Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.341 extracted from

  • Hone, D.M.; Harris, A.M.; Lim, V.; Levine, M.M.
    Construction and characterization of isogenic O-antigen variants of Salmonella typhi (1994), Mol. Microbiol., 13, 525-530.
    View publication on PubMed

Application

Application Comment Organism
medicine insertion of the gene rfbJ encoding abequose synthase into a suicide vector and integration into the rfb clusters of wild-type Salmonella typhi Vi-positive strain ISP 1820, Salmonella typhi Vi-negative strain H400, and a double aro mutant of Salmonella typhi ISP 1820, strain CVD 906. Strains carrying the vector express the O4 antigen in place of the O9 antigen in the lipopolysaccharide molecule. Results support the hypothesis that the chemical composition of the Salmonella 0-antigen influences the interaction of individual serotypes with complement Salmonella enterica subsp. enterica serovar Typhi

Organism

Organism UniProt Comment Textmining
Salmonella enterica subsp. enterica serovar Typhi
-
-
-
Salmonella enterica subsp. enterica serovar Typhi LT2
-
-
-

General Information

General Information Comment Organism
physiological function insertion of the gene rfbJ encoding abequose synthase into a suicide vector and integration into the rfb clusters of wild-type Salmonella typhi Vi-positive strain ISP 1820, Salmonella typhi Vi-negative strain H400, and a double aro mutant of Salmonella typhi ISP 1820, strain CVD 906. Strains carrying the vector express the O4 antigen in place of the O9 antigen in the lipopolysaccharide molecule. Results suggest that the development of the 0-antigen serotype diversity of Salmonella is probably the result of both sequence divergence and recombination between heterologous rfb sequences. In addition, the results support the hypothesis that the chemical composition of the Salmonella 0-antigen influences the interaction of individual serotypes with complement Salmonella enterica subsp. enterica serovar Typhi