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Literature summary for 1.1.1.271 extracted from

  • Moriwaki, K.; Noda, K.; Nakagawa, T.; Asahi, M.; Yoshihara, H.; Taniguchi, N.; Hayashi, N.; Miyoshi, E.
    A high expression of GDP-fucose transporter in hepatocellular carcinoma is a key factor for increases in fucosylation (2007), Glycobiology, 17, 1311-1320.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
quantitative RT-PCR expression analysis of the enzyme in liver and hepatocarcinomas, overview Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
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 Homo sapiens 5829
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens fucosylation is regulated by complicated mechanisms that involve several factors: fucosyltransferases, GDP-fucose transporter, and GDP-fucose-synthetic enzymes, such as GDP-mannose 4,6-dehydratase, GDP-4-keto-6-deoxy-mannose-3,5-epimerase-4-reductase, and GDP-fucose pyrophosphorylase, fucose metabolism, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
hepatocellular carcinoma cell increased enzyme expression compared with adjacent tissue or the tissue of healthy livers, quantitative RT-PCR expression analysis, overview Homo sapiens
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liver
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 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information fucosylation is regulated by complicated mechanisms that involve several factors: fucosyltransferases, GDP-fucose transporter, and GDP-fucose-synthetic enzymes, such as GDP-mannose 4,6-dehydratase, GDP-4-keto-6-deoxy-mannose-3,5-epimerase-4-reductase, and GDP-fucose pyrophosphorylase, fucose metabolism, overview Homo sapiens ?
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 ?

Synonyms

Synonyms Comment Organism
GDP-4-keto-6-deoxy-mannose-3,5-epimerase-4-reductase
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 Homo sapiens