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Literature summary for 1.1.1.44 extracted from

  • Al-Quadan, F.; Wender, S.H.; Smith, E.C.
    The effect of some phenolic compounds on the activity of 6-phosphogluconate dehydrogenase from tobacco tissue cultures (1981), Phytochemistry, 20, 961-964.
No PubMed abstract available

Activating Compound

Activating Compound Comment Organism Structure
2,3-diphosphoglycerate activates both isoenzymes up to 200% of their original activity Nicotiana tabacum

Inhibitors

Inhibitors Comment Organism Structure
6-methoxy-7-hydroxycoumarin scopolin Nicotiana tabacum
caffeic acid
-
Nicotiana tabacum
chlorogenic acid
-
Nicotiana tabacum
D-Glucose 1,6-bisphosphate
-
Nicotiana tabacum
esculetin
-
Nicotiana tabacum
esculin
-
Nicotiana tabacum
ferulic acid
-
Nicotiana tabacum
p-coumaric acid
-
Nicotiana tabacum
scopoletin
-
Nicotiana tabacum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
69000 72000 2 isoenzymes, gel filtration Nicotiana tabacum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6-phospho-D-gluconate + NADP+ Nicotiana tabacum enzyme specific for the oxidative pentose phosphate pathway D-ribulose 5-phosphate + CO2 + NADPH + H+
-
r
6-phospho-D-gluconate + NADP+ Nicotiana tabacum W-38 enzyme specific for the oxidative pentose phosphate pathway D-ribulose 5-phosphate + CO2 + NADPH + H+
-
r

Organism

Organism UniProt Comment Textmining
Nicotiana tabacum
-
W-38
-
Nicotiana tabacum W-38
-
W-38
-

Purification (Commentary)

Purification (Comment) Organism
-
Nicotiana tabacum

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
Nicotiana tabacum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6-phospho-D-gluconate + NADP+
-
Nicotiana tabacum D-ribulose 5-phosphate + CO2 + NADPH + H+
-
r
6-phospho-D-gluconate + NADP+ enzyme specific for the oxidative pentose phosphate pathway Nicotiana tabacum D-ribulose 5-phosphate + CO2 + NADPH + H+
-
r
6-phospho-D-gluconate + NADP+
-
Nicotiana tabacum W-38 D-ribulose 5-phosphate + CO2 + NADPH + H+
-
r
6-phospho-D-gluconate + NADP+ enzyme specific for the oxidative pentose phosphate pathway Nicotiana tabacum W-38 D-ribulose 5-phosphate + CO2 + NADPH + H+
-
r