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Literature summary for 1.1.1.363 extracted from

  • Levy, H.R.; Daouk, G.H.; Katopes, M.A.
    Regulation of coenzyme utilization by the dual nucleotide-specific glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroids (1979), Arch. Biochem. Biophys., 198, 406-413.
    View publication on PubMed
Search for more literature for 1.1.1.363

Activating Compound

Activating Compound Comment Organism Structure
NADP+ increasing NADPH/NADP+ concentration ratios inhibit the NADP-linked, but stimulate the NAD-linked reaction Leuconostoc mesenteroides
NADPH increasing NADPH/NADP+ concentration ratios inhibit the NADP-linked, but stimulate the NAD-linked reaction Leuconostoc mesenteroides

Inhibitors

Inhibitors Comment Organism Structure
acetyl-CoA inhibition is greatly diminished at high glucose 6-phosphate concentration Leuconostoc mesenteroides
ATP inhibition is greatly diminished at high glucose 6-phosphate concentration Leuconostoc mesenteroides
NADP+ increasing NADPH/NADP+ concentration ratios inhibit the NADP-linked, but stimulate the NAD-linked reaction Leuconostoc mesenteroides
NADPH increasing NADPH/NADP+ concentration ratios inhibit the NADP-linked, but stimulate the NAD-linked reaction Leuconostoc mesenteroides
palmitoyl-CoA inhibition is greatly diminished at high glucose 6-phosphate concentration Leuconostoc mesenteroides

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-glucose 6-phosphate + NAD+ Leuconostoc mesenteroides
-
 6-phospho-D-glucono-1,5-lactone + NADH + H+
-
 ?
D-glucose 6-phosphate + NADP+ Leuconostoc mesenteroides
-
 6-phospho-D-glucono-1,5-lactone + NADPH + H+
-
 ?

Organism

Organism UniProt Comment Textmining
Leuconostoc mesenteroides
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glucose 6-phosphate + NAD+
-
 Leuconostoc mesenteroides 6-phospho-D-glucono-1,5-lactone + NADH + H+
-
 ?
D-glucose 6-phosphate + NADP+
-
 Leuconostoc mesenteroides 6-phospho-D-glucono-1,5-lactone + NADPH + H+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Leuconostoc mesenteroides
NADP+
-
 Leuconostoc mesenteroides