Literature summary for 1.1.1.29 extracted from

Corpas, F.J.; Leterrier, M.; Begara-Morales, J.C.; Valderrama, R.; Chaki, M.; Lopez-Jaramillo, J.; Luque, F.; Palma, J.M.; Padilla, M.N.; Sanchez-Calvo, B.; Mata-Perez, C.; Barroso, J.B.
Inhibition of peroxisomal hydroxypyruvate reductase (HPR1) by tyrosine nitration (2013), Biochim. Biophys. Acta, 1830, 4981-4989.

Search for more literature for 1.1.1.29

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli strain BIVU0811	Arabidopsis thaliana

Inhibitors

Inhibitors	Comment	Organism	Structure
GSH	about 72% residual activity at 2 mM	Arabidopsis thaliana
additional information	not inhibited by H2O2	Arabidopsis thaliana
S-nitrosoglutathione	about 80% residual activity at 2 mM	Arabidopsis thaliana
SIN-1	about 35% residual activity at 1 mM	Arabidopsis thaliana

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
peroxisome	-	Arabidopsis thaliana	5777	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
42300	-	-	Arabidopsis thaliana
63500	-	-	Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
hydroxypyruvate + NADH + H+	Arabidopsis thaliana	-	D-glycerate + NAD+	-	?

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	Q9C9W5	-	-

Purification (Commentary)

Purification (Comment)	Organism
LYTRA column chromatography, and Superdex 200 gel filtration	Arabidopsis thaliana

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.0051	-	recombinant enzyme, at pH and °C	Arabidopsis thaliana

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
hydroxypyruvate + NADH + H+	-	Arabidopsis thaliana	D-glycerate + NAD+	-	?

Subunits

Subunits	Comment	Organism
?	x * 42300, calculated from amino acid sequence	Arabidopsis thaliana
?	x * 63500, enzyme with N-terminal choline binding domain, SDS-PAGE	Arabidopsis thaliana

Synonyms

Synonyms	Comment	Organism
HPR1	-	Arabidopsis thaliana
hydroxypyruvate reductase	-	Arabidopsis thaliana

Cofactor

Cofactor	Comment	Organism	Structure
NADH	-	Arabidopsis thaliana

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)