-

1

-

1

-

4

1

-

2

-

1

-

1

-

657673

Khan

Human 17beta-hydroxysteroid de ...

Homo sapiens

Arch. Biochem. Biophys.

429

50-59

2004

-

2

-

2

-

2

-

2

-

2

-

2

-

2

-

658489

Poirier

Inhibitors of 17beta-hydroxyst ...

Homo sapiens, Rattus norvegicus

Curr. Med. Chem.

10

453-477

2003

-

26

-

1

-

3

-

5

-

4

-

8

5

-

8

-

8

-

8

26

5

-

1

-

5

-

4

-

657922

Benach

Structure of bacterial 3beta/1 ...

Comamonas testosteroni

Biochemistry

41

14659-14668

2002

-

1

-

2

-

1

-

1

-

1

-

659176

Lu

Purification, reconstitution, ...

Homo sapiens

J. Biol. Chem.

277

22123-22130

2002

-

1

-

3

9

1

-

2

-

2

-

1

-

1

8

1

-

9

-

4

-

1

4

-

3

-

9

1

-

2

-

1

-

1

8

1

-

9

-

712092

Darvas

Progesterone in Periplaneta am ...

Periplaneta americana

Gen. Comp. Endocrinol.

107

450-460

1997

-

1

-

2

6

-

1

-

2

6

-

1

-

713515

Tóth

Activity and inhibition of 3-b ...

Homo sapiens

Skin Pharmacol. Physiol.

10

160-168

1997

-

3

1

-

1

-

1

3

-

1

-

3

-

3

-

1

-

1

3

-

1

-

287080

Benach

Crystallization and crystal pa ...

Comamonas testosteroni, Comamonas testosteroni ATTC 11996

Eur. J. Biochem.

236

144-148

1996

-

1

-

2

-

1

-

712201

Tóth

In vitro inhibition of testicu ...

Homo sapiens, Rattus norvegicus, Rattus norvegicus Wistar

Int. Urol. Nephrol.

28

337-348

1996

-

1

-

2

-

169

-

2

-

3

-

1

-

2

-

2

-

3

-

287078

Minard

3beta, 17beta-Hydroxysteroid d ...

Comamonas testosteroni

FEBS Lett.

188

85-90

1985

-

2

-

2

-

2

-

287079

Stokes

Characterization of DELTA4-3-k ...

Clostridium innocuum

Biochim. Biophys. Acta

836

255-261

1985

-

1

-

1

-

3

-

1

-

1

-

2

-

2

-

1

-

1

-

1

-

1

-

287077

Kwan

-

Kinetic studies of 3alpha- and ...

Sus scrofa

Biochem. Soc. Trans.

12

842-843

1984

-

3

-

1

-

1

-

2

-

2

-

2

-

3

-

1

-

2

-

287076

Shen

The induction, purification an ...

Cavia porcellus

J. Steroid Biochem.

10

187-193

1979

-

2

1

-

1

-

1

-

1

-

1

-

1

-

1

-

2

1

-

1

-

1

-

1

-

287074

Schultz

3(17)beta-Hydroxysteroid dehyd ...

Comamonas testosteroni

J. Biol. Chem.

252

3784-3790

1977

-

4

-

1

-

3

-

5

-

5

-

4

-

3

-

287075

Schultz

3(17)beta-Hydroxysteroid dehyd ...

Comamonas testosteroni

J. Biol. Chem.

252

3775-3783

1977

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

287073

Heyns

A 3(17)beta-hydroxysteroid deh ...

Rattus norvegicus, Rattus norvegicus Wistar

Biochim. Biophys. Acta

358

1-13

1974

-

7

6

-

1

-

5

168

-

1

-

1

-

13

-

2

-

1

2

-

2

-

7

-

6

-

1

-

5

-

1

-

1

-

13

-

2

-

1

-

287081

Stevenson

Purification of male guinea pi ...

Cavia porcellus

Endocrinology

95

766-770

1974

-

1

-

287072

Mulder

Isolation and characterization ...

Homo sapiens

Biochem. J.

127

649-659

1972

-

3

2

1

-

1

-

1

-

1

-

1

-

1

6

-

2

-

2

-

3

-

2

1

-

1

-

1

-

1

-

1

6

-

287071

Dahm

-

Anreicherung einer 17beta-hydr ...

Rattus norvegicus, Rattus norvegicus Wistar

Hoppe-Seyler's Z. Physiol. Chem.

336

63-68

1964

-

2

1

-

168

-

1

-

2

-

1

-

1

-

1

-

2

-

1

-

1

-

2

-

1

-

Cloning and characterization of human form 2 type 7 17beta-hydroxysteroid dehydrogenase, a primarily 3beta-keto reductase and estrogen activating and androgen inactivating enzyme

Data extracted from this reference: