BRENDA - Enzyme Database show
show all sequences of 1.1.1.28

Bacterial lactate dehydrogenases

Garvie, E.I.; Microbiol. Rev. 44, 106-139 (1980)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
ADP
-
Enterobacter aerogenes
ADP
-
Escherichia coli
ADP
-
Eubacterium limosum
ADP
-
Lactobacillus acidophilus
ADP
-
Lactobacillus brevis
ADP
-
Lactobacillus buchneri
ADP
-
Lactobacillus casei
ADP
-
Lactobacillus delbrueckii
ADP
-
Lactobacillus delbrueckii subsp. bulgaricus
ADP
-
Lactobacillus delbrueckii subsp. lactis
ADP
-
Lactobacillus fermentum
ADP
-
Lactobacillus jensenii
ADP
-
Lactobacillus jugurt-helveticus
ADP
-
Lactobacillus leichmannii
ADP
-
Lactobacillus plantarum
ADP
-
Lactobacillus vermiforme
ADP
-
Lactococcus lactis
ADP
-
Leuconostoc lactis
ADP
-
Leuconostoc mesenteroides
ADP
-
Leuconostoc mesenteroides subsp. cremoris
ADP
-
Leuconostoc mesenteroides subsp. dextranicum
ADP
-
Mammalia
ADP
-
Mycoplasma sp.
ADP
-
Oenococcus oeni
ADP
-
Pediococcus acidilactici
ADP
-
Pediococcus damnosus
ADP
-
Pediococcus inopinatus
ADP
-
Pediococcus pentosaceus
ADP
-
Selenomonas ruminantium
ADP
-
Staphylococcus aureus
ADP
-
Staphylococcus haemolyticus
ADP
-
Staphylococcus hominis
ADP
-
Staphylococcus sp.
ADP
-
Staphylococcus warneri
ADP
-
Weissella confusa
ADP
-
Weissella paramesenteroides
ADP
-
Weissella viridescens
ATP
-
Enterobacter aerogenes
ATP
-
Escherichia coli
ATP
-
Lactobacillus acidophilus
ATP
-
Lactobacillus brevis
ATP
-
Lactobacillus buchneri
ATP
-
Lactobacillus casei
ATP
-
Lactobacillus delbrueckii
ATP
-
Lactobacillus delbrueckii subsp. bulgaricus
ATP
-
Lactobacillus delbrueckii subsp. lactis
ATP
-
Lactobacillus fermentum
ATP
-
Lactobacillus jensenii
ATP
-
Lactobacillus jugurt-helveticus
ATP
-
Lactobacillus leichmannii
ATP
-
Lactobacillus plantarum
ATP
-
Lactobacillus vermiforme
ATP
-
Lactococcus lactis
ATP
-
Leuconostoc lactis
ATP
-
Leuconostoc mesenteroides
ATP
-
Leuconostoc mesenteroides subsp. cremoris
ATP
-
Leuconostoc mesenteroides subsp. dextranicum
ATP
-
Mammalia
ATP
-
Mycoplasma sp.
ATP
-
Oenococcus oeni
ATP
-
Pediococcus acidilactici
ATP
-
Pediococcus damnosus
ATP
-
Pediococcus inopinatus
ATP
-
Pediococcus pentosaceus
ATP
-
Selenomonas ruminantium
ATP
-
Staphylococcus aureus
ATP
-
Staphylococcus haemolyticus
ATP
-
Staphylococcus hominis
ATP
-
Staphylococcus sp.
ATP
-
Staphylococcus warneri
ATP
-
Weissella confusa
ATP
-
Weissella paramesenteroides
ATP
-
Weissella viridescens
ATP
-
Eubacterium limosum
Cu2+
-
Leuconostoc lactis
Cu2+
-
Pediococcus pentosaceus
Hg2+
-
Leuconostoc lactis
Hg2+
-
Pediococcus pentosaceus
Hg2+
-
Eubacterium limosum
iodoacetamide
-
Enterobacter aerogenes
iodoacetamide
-
Escherichia coli
iodoacetamide
-
Eubacterium limosum
iodoacetamide
-
Lactobacillus acidophilus
iodoacetamide
-
Lactobacillus brevis
iodoacetamide
-
Lactobacillus buchneri
iodoacetamide
-
Lactobacillus casei
iodoacetamide
-
Lactobacillus delbrueckii
iodoacetamide
-
Lactobacillus delbrueckii subsp. bulgaricus
iodoacetamide
-
Lactobacillus delbrueckii subsp. lactis
iodoacetamide
-
Lactobacillus fermentum
iodoacetamide
-
Lactobacillus jensenii
iodoacetamide
-
Lactobacillus jugurt-helveticus
iodoacetamide
-
Lactobacillus leichmannii
iodoacetamide
-
Lactobacillus plantarum
iodoacetamide
-
Lactobacillus vermiforme
iodoacetamide
-
Lactococcus lactis
iodoacetamide
-
Leuconostoc lactis
iodoacetamide
-
Leuconostoc mesenteroides
iodoacetamide
-
Leuconostoc mesenteroides subsp. cremoris
iodoacetamide
-
Leuconostoc mesenteroides subsp. dextranicum
iodoacetamide
-
Mammalia
iodoacetamide
-
Mycoplasma sp.
iodoacetamide
-
Oenococcus oeni
iodoacetamide
-
Pediococcus acidilactici
iodoacetamide
-
Pediococcus damnosus
iodoacetamide
-
Pediococcus inopinatus
iodoacetamide
-
Pediococcus pentosaceus
iodoacetamide
-
Selenomonas ruminantium
iodoacetamide
-
Staphylococcus aureus
iodoacetamide
-
Staphylococcus haemolyticus
iodoacetamide
-
Staphylococcus hominis
iodoacetamide
-
Staphylococcus sp.
iodoacetamide
-
Staphylococcus warneri
iodoacetamide
-
Weissella confusa
iodoacetamide
-
Weissella paramesenteroides
iodoacetamide
-
Weissella viridescens
iodoacetate
-
Enterobacter aerogenes
iodoacetate
-
Escherichia coli
iodoacetate
-
Eubacterium limosum
iodoacetate
-
Lactobacillus acidophilus
iodoacetate
-
Lactobacillus brevis
iodoacetate
-
Lactobacillus buchneri
iodoacetate
-
Lactobacillus casei
iodoacetate
-
Lactobacillus delbrueckii
iodoacetate
-
Lactobacillus delbrueckii subsp. bulgaricus
iodoacetate
-
Lactobacillus delbrueckii subsp. lactis
iodoacetate
-
Lactobacillus fermentum
iodoacetate
-
Lactobacillus jensenii
iodoacetate
-
Lactobacillus jugurt-helveticus
iodoacetate
-
Lactobacillus leichmannii
iodoacetate
-
Lactobacillus plantarum
iodoacetate
-
Lactobacillus vermiforme
iodoacetate
-
Lactococcus lactis
iodoacetate
-
Leuconostoc lactis
iodoacetate
-
Leuconostoc mesenteroides
iodoacetate
-
Leuconostoc mesenteroides subsp. cremoris
iodoacetate
-
Leuconostoc mesenteroides subsp. dextranicum
iodoacetate
-
Mammalia
iodoacetate
-
Mycoplasma sp.
