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Literature summary for 1.1.1.267 extracted from

  • Cordoba, E.; Salmi, M.; Leon, P.
    Unravelling the regulatory mechanisms that modulate the MEP pathway in higher plants (2009), J. Exp. Bot., 60, 2933-2943.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information transcript accumulation of DXR gene is regulated by mechanical wounding and fungal elicitors. Expression of the DXR gene in rubber trees is not induced by light Hevea brasiliensis

Application

Application Comment Organism
biotechnology DXR plays a role in the methyl-D-erythritol 4-phosphate pathway, which is responsible for the biosynthesis of a substantial number of natural compounds of biological and biotechnological importance and is considered as a target to develop new herbicides and antimicrobial drugs Hevea brasiliensis

Organism

Organism UniProt Comment Textmining
Hevea brasiliensis
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information RIF10 and RIF1 mutants with defects in plastid RNA processing, protein accumulation, and protein degradation, accumulate higher levels of DXR Hevea brasiliensis
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-deoxy-D-xylulose 5-phosphate + NAD(P)H + H+
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Hevea brasiliensis 2-C-methyl-D-erythritol 4-phosphate + NAD(P)+
-
?
additional information DXR has rate-limiting roles in isopentenyl diphosphate and dimethylallyl diphosphate synthesis Hevea brasiliensis ?
-
?

Synonyms

Synonyms Comment Organism
DXP reductoisomerase
-
Hevea brasiliensis
DXR
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Hevea brasiliensis
DXR1
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Hevea brasiliensis

Cofactor

Cofactor Comment Organism Structure
NAD(P)H
-
Hevea brasiliensis