Organism | UniProt | Comment | Textmining |
---|---|---|---|
Photorhabdus luminescens | Q7N2B2 | - |
- |
Photorhabdus luminescens DSM 15139 | Q7N2B2 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
erythronate-4-phosphate dehydrogenase | - |
Photorhabdus luminescens |
PDXB | - |
Photorhabdus luminescens |
General Information | Comment | Organism |
---|---|---|
physiological function | the pdxB gene, encoding erythronate-4-phosphate dehydrogenase, is required for de novo vitamin B6 biosynthesis. Mutation in pdxB causes growth deficiency of Photorhabdus luminescens in nutrient-poor medium, which is restored under nutrient-rich conditions or by supplementation with pyridoxal 5'-phosphate. Supplementation with pyridoxal, pyridoxine, and pyridoxamine also restores the growth of the pdxB mutant. Supplementation with pyridoxal 5'-phosphate restores the virulence-deficient phenotype against Caenorhabditis elegans | Photorhabdus luminescens |