Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.330 extracted from

  • Pang, Y.; Song, W.Q.; Chen, F.Y.; Qin, Y.M.
    A new cotton SDR family gene encodes a polypeptide possessing aldehyde reductase and 3-ketoacyl-CoA reductase activities (2010), Biochemistry (Moscow), 75, 320-326.
    View publication on PubMed
Search for more literature for 1.1.1.330

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Gossypium hirsutum

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.012
-
 NADPH pH 7.5, 37°C Gossypium hirsutum
0.026
-
 Nonanal pH 7.5, 37°C Gossypium hirsutum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
34500
-
 x * 34500, calculated and SDS-PAGE Gossypium hirsutum

Organism

Organism UniProt Comment Textmining
Gossypium hirsutum Q0VH86
-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information gene KCR3 transcripts accumulate in rapidly elongating fibers, roots and stem. Expression is found in all of the cotton tissues tested, including ovules, roots, leaves, and flowers Gossypium hirsutum
-
root gene KCR3 transcripts accumulate in rapidly elongating fibers, roots and stem Gossypium hirsutum
-
stem gene KCR3 transcripts accumulate in rapidly elongating fibers, roots and stem Gossypium hirsutum
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-oxostearoyl-CoA + NADPH + H+
-
 Gossypium hirsutum 3-hydroxystearoyl-CoA + NADP+
-
 ?
nonanal + NADPH + H+
-
 Gossypium hirsutum 1-nonanol + NADP+
-
 ?

Subunits

Subunits Comment Organism
? x * 34500, calculated and SDS-PAGE Gossypium hirsutum

Synonyms

Synonyms Comment Organism
3-ketoacyl-CoA reductase
-
 Gossypium hirsutum
KCR3
-
 Gossypium hirsutum

Cofactor

Cofactor Comment Organism Structure
additional information no cofactor: NADH Gossypium hirsutum
NADPH specific for NADPH Gossypium hirsutum

General Information

General Information Comment Organism
physiological function gene is able to complement the yeast ybr159w deletion mutant. Yeast ybr159w deletion mutant cells expressing the gene produce very long-chain fatty acids, especially C26:0. Enzyme does not participate in plastid de novo fatty acid synthesis pathway but is possibly involved in a cytosolic fatty acid elongation system Gossypium hirsutum