Inhibitors | Comment | Organism | Structure |
---|---|---|---|
adenosine-2'-monophospho-5'-diphosphoribose | competitive inhibitor for NADPH binding site | Rattus norvegicus | |
Compactin | competitive inhibitor for HMG-CoA binding site | Rattus norvegicus | |
lovastatin | competitive inhibitor for HMG-CoA binding site | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-hydroxy-3-methylglutaryl-CoA + NADPH | Rattus norvegicus | - |
(R)-mevalonate + CoA + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | activity is regulated by phosphorylation and dephosphorylation | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-hydroxy-3-methylglutaryl-CoA + NADPH | - |
Rattus norvegicus | (R)-mevalonate + CoA + NADP+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Rattus norvegicus |