Crystallization (Comment) | Organism |
---|---|
crystals of the binary complex with NAD(H) are grown by a sitting drop vapor diffusion method, where the apoenzyme is equilibrated with a 2 mM NAD+ containing crystallization buffer (0.1 M potassium phosphate, pH 7.1, 12-15% PEG8000, 2 mM DTT, 0.05 mM ZnSO4) | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zinc | contains zinc at the active site | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-(hydroxymethyl)glutathione + NAD+ | Homo sapiens | the enzyme plays an important role in the formaldehyde detoxification and reduction of the nitric oxide metabolite | S-formylglutathione + NADH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
S-(hydroxymethyl)glutathione + NAD+ | the enzyme plays an important role in the formaldehyde detoxification and reduction of the nitric oxide metabolite | Homo sapiens | S-formylglutathione + NADH + H+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Homo sapiens |