iodoacetate
-
Oenococcus oeni
iodoacetate
-
Pediococcus acidilactici
iodoacetate
-
Pediococcus damnosus
iodoacetate
-
Pediococcus inopinatus
iodoacetate
-
Pediococcus pentosaceus
iodoacetate
-
Selenomonas ruminantium
iodoacetate
-
Staphylococcus aureus
iodoacetate
-
Staphylococcus haemolyticus
iodoacetate
-
Staphylococcus hominis
iodoacetate
-
Staphylococcus sp.
iodoacetate
-
Staphylococcus warneri
iodoacetate
-
Weissella confusa
iodoacetate
-
Weissella paramesenteroides
iodoacetate
-
Weissella viridescens
NAD+
-
Leuconostoc lactis
NAD+
-
Pediococcus pentosaceus
oxalate
-
Lactobacillus delbrueckii subsp. lactis
oxamate
-
Enterobacter aerogenes
oxamate
-
Escherichia coli
oxamate
-
Lactobacillus acidophilus
oxamate
-
Lactobacillus brevis
oxamate
-
Lactobacillus buchneri
oxamate
-
Lactobacillus casei
oxamate
-
Lactobacillus delbrueckii
oxamate
-
Lactobacillus delbrueckii subsp. bulgaricus
oxamate
-
Lactobacillus delbrueckii subsp. lactis
oxamate
-
Lactobacillus fermentum
oxamate
-
Lactobacillus jensenii
oxamate
-
Lactobacillus jugurt-helveticus
oxamate
-
Lactobacillus leichmannii
oxamate
-
Lactobacillus plantarum
oxamate
-
Lactobacillus vermiforme
oxamate
-
Lactococcus lactis
oxamate
-
Leuconostoc lactis
oxamate
-
Leuconostoc mesenteroides
oxamate
-
Leuconostoc mesenteroides subsp. cremoris
oxamate
-
Leuconostoc mesenteroides subsp. dextranicum
oxamate
-
Mammalia
oxamate
-
Mycoplasma sp.
oxamate
-
Oenococcus oeni
oxamate
-
Pediococcus acidilactici
oxamate
-
Pediococcus damnosus
oxamate
-
Pediococcus inopinatus
oxamate
-
Pediococcus pentosaceus
oxamate
-
Selenomonas ruminantium
oxamate
-
Staphylococcus aureus
oxamate
-
Staphylococcus haemolyticus
oxamate
-
Staphylococcus hominis
oxamate
-
Staphylococcus sp.
oxamate
-
Staphylococcus warneri
oxamate
-
Weissella confusa
oxamate
-
Weissella paramesenteroides
oxamate
-
Weissella viridescens
oxamate
-
Eubacterium limosum
p-chloromercuribenzoate
-
Leuconostoc lactis
p-Chloromercuriphenyl sulfonic acid
-
Eubacterium limosum
p-hydroxymercuribenzoate
-
Escherichia coli
Sodium arsenite
-
Escherichia coli
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.001
-
NADH
-
Lactobacillus casei
0.071
-
NADH
-
Lactobacillus plantarum
0.16
-
NADH
-
Lactobacillus acidophilus
1.05
-
NAD+
-
Pediococcus pentosaceus
2.2
-
NAD+
-
Leuconostoc mesenteroides
2.9
-
NAD+
-
Leuconostoc lactis
20
-
(R)-lactate
-
Lactobacillus delbrueckii subsp. lactis
20
-
(R)-lactate
-
Lactobacillus fermentum
70
-
(R)-lactate
-
Lactobacillus jensenii
70
-
(R)-lactate
-
Lactobacillus leichmannii
1250
-
(R)-lactate
-
Lactobacillus acidophilus
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(R)-lactate + NAD+
Mammalia
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus plantarum
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Staphylococcus aureus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Escherichia coli
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Enterobacter aerogenes
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactococcus lactis
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus casei
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Leuconostoc mesenteroides
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Staphylococcus sp.
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus brevis
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus delbrueckii subsp. bulgaricus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus delbrueckii
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus fermentum
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Pediococcus pentosaceus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Staphylococcus haemolyticus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Pediococcus acidilactici
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Leuconostoc lactis
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Selenomonas ruminantium
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus buchneri
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus delbrueckii subsp. lactis
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Oenococcus oeni
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus acidophilus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Leuconostoc mesenteroides subsp. cremoris
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus leichmannii
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Weissella confusa
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus vermiforme
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Weissella viridescens
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Pediococcus damnosus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Pediococcus inopinatus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Mycoplasma sp.
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Eubacterium limosum
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus jensenii
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus jugurt-helveticus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Leuconostoc mesenteroides subsp. dextranicum
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Weissella paramesenteroides
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Staphylococcus hominis
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Staphylococcus warneri
-
pyruvate + NADH
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Enterobacter aerogenes
-
-
-
Escherichia coli
-
-
-
Eubacterium limosum
-
-
-
Lactobacillus acidophilus
-
-
-
Lactobacillus brevis
-
-
-
Lactobacillus buchneri
-
-
-
Lactobacillus casei
-
-
-
Lactobacillus delbrueckii
-
-
-
Lactobacillus delbrueckii subsp. bulgaricus
-
-
-
Lactobacillus delbrueckii subsp. lactis
-
-
-
Lactobacillus fermentum
-
-
-
Lactobacillus jensenii
-
-
-
Lactobacillus jugurt-helveticus
-
-
-
Lactobacillus leichmannii
-
-
-
Lactobacillus plantarum
-
-
-
Lactobacillus vermiforme
-
-
-
Lactococcus lactis
-
-
-
Leuconostoc lactis
-
-
-
Leuconostoc mesenteroides
-
-
-
Leuconostoc mesenteroides subsp. cremoris
-
-
-
Leuconostoc mesenteroides subsp. dextranicum
-
-
-
Mammalia
-
-
-
Mycoplasma sp.
-
-
-
Oenococcus oeni
-
-
-
Pediococcus acidilactici
-
-
-
Pediococcus damnosus
-
-
-
Pediococcus inopinatus
-
-
-
Pediococcus pentosaceus
-
-
-
Selenomonas ruminantium
-
-
-
Staphylococcus aureus
-
-
-
Staphylococcus haemolyticus
-
-
-
Staphylococcus hominis
-
-
-
Staphylococcus sp.
