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Literature summary for 1.1.1.34 extracted from

  • Lee, T.M.; Lin, M.S.; Chou, T.F.; Chang, N.C.
    Additive effects of combined blockade of AT1 receptor and HMG-CoA reductase on left ventricular remodeling in infarcted rats (2006), Am. J. Physiol. Heart Circ. Physiol., 291, H1281-H1289.
    View publication on PubMed

Application

Application Comment Organism
medicine dual therapy with the HMG-CoA reductase inhibitor pravastatin and the angiotensin receptor antagonist olmesartan, which produce an additive reduction in cardiomyocyte hypertrophy and cardiac fibrosis after myocardial infarction through different mechanisms, decreases the propensity of the heart to arrhythmogenesis Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining