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Literature summary for 1.1.1.35 extracted from

  • Wakil, S.J.; Green, D.E.; Mil, S.; Mahler, H.R.
    Studies on the fatty acid oxidizing system of animal tissues. IV. beta-hydroxyacyl coenzyme A dehydrogenase (1954), J. Biol. Chem., 207, 631-638.
    View publication on PubMed
Search for more literature for 1.1.1.35

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.1
-
 (S)-3-hydroxylauryl-CoA
-
 Bos taurus
0.31
-
 (S)-3-hydroxybutyryl-CoA
-
 Bos taurus
0.34
-
 (S)-3-hydroxyhexanoyl-CoA
-
 Bos taurus
0.35
-
 (S)-3-hydroxyoctanoyl-CoA
-
 Bos taurus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Bos taurus 5739
-

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
ammonium sulfate, 50°C for 20 min, Zn(OH)2-gel Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6
-
-
 Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(S)-3-hydroxybutyryl-CoA + NAD+
-
 Bos taurus acetoacetyl-CoA + NADH
-
 r
(S)-3-hydroxydecanoyl-CoA + NAD+
-
 Bos taurus 3-ketodecanoyl-CoA + NADH
-
 ?
(S)-3-hydroxyhexanoyl-CoA + NAD+
-
 Bos taurus 3-oxohexanoyl-CoA + NADH + H+
-
 ?
(S)-3-hydroxylauryl-CoA + NAD+
-
 Bos taurus 3-oxolauryl-CoA + NADH
-
 r
3-ketooctanoyl-CoA + NADH
-
 Bos taurus (S)-3-hydroxyoctanoyl-CoA + NAD+
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
10
-
-
 Bos taurus

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Bos taurus