-
-
-
Staphylococcus warneri
-
-
-
Weissella confusa
-
-
-
Weissella paramesenteroides
-
-
-
Weissella viridescens
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(R)-lactate + NAD+
-
286430
Mammalia
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus plantarum
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Staphylococcus aureus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Escherichia coli
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Enterobacter aerogenes
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactococcus lactis
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus casei
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Leuconostoc mesenteroides
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Staphylococcus sp.
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus brevis
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus delbrueckii subsp. bulgaricus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus delbrueckii
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus fermentum
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Pediococcus pentosaceus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Staphylococcus haemolyticus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Pediococcus acidilactici
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Leuconostoc lactis
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Selenomonas ruminantium
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus buchneri
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus delbrueckii subsp. lactis
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Oenococcus oeni
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus acidophilus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Leuconostoc mesenteroides subsp. cremoris
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus leichmannii
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Weissella confusa
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus vermiforme
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Weissella viridescens
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Pediococcus damnosus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Pediococcus inopinatus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Mycoplasma sp.
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Eubacterium limosum
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus jensenii
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus jugurt-helveticus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Leuconostoc mesenteroides subsp. dextranicum
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Weissella paramesenteroides
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Staphylococcus hominis
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Staphylococcus warneri
pyruvate + NADH
-
-
-
?
Temperature Stability [°C]
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
35
-
stable below, Tris-HCl, pH 8.5
Leuconostoc mesenteroides
40
-
stable below, phosphate buffer, pH 7.5
Leuconostoc mesenteroides
45
-
5 min, 98% inactivation
Lactobacillus acidophilus
45
-
3 min, inactivation
Lactobacillus plantarum
45
-
5 min, 98% inactivation
Leuconostoc lactis
50
-
5 min, 98% inactivation
Lactobacillus fermentum
50
-
5 min, 25% loss of activity
Lactobacillus jensenii
50
-
5 min, 50% loss of activity
Lactobacillus leichmannii
50
-
3 min, inactivation
Lactobacillus plantarum
50
-
10 min, inactivation
Staphylococcus haemolyticus
50
-
10 min, inactivation
Staphylococcus hominis
50
-
10 min, inactivation
Staphylococcus warneri
55
-
3 min, inactivation
Pediococcus pentosaceus
80
-
5 min, 100% loss of activity
Lactobacillus jensenii
80
-
5 min, 100% loss of activity
Lactobacillus leichmannii
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.6
-
pH 3.6 or pH 8.0, changes with pyruvate concentration
Pediococcus pentosaceus
6.4
7.5
-
Escherichia coli
6.6
8
-
Leuconostoc lactis
7.3
-
-
Lactobacillus acidophilus
7.6
-
-
Lactobacillus leichmannii
7.8
-
-
Lactobacillus jensenii
8
-
pH 3.6 or pH 8.0, changes with pyruvate concentration
Pediococcus pentosaceus
8.6
-
-
Lactobacillus fermentum
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Enterobacter aerogenes
NAD+
-
Escherichia coli
NAD+
-
Lactobacillus acidophilus
NAD+
-
Lactobacillus brevis
NAD+
-
Lactobacillus buchneri
NAD+
-
Lactobacillus casei
NAD+
-
Lactobacillus delbrueckii
NAD+
-
Lactobacillus delbrueckii subsp. lactis
NAD+
-
Lactobacillus fermentum
NAD+
-
Lactobacillus jugurt-helveticus
NAD+
-
Lactobacillus leichmannii
NAD+
-
Lactobacillus plantarum
NAD+
-
Lactobacillus vermiforme
NAD+
-
Lactococcus lactis
NAD+
-
Leuconostoc lactis
NAD+
-
Leuconostoc mesenteroides
NAD+
-
Leuconostoc mesenteroides subsp. dextranicum
NAD+
-
Mammalia
NAD+
-
Mycoplasma sp.
NAD+
-
Oenococcus oeni
NAD+
-
Pediococcus damnosus
NAD+
-
Pediococcus inopinatus
NAD+
-
Selenomonas ruminantium
NAD+
-
Staphylococcus aureus
NAD+
-
Staphylococcus haemolyticus
NAD+
-
Staphylococcus hominis
NAD+
-
Staphylococcus warneri
NAD+
-
Weissella confusa
NAD+
-
Weissella paramesenteroides
NAD+
-
Weissella viridescens
NAD+
-
Eubacterium limosum
NAD+
-
Leuconostoc mesenteroides subsp. cremoris
NAD+
-
Staphylococcus sp.
NAD+
-
Lactobacillus delbrueckii subsp. bulgaricus
NAD+
-
Pediococcus pentosaceus
NAD+
-
Pediococcus acidilactici
NAD+
-
Lactobacillus jensenii
NADH
-
Enterobacter aerogenes
NADH
-
Escherichia coli
NADH
-
Lactobacillus acidophilus
NADH
-
Lactobacillus brevis
NADH
-
Lactobacillus buchneri
NADH
-
Lactobacillus casei
NADH
-
Lactobacillus delbrueckii
NADH
-
Lactobacillus delbrueckii subsp. lactis
NADH
-
Lactobacillus fermentum
NADH
-
Lactobacillus jugurt-helveticus
NADH
-
Lactobacillus plantarum
NADH
-
Lactobacillus vermiforme
NADH
-
Lactococcus lactis
NADH
-
Leuconostoc lactis
NADH
-
Leuconostoc mesenteroides
NADH
-
Leuconostoc mesenteroides subsp. dextranicum
NADH
-
Mammalia
NADH
-
Mycoplasma sp.
NADH
-
Oenococcus oeni
NADH
-
Pediococcus damnosus
NADH
-
Pediococcus inopinatus
NADH
-
Selenomonas ruminantium
NADH
-
Staphylococcus aureus
NADH
-
Staphylococcus haemolyticus
NADH
-
Staphylococcus hominis
NADH
-
Staphylococcus warneri
NADH
-
Weissella confusa
NADH
-
Weissella paramesenteroides
NADH
-
Weissella viridescens
NADH
-
Eubacterium limosum
NADH
-
Leuconostoc mesenteroides subsp. cremoris
NADH
-
Staphylococcus sp.
NADH
-
Lactobacillus delbrueckii subsp. bulgaricus
NADH
-
Lactobacillus leichmannii
NADH
-
Pediococcus pentosaceus
NADH
-
Pediococcus acidilactici
NADH
-
Lactobacillus jensenii
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Enterobacter aerogenes
NAD+
-
Escherichia coli
NAD+
-
Lactobacillus acidophilus
NAD+
-
Lactobacillus brevis
NAD+
-
Lactobacillus buchneri
NAD+
-
Lactobacillus casei
NAD+
-
Lactobacillus delbrueckii
NAD+
-
Lactobacillus delbrueckii subsp. lactis
NAD+
-
Lactobacillus fermentum
NAD+
-
Lactobacillus jugurt-helveticus
NAD+
-
Lactobacillus leichmannii
NAD+
-
Lactobacillus plantarum
NAD+
-
Lactobacillus vermiforme
NAD+
-
Lactococcus lactis
NAD+
-
Leuconostoc lactis
NAD+
-
Leuconostoc mesenteroides
NAD+
-
Leuconostoc mesenteroides subsp. dextranicum
NAD+
-
Mammalia
NAD+
-
Mycoplasma sp.
NAD+
-
Oenococcus oeni
NAD+
-
Pediococcus damnosus
NAD+
-
Pediococcus inopinatus
NAD+
-
Selenomonas ruminantium
NAD+
-
Staphylococcus aureus
NAD+
-
Staphylococcus haemolyticus
NAD+
-
Staphylococcus hominis
NAD+
-
Staphylococcus warneri
NAD+
-
Weissella confusa
NAD+
-
Weissella paramesenteroides
NAD+
-
Weissella viridescens
NAD+
-
Eubacterium limosum
NAD+
-
Leuconostoc mesenteroides subsp. cremoris
NAD+
-
Staphylococcus sp.
NAD+
-
Lactobacillus delbrueckii subsp. bulgaricus
NAD+
-
Pediococcus pentosaceus
NAD+
-
Pediococcus acidilactici
NAD+
-
Lactobacillus jensenii
NADH
-
Enterobacter aerogenes
NADH
-
Escherichia coli
NADH
-
Lactobacillus acidophilus
NADH
-
Lactobacillus brevis
NADH
-
Lactobacillus buchneri
NADH
-
Lactobacillus casei
NADH
-
Lactobacillus delbrueckii
NADH
-
Lactobacillus delbrueckii subsp. lactis
NADH
-
Lactobacillus fermentum
NADH
-
Lactobacillus jugurt-helveticus
NADH
-
Lactobacillus plantarum
NADH
-
Lactobacillus vermiforme
NADH
-
Lactococcus lactis
NADH
-
Leuconostoc lactis
NADH
-
Leuconostoc mesenteroides
NADH
-
Leuconostoc mesenteroides subsp. dextranicum
NADH
-
Mammalia
NADH
-
Mycoplasma sp.
NADH
-
Oenococcus oeni
NADH
-
Pediococcus damnosus
NADH
-
Pediococcus inopinatus
NADH
-
Selenomonas ruminantium
NADH
-
Staphylococcus aureus
NADH
-
Staphylococcus haemolyticus
NADH
-
Staphylococcus hominis
NADH
-
Staphylococcus warneri
NADH
-
Weissella confusa
NADH
-
Weissella paramesenteroides
NADH
-
Weissella viridescens
NADH
-
Eubacterium limosum
NADH
-
Leuconostoc mesenteroides subsp. cremoris
NADH
-
Staphylococcus sp.
NADH
-
Lactobacillus delbrueckii subsp. bulgaricus
NADH
-
Lactobacillus leichmannii
NADH
-
Pediococcus pentosaceus
NADH
-
Pediococcus acidilactici
NADH
-
Lactobacillus jensenii
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
ADP
-
Enterobacter aerogenes
ADP
-
Escherichia coli
ADP
-
Eubacterium limosum
ADP
-
Lactobacillus acidophilus
ADP
-
Lactobacillus brevis
ADP
-
Lactobacillus buchneri
ADP
-
Lactobacillus casei
ADP
-
Lactobacillus delbrueckii
ADP
-
Lactobacillus delbrueckii subsp. bulgaricus
ADP
-
Lactobacillus delbrueckii subsp. lactis
ADP
-
Lactobacillus fermentum
ADP
-
Lactobacillus jensenii
ADP
-
Lactobacillus jugurt-helveticus
ADP
-
Lactobacillus leichmannii
ADP
-
Lactobacillus plantarum
ADP
-
Lactobacillus vermiforme
ADP
-
Lactococcus lactis
ADP
-
Leuconostoc lactis
ADP
-
Leuconostoc mesenteroides
ADP
-
Leuconostoc mesenteroides subsp. cremoris
ADP
-
Leuconostoc mesenteroides subsp. dextranicum
ADP
-
Mammalia
ADP
-
Mycoplasma sp.
ADP
-
Oenococcus oeni
ADP
-
Pediococcus acidilactici
ADP
-
Pediococcus damnosus
ADP
-
Pediococcus inopinatus
ADP
-
Pediococcus pentosaceus
ADP
-
Selenomonas ruminantium
ADP
-
Staphylococcus aureus
ADP
-
Staphylococcus haemolyticus
ADP
-
Staphylococcus hominis
ADP
-
Staphylococcus sp.
ADP
-
Staphylococcus warneri
ADP
-
Weissella confusa
ADP
-
Weissella paramesenteroides
ADP
-
Weissella viridescens
ATP
-
Enterobacter aerogenes
ATP
-
Escherichia coli
ATP
-
Lactobacillus acidophilus
ATP
-
Lactobacillus brevis
ATP
-
Lactobacillus buchneri
ATP
-
Lactobacillus casei
ATP
-
Lactobacillus delbrueckii
ATP
-
Lactobacillus delbrueckii subsp. bulgaricus
ATP
-
Lactobacillus delbrueckii subsp. lactis
ATP
-
Lactobacillus fermentum
ATP
-
Lactobacillus jensenii
ATP
-
Lactobacillus jugurt-helveticus
ATP
-
Lactobacillus leichmannii
ATP
-
Lactobacillus plantarum
ATP
-
Lactobacillus vermiforme
ATP
-
Lactococcus lactis
ATP
-
Leuconostoc lactis
ATP
-
Leuconostoc mesenteroides
ATP
-
Leuconostoc mesenteroides subsp. cremoris
ATP
-
Leuconostoc mesenteroides subsp. dextranicum
ATP
-
Mammalia
ATP
-
Mycoplasma sp.
ATP
-
Oenococcus oeni
ATP
-
Pediococcus acidilactici
ATP
-
Pediococcus damnosus
ATP
-
Pediococcus inopinatus
ATP
-
Pediococcus pentosaceus
ATP
-
Selenomonas ruminantium
ATP
-
Staphylococcus aureus
ATP
-
Staphylococcus haemolyticus
ATP
-
Staphylococcus hominis
ATP
-
Staphylococcus sp.
ATP
-
Staphylococcus warneri
ATP
-
Weissella confusa
ATP
-
Weissella paramesenteroides
ATP
-
Weissella viridescens
ATP
-
Eubacterium limosum
Cu2+
-
Leuconostoc lactis
Cu2+
-
Pediococcus pentosaceus
Hg2+
-
Leuconostoc lactis
Hg2+
-
Pediococcus pentosaceus
Hg2+
-
Eubacterium limosum
iodoacetamide
-
Enterobacter aerogenes
iodoacetamide
-
Escherichia coli
iodoacetamide
-
Eubacterium limosum
iodoacetamide
-
Lactobacillus acidophilus
iodoacetamide
-
Lactobacillus brevis
iodoacetamide
-
Lactobacillus buchneri
iodoacetamide
-
Lactobacillus casei
iodoacetamide
-
Lactobacillus delbrueckii
iodoacetamide
-
Lactobacillus delbrueckii subsp. bulgaricus
iodoacetamide
-
Lactobacillus delbrueckii subsp. lactis
iodoacetamide
-
Lactobacillus fermentum
iodoacetamide
-
Lactobacillus jensenii
iodoacetamide
-
Lactobacillus jugurt-helveticus
iodoacetamide
-
Lactobacillus leichmannii
iodoacetamide
-
Lactobacillus plantarum
iodoacetamide
-
Lactobacillus vermiforme
iodoacetamide
-
Lactococcus lactis
iodoacetamide
-
Leuconostoc lactis
iodoacetamide
-
Leuconostoc mesenteroides
iodoacetamide
-
Leuconostoc mesenteroides subsp. cremoris
iodoacetamide
-
Leuconostoc mesenteroides subsp. dextranicum
iodoacetamide
-
Mammalia
iodoacetamide
-
Mycoplasma sp.
iodoacetamide
-
Oenococcus oeni
iodoacetamide
-
Pediococcus acidilactici
iodoacetamide
-
Pediococcus damnosus
iodoacetamide
-
Pediococcus inopinatus
iodoacetamide
-
Pediococcus pentosaceus
iodoacetamide
-
Selenomonas ruminantium
iodoacetamide
-
Staphylococcus aureus
iodoacetamide
-
Staphylococcus haemolyticus
iodoacetamide
-
Staphylococcus hominis
iodoacetamide
-
Staphylococcus sp.
iodoacetamide
-
Staphylococcus warneri
iodoacetamide
-
Weissella confusa
iodoacetamide
-
Weissella paramesenteroides
iodoacetamide
-
Weissella viridescens
iodoacetate
-
Enterobacter aerogenes
iodoacetate
-
Escherichia coli
iodoacetate
-
Eubacterium limosum
iodoacetate
-
Lactobacillus acidophilus
iodoacetate
-
Lactobacillus brevis
iodoacetate
-
Lactobacillus buchneri
iodoacetate
-
Lactobacillus casei
iodoacetate
-
Lactobacillus delbrueckii
iodoacetate
-
Lactobacillus delbrueckii subsp. bulgaricus
iodoacetate
-
Lactobacillus delbrueckii subsp. lactis
iodoacetate
-
Lactobacillus fermentum
iodoacetate
-
Lactobacillus jensenii
iodoacetate
-
Lactobacillus jugurt-helveticus
iodoacetate
-
Lactobacillus leichmannii
iodoacetate
-
Lactobacillus plantarum
iodoacetate
-
Lactobacillus vermiforme
iodoacetate
-
Lactococcus lactis
iodoacetate
-
Leuconostoc lactis
iodoacetate
-
Leuconostoc mesenteroides
iodoacetate
-
Leuconostoc mesenteroides subsp. cremoris
iodoacetate
-
Leuconostoc mesenteroides subsp. dextranicum
iodoacetate
-
Mammalia
iodoacetate
-
Mycoplasma sp.
iodoacetate
-
Oenococcus oeni
iodoacetate
-
Pediococcus acidilactici
iodoacetate
-
Pediococcus damnosus
iodoacetate
-
Pediococcus inopinatus
iodoacetate
-
Pediococcus pentosaceus
iodoacetate
-
Selenomonas ruminantium
iodoacetate
-
Staphylococcus aureus
iodoacetate
-
Staphylococcus haemolyticus
iodoacetate
-
Staphylococcus hominis
iodoacetate
-
Staphylococcus sp.
iodoacetate
-
Staphylococcus warneri
iodoacetate
-
Weissella confusa
iodoacetate
-
Weissella paramesenteroides
iodoacetate
-
Weissella viridescens
NAD+
-
Leuconostoc lactis
NAD+
-
Pediococcus pentosaceus
oxalate
-
Lactobacillus delbrueckii subsp. lactis
oxamate
-
Enterobacter aerogenes
oxamate
-
Escherichia coli
oxamate
-
Lactobacillus acidophilus
oxamate
-
Lactobacillus brevis
oxamate
-
Lactobacillus buchneri
oxamate
-
Lactobacillus casei
oxamate
-
Lactobacillus delbrueckii
oxamate
-
Lactobacillus delbrueckii subsp. bulgaricus
oxamate
-
Lactobacillus delbrueckii subsp. lactis
oxamate
-
Lactobacillus fermentum
oxamate
-
Lactobacillus jensenii
oxamate
-
Lactobacillus jugurt-helveticus
oxamate
-
Lactobacillus leichmannii
oxamate
-
Lactobacillus plantarum
oxamate
-
Lactobacillus vermiforme
oxamate
-
Lactococcus lactis
oxamate
-
Leuconostoc lactis
oxamate
-
Leuconostoc mesenteroides
oxamate
-
Leuconostoc mesenteroides subsp. cremoris
oxamate
-
Leuconostoc mesenteroides subsp. dextranicum
oxamate
-
Mammalia
oxamate
-
Mycoplasma sp.
oxamate
-
Oenococcus oeni
oxamate
-
Pediococcus acidilactici
oxamate
-
Pediococcus damnosus
oxamate
-
Pediococcus inopinatus
oxamate
-
Pediococcus pentosaceus
oxamate
-
Selenomonas ruminantium
oxamate
-
Staphylococcus aureus
oxamate
-
Staphylococcus haemolyticus
oxamate
-
Staphylococcus hominis
oxamate
-
Staphylococcus sp.
oxamate
-
Staphylococcus warneri
oxamate
-
Weissella confusa
oxamate
-
Weissella paramesenteroides
oxamate
-
Weissella viridescens
oxamate
-
Eubacterium limosum
p-chloromercuribenzoate
-
Leuconostoc lactis
p-Chloromercuriphenyl sulfonic acid
-
Eubacterium limosum
p-hydroxymercuribenzoate
-
Escherichia coli
Sodium arsenite
-
Escherichia coli
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.001
-
NADH
-
Lactobacillus casei
0.071
-
NADH
-
Lactobacillus plantarum
0.16
-
NADH
-
Lactobacillus acidophilus
1.05
-
NAD+
-
Pediococcus pentosaceus
2.2
-
NAD+
-
Leuconostoc mesenteroides
2.9
-
NAD+
-
Leuconostoc lactis
20
-
(R)-lactate
-
Lactobacillus delbrueckii subsp. lactis
20
-
(R)-lactate
-
Lactobacillus fermentum
70
-
(R)-lactate
-
Lactobacillus jensenii
70
-
(R)-lactate
-
Lactobacillus leichmannii
1250
-
(R)-lactate
-
Lactobacillus acidophilus
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(R)-lactate + NAD+
Mammalia
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus plantarum
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Staphylococcus aureus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Escherichia coli
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Enterobacter aerogenes
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactococcus lactis
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus casei
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Leuconostoc mesenteroides
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Staphylococcus sp.
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus brevis
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus delbrueckii subsp. bulgaricus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus delbrueckii
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus fermentum
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Pediococcus pentosaceus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Staphylococcus haemolyticus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Pediococcus acidilactici
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Leuconostoc lactis
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Selenomonas ruminantium
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus buchneri
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus delbrueckii subsp. lactis
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Oenococcus oeni
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus acidophilus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Leuconostoc mesenteroides subsp. cremoris
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus leichmannii
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Weissella confusa
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus vermiforme
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Weissella viridescens
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Pediococcus damnosus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Pediococcus inopinatus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Mycoplasma sp.
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Eubacterium limosum
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus jensenii
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Lactobacillus jugurt-helveticus
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Leuconostoc mesenteroides subsp. dextranicum
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Weissella paramesenteroides
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Staphylococcus hominis
-
pyruvate + NADH
-
-
?
(R)-lactate + NAD+
Staphylococcus warneri
-
pyruvate + NADH
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(R)-lactate + NAD+
-
286430
Mammalia
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus plantarum
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Staphylococcus aureus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Escherichia coli
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Enterobacter aerogenes
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactococcus lactis
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus casei
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Leuconostoc mesenteroides
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Staphylococcus sp.
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus brevis
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus delbrueckii subsp. bulgaricus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus delbrueckii
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus fermentum
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Pediococcus pentosaceus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Staphylococcus haemolyticus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Pediococcus acidilactici
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Leuconostoc lactis
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Selenomonas ruminantium
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus buchneri
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus delbrueckii subsp. lactis
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Oenococcus oeni
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus acidophilus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Leuconostoc mesenteroides subsp. cremoris
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus leichmannii
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Weissella confusa
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus vermiforme
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Weissella viridescens
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Pediococcus damnosus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Pediococcus inopinatus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Mycoplasma sp.
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Eubacterium limosum
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus jensenii
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Lactobacillus jugurt-helveticus
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Leuconostoc mesenteroides subsp. dextranicum
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Weissella paramesenteroides
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Staphylococcus hominis
pyruvate + NADH
-
-
-
?
(R)-lactate + NAD+
-
286430
Staphylococcus warneri
pyruvate + NADH
-
-
-
?
Temperature Stability [°C] (protein specific)
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
35
-
stable below, Tris-HCl, pH 8.5
Leuconostoc mesenteroides
40
-
stable below, phosphate buffer, pH 7.5
Leuconostoc mesenteroides
45
-
5 min, 98% inactivation
Lactobacillus acidophilus
45
-
3 min, inactivation
Lactobacillus plantarum
45
-
5 min, 98% inactivation
Leuconostoc lactis
50
-
5 min, 98% inactivation
Lactobacillus fermentum
50
-
5 min, 25% loss of activity
Lactobacillus jensenii
50
-
5 min, 50% loss of activity
Lactobacillus leichmannii
50
-
3 min, inactivation
Lactobacillus plantarum
50
-
10 min, inactivation
Staphylococcus haemolyticus
50
-
10 min, inactivation
Staphylococcus hominis
50
-
10 min, inactivation
Staphylococcus warneri
55
-
3 min, inactivation
Pediococcus pentosaceus
80
-
5 min, 100% loss of activity
Lactobacillus jensenii
80
-
5 min, 100% loss of activity
Lactobacillus leichmannii
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
3.6
-
pH 3.6 or pH 8.0, changes with pyruvate concentration
Pediococcus pentosaceus
6.4
7.5
-
Escherichia coli
6.6
8
-
Leuconostoc lactis
7.3
-
-
Lactobacillus acidophilus
7.6
-
-
Lactobacillus leichmannii
7.8
-
-
Lactobacillus jensenii
8
-
pH 3.6 or pH 8.0, changes with pyruvate concentration
Pediococcus pentosaceus
8.6
-
-
Lactobacillus fermentum
Other publictions for EC 1.1.1.28
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
723678
Jun
-
Discovery and characterization ...
Lactobacillus jensenii
Process Biochem.
48
109-117
2013
-
-
1
-
-
-
-
6
-
-
-
1
-
1
-
-
-
-
-
-
15
-
6
-
2
2
4
6
2
2
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
6
-
-
-
1
-
-
-
-
-
-
15
-
6
-
2
2
4
6
2
2
-
-
-
-
-
-
6
6
721879
Yu
Characterization of D-lactate ...
Pediococcus pentosaceus, Pediococcus pentosaceus ATCC 25745
Biosci. Biotechnol. Biochem.
76
853-855
2012
-
-
-
-
-
-
3
2
-
4
1
4
-
4
-
-
-
-
-
-
2
-
4
1
1
1
1
2
1
1
-
2
-
-
-
-
-
-
2
-
-
-
-
3
-
2
-
4
1
4
-
-
-
-
-
-
2
-
4
1
1
1
1
2
1
1
-
-
-
-
-
-
2
2
721909
Mu
Characterization of D-lactate ...
Pediococcus acidilactici, Pediococcus acidilactici DSM 20284
Biotechnol. Lett.
34
907-911
2012
-
-
1
-
-
-
2
2
-
2
1
4
-
2
-
-
1
-
-
-
2
-
4
1
1
1
1
1
1
1
-
2
-
-
-
-
-
1
2
-
-
-
-
2
-
2
-
2
1
4
-
-
-
1
-
-
2
-
4
1
1
1
1
1
1
1
-
-
-
-
-
-
2
2
722140
Li
Characterization of the major ...
Leuconostoc mesenteroides subsp. mesenteroides, Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293
Enzyme Microb. Technol.
51
274-279
2012
-
-
1
-
-
-
3
4
-
-
-
2
-
7
-
-
1
-
-
-
3
-
2
1
2
1
-
2
2
2
-
2
-
-
-
-
-
1
2
-
-
-
-
3
-
4
-
-
-
2
-
-
-
1
-
-
3
-
2
1
2
1
-
2
2
2
-
-
-
-
-
-
-
-
722283
Wienstroer
D-Lactate dehydrogenase as a m ...
Arabidopsis thaliana, Arabidopsis thaliana Columbia-0
FEBS Lett.
586
36-40
2012
-
1
-
-
1
-
-
-
-
-
-
2
-
5
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
1
-
2
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
721200
Shibahara
Crystallization and preliminar ...
Aeropyrum pernix
Acta Crystallogr. Sect. F
67
1425-1427
2011
-
-
1
1
-
-
-
-
-
-
2
2
-
1
-
-
1
-
-
-
-
-
2
1
-
-
-
-
-
-
-
2
-
-
-
-
-
1
2
1
-
-
-
-
-
-
-
-
2
2
-
-
-
1
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
701818
Okano
Improved production of homo-D- ...
Lactobacillus plantarum, Lactobacillus plantarum NCIMB 8826
Appl. Environ. Microbiol.
75
7858-7861
2009
-
-
-
-
1
-
-
-
-
-
-
3
-
4
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
710727
Antonyuk
Structure of D-lactate dehydro ...
Aquifex aeolicus
Acta Crystallogr. Sect. F
65
1209-1213
2009
-
-
1
1
-
-
-
-
-
-
-
1
-
3
-
-
1
-
-
-
-
-
3
1
-
-
-
-
-
-
-
3
-
-
-
-
-
1
3
1
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
3
1
-
-
-
-
-
-
-
-
-
1
1
-
-
-
684633
Okino
Production of D-lactic acid by ...
Escherichia coli, Lactobacillus delbrueckii
Appl. Microbiol. Biotechnol.
78
449-454
2008
-
-
2
-
-
-
-
-
-
4
-
2
-
5
-
-
-
-
-
-
2
-
4
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
4
-
2
-
-
-
-
-
-
2
-
4
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
695707
Xu
Breeding of D(-)-lactic acid h ...
Sporolactobacillus sp., Sporolactobacillus sp. DX12
Appl. Biochem. Biotechnol.
160
314-321
2008
-
-
-
-
1
-
-
-
-
-
-
2
-
2
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
688878
Mazzei
-
Peroxidase based biosensors fo ...
Staphylococcus epidermidis
Microchem. J.
87
81-86
2007
-
1
-
-
1
-
-
-
-
1
-
1
-
1
-
-
-
-
-
1
1
-
1
-
1
-
-
-
1
-
-
2
-
-
-
-
1
-
2
-
1
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
1
-
1
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
667751
Minenko
Use of the addressing sequence ...
Saccharomyces cerevisiae
Biochemistry
71
32-38
2006
-
-
1
-
-
-
-
-
2
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
669543
Ishida
D-lactic acid production by me ...
Leuconostoc mesenteroides
J. Biosci. Bioeng.
101
172-177
2006
-
1
1
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
665878
Fujisawa
-
D-lactate metabolism in starve ...
Octopus ocellatus
J. Exp. Zool. A
303A
489-496
2005
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
668233
Findrik
-
Modelling and optimization of ...
Lactobacillus leichmannii
Chem. Biochem. Eng. Q.
19
351-358
2005
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
669152
Ishikura
Recognition site for the side ...
Lactobacillus pentosus
J. Biochem.
138
741-749
2005
-
-
-
-
9
-
-
46
-
-
-
-
-
2
-
-
-
-
-
-
-
-
10
-
-
-
-
46
-
-
-
1
-
-
-
-
-
-
1
-
9
-
-
-
-
46
-
-
-
-
-
-
-
-
-
-
-
-
10
-
-
-
-
46
-
-
-
-
-
-
-
-
-
-
669327
Shinoda
Distinct conformation-mediated ...
Lactobacillus pentosus
J. Biol. Chem.
280
17068-17075
2005
-
-
-
1
-
-
2
8
-
-
-
-
-
3
-
-
-
-
-
-
-
-
4
-
-
-
-
8
-
-
-
-
4
-
-
-
-
-
-
1
-
-
-
2
4
8
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
670130
Zhu
Effect of a single-gene knocko ...
Escherichia coli
Metab. Eng.
7
104-115
2005
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
654456
Hachiya
Interaction of D-lactate dehyd ...
Saccharomyces cerevisiae
Biochem. Biophys. Res. Commun.
319
78-82
2004
-
-
-
-
1
-
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
655064
Horikiri
Electron acquisition system co ...
Rhodopseudomonas palustris
Biosci. Biotechnol. Biochem.
68
516-522
2004
-
-
-
-
-
-
1
1
-
-
2
-
-
3
-
-
1
-
-
-
1
-
3
1
1
-
2
-
1
-
-
2
1
1
-
-
-
-
2
-
-
-
-
1
1
1
-
-
2
-
-
-
-
1
-
-
1
-
3
1
1
-
2
-
1
-
-
1
-
-
-
-
-
-
656426
Iino
The effect of sodium acetate o ...
Lactobacillus plantarum, Lactobacillus plantarum NRIC 1067T, Lactobacillus sakei, Lactobacillus sakei NRIC 1071T
J. Gen. Appl. Microbiol.
49
51-58
2003
-
-
-
-
-
-
-
-
2
-
-
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
656314
Isobe
Crystallization and some prope ...
Staphylococcus sp., Staphylococcus sp. LDH-1
J. Biosci. Bioeng.
94
330-335
2002
-
-
-
-
-
-
3
4
-
-
2
-
-
3
-
-
1
-
-
-
1
-
11
2
1
1
-
-
2
-
1
2
-
-
-
-
-
-
2
-
-
-
-
3
-
4
-
-
2
-
-
-
-
1
-
-
1
-
11
2
1
1
-
-
2
-
1
-
-
-
-
-
-
-
656500
Razeto
Domain closure, substrate spec ...
Lactobacillus delbrueckii subsp. bulgaricus
J. Mol. Biol.
318
109-119
2002
-
-
-
1
1
-
-
-
-
-
-
-
-
3
-
-
-
1
-
-
-
-
2
-
-
-
-
-
2
-
-
2
-
-
-
-
-
-
2
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
286501
Kochhar
Roles of His205, His296, His30 ...
Lactobacillus delbrueckii subsp. bulgaricus
Eur. J. Biochem.
267
1633-1639
2000
-
-
-
-
4
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286502
Dym
The crystal structure of D-lac ...
Escherichia coli
Proc. Natl. Acad. Sci. USA
97
9413-9418
2000
-
-
-
1
-
-
-
-
3
-
-
1
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
1
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286500
Stoll
A thioredoxin fusion protein o ...
Enterococcus faecium
Protein Sci.
7
1147-1155
1998
3
-
1
1
-
-
-
3
-
-
-
1
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
3
-
1
2
1
-
-
-
-
-
3
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286499
Dartois
Purification, properties and D ...
Leuconostoc mesenteroides subsp. cremoris
Res. Microbiol.
146
291-302
1995
-
-
1
-
-
-
-
4
-
-
1
1
-
4
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
2
-
-
-
-
-
1
2
-
-
-
-
-
-
4
-
-
1
1
-
-
-
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286503
Nessler
Crystallization of D-lactate d ...
Lactobacillus delbrueckii subsp. bulgaricus
J. Mol. Biol.
235
370-371
1994
-
-
-
1
-
-
-
-
-
-
-
1
-
2
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286498
Erwin
Oxidation of D-lactate and L-l ...
Neisseria meningitidis
J. Bacteriol.
175
6382-6391
1993
-
-
1
-
-
-
9
1
1
2
1
1
-
3
-
-
1
-
-
-
-
-
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
1
2
-
-
-
-
9
-
1
1
2
1
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
286496
Kochhar
Primary structure, physicochem ...
Lactobacillus delbrueckii subsp. bulgaricus
J. Biol. Chem.
267
8499-8513
1992
-
-
-
-
-
-
-
-
-
-
1
1
-
2
-
-
1
-
-
-
-
-
1
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
1
-
-
-
-
1
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
286497
Kochhar
Cloning and overexpression of ...
Lactobacillus delbrueckii subsp. bulgaricus
Biochem. Biophys. Res. Commun.
185
705-712
1992
-
-
1
-
-
-
-
2
-
-
1
1
-
5
-
-
1
-
-
-
1
-
2
1
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
2
-
-
1
1
-
-
-
1
-
-
1
-
2
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
286504
Kochhar
Glutamate 264 modulates the pH ...
Lactobacillus delbrueckii subsp. bulgaricus
J. Biol. Chem.
267
20298-20301
1992
-
-
1
-
1
-
-
4
-
-
-
1
-
3
-
-
1
-
-
-
-
-
4
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
4
-
-
-
1
-
-
-
1
-
-
-
-
4
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
659546
Schmidt
Optimization of a process for ...
Staphylococcus epidermidis
J. Biotechnol.
24
315-327
1992
-
1
-
-
-
1
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
1
-
-
-
1
-
-
1
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
286495
Le Bras
Properties of D-lactate dehydr ...
Lactobacillus delbrueckii subsp. bulgaricus
FEMS Microbiol. Lett.
79
89-93
1991
-
-
-
-
-
-
-
2
-
-
2
1
-
2
-
-
1
-
-
-
1
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
2
1
-
-
-
1
-
-
1
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286483
Jaenicke
-
Dimeric lactic dehydrogenase f ...
Cardium edule
Naturwissenschaften
68
205-206
1981
-
-
-
-
-
-
-
-
-
-
2
1
-
1
-
-
-
-
-
2
-
-
1
1
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
2
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286430
Garvie
Bacterial lactate dehydrogenas ...
Enterobacter aerogenes, Escherichia coli, Eubacterium limosum, Lactobacillus acidophilus, Lactobacillus brevis, Lactobacillus buchneri, Lactobacillus casei, Lactobacillus delbrueckii, Lactobacillus delbrueckii subsp. bulgaricus, Lactobacillus delbrueckii subsp. lactis, Lactobacillus fermentum, Lactobacillus jensenii, Lactobacillus jugurt-helveticus, Lactobacillus leichmannii, Lactobacillus plantarum, Lactobacillus vermiforme, Lactococcus lactis, Leuconostoc lactis, Leuconostoc mesenteroides, Leuconostoc mesenteroides subsp. cremoris, Leuconostoc mesenteroides subsp. dextranicum, Mammalia, Mycoplasma sp., Oenococcus oeni, Pediococcus acidilactici, Pediococcus damnosus, Pediococcus inopinatus, Pediococcus pentosaceus, Selenomonas ruminantium, Staphylococcus aureus, Staphylococcus haemolyticus, Staphylococcus hominis, Staphylococcus sp., Staphylococcus warneri, Weissella confusa, Weissella paramesenteroides, Weissella viridescens
Microbiol. Rev.
44
106-139
1980
-
-
-
-
-
-
197
11
-
-
-
37
-
37
-
-
-
-
-
-
-
-
37
-
-
-
15
-
8
-
-
74
-
-
-
-
-
-
74
-
-
-
-
197
-
11
-
-
-
37
-
-
-
-
-
-
-
-
37
-
-
-
15
-
8
-
-
-
-
-
-
-
-
-
286489
Long
-
Comparative enzymology and phy ...
Haliotis cracherodii, Helix aspersa
J. Exp. Zool.
207
237-248
1979
-
-
-
-
-
-
2
10
-
-
-
2
-
2
-
-
2
-
-
2
-
-
4
2
-
-
-
-
4
-
-
4
-
-
-
-
-
-
4
-
-
-
-
2
-
10
-
-
-
2
-
-
-
2
-
2
-
-
4
2
-
-
-
-
4
-
-
-
-
-
-
-
-
-
286488
Storey
Lactate dehydrogenase in tissu ...
Helix aspersa
Comp. Biochem. Physiol. B
56
181-187
1977
-
-
-
-
-
-
1
4
-
-
2
1
-
2
-
-
-
-
-
5
-
-
1
1
-
-
-
-
2
-
-
2
-
-
-
-
-
-
2
-
-
-
-
1
-
4
-
-
2
1
-
-
-
-
-
5
-
-
1
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
286484
LeJohn
D(-)-lactate dehydrogenase fro ...
Phytophthora undulata, Pythium debaryanum, Sapromyces elongatus
Methods Enzymol.
41B
293-298
1975
3
-
-
-
-
-
-
-
-
-
2
3
-
3
-
-
3
3
-
3
-
6
3
-
-
-
-
-
-
-
-
6
-
-
-
3
-
-
6
-
-
-
-
-
-
-
-
-
2
3
-
-
-
3
-
3
-
6
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286490
Wittenberger
D(-)-Lactate dehydrogenase fro ...
Eubacterium limosum
Methods Enzymol.
41B
299-303
1975
-
-
-
-
-
1
4
-
-
-
1
1
-
1
-
-
1
-
-
-
-
1
1
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
1
-
4
-
-
-
-
1
1
-
-
-
1
-
-
-
1
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
286491
Long
D-Lactate dehydrogenase from t ...
Limulus polyphemus
Methods Enzymol.
41B
313-323
1975
-
-
-
-
-
1
4
4
-
-
2
1
-
1
-
-
1
-
-
1
-
-
1
1
-
-
2
1
-
-
-
2
-
-
-
-
-
-
2
-
-
1
-
4
-
4
-
-
2
1
-
-
-
1
-
1
-
-
1
1
-
-
2
1
-
-
-
-
-
-
-
-
-
-
286492
Long
Diphosphopyridine nucleotide-l ...
Limulus polyphemus, Neanthes virens
Arch. Biochem. Biophys.
154
696-710
1973
-
-
-
-
-
-
2
-
-
-
2
2
-
2
-
-
2
-
-
-
-
-
2
1
-
-
-
-
-
-
-
4
-
-
-
-
-
-
4
-
-
-
-
2
-
-
-
-
2
2
-
-
-
2
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286493
Purohit
D(-)-lactate dehydrogenase fro ...
Allomyces sp.
Arch. Mikrobiol.
84
287-300
1972
-
-
-
-
-
1
2
-
-
-
-
1
-
1
-
-
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
1
-
2
-
-
-
-
-
1
-
-
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286485
Garland
Salt-induced alteration of D(- ...
Polysphondylium pallidum
Biochem. Biophys. Res. Commun.
26
679-685
1967
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286486
Wolin
Fructose-1,6-diphosphate requi ...
Streptococcus equinus
Science
146
775-776
1964
1
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286487
Pascal
-
Sur la configuration du lactat ...
Enterobacter aerogenes
Ann. Inst. Pasteur (Paris)
107
55-62
1964
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-