Cloned (Comment) | Organism |
---|---|
phylogenetic analysis | Methanosarcina barkeri |
phylogenetic analysis | Pyrococcus sp. |
phylogenetic analysis | Methanothermobacter thermautotrophicus |
phylogenetic analysis | Pyrococcus furiosus |
phylogenetic analysis | Halobacterium salinarum |
phylogenetic analysis | Thermoplasma acidophilum |
phylogenetic analysis | Aeropyrum pernix |
phylogenetic analysis | Sulfurisphaera tokodaii |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | kinetic analysis | Aeropyrum pernix |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | required | Methanosarcina barkeri | |
Zn2+ | required | Pyrococcus sp. | |
Zn2+ | required | Methanothermobacter thermautotrophicus | |
Zn2+ | required | Pyrococcus furiosus | |
Zn2+ | required | Halobacterium salinarum | |
Zn2+ | required | Thermoplasma acidophilum | |
Zn2+ | required | Aeropyrum pernix | |
Zn2+ | required | Sulfurisphaera tokodaii |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dihydroxyacetonephosphate + NAD(P)H | Sulfurisphaera tokodaii | metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | Methanosarcina barkeri | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | Pyrococcus sp. | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | Pyrococcus furiosus | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | Halobacterium salinarum | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | Thermoplasma acidophilum | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | Aeropyrum pernix | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | Methanothermobacter thermautotrophicus | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol-1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | Pyrococcus sp. KS8-1 | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | Thermoplasma acidophilum HO-62 | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | glycerol 1-phosphate + NAD(P)+ | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aeropyrum pernix | - |
- |
- |
Halobacterium salinarum | - |
- |
- |
Methanosarcina barkeri | - |
- |
- |
Methanothermobacter thermautotrophicus | - |
- |
- |
Pyrococcus furiosus | - |
- |
- |
Pyrococcus sp. | - |
- |
- |
Pyrococcus sp. KS8-1 | - |
- |
- |
Sulfurisphaera tokodaii | - |
- |
- |
Thermoplasma acidophilum | - |
- |
- |
Thermoplasma acidophilum HO-62 | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Methanosarcina barkeri | |
sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Pyrococcus sp. | |
sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Methanothermobacter thermautotrophicus | |
sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Pyrococcus furiosus | |
sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Halobacterium salinarum | |
sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Thermoplasma acidophilum | |
sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Aeropyrum pernix | |
sn-glycerol 1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+ | reaction mechanism with transfer of pro-R hydrogen of NAD(P)H and a chiral product | Sulfurisphaera tokodaii |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dihydroxyacetonephosphate + NAD(P)H | metabolic pathway possibilities, overview | Sulfurisphaera tokodaii | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Methanosarcina barkeri | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Pyrococcus sp. | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Pyrococcus furiosus | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Halobacterium salinarum | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Thermoplasma acidophilum | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Aeropyrum pernix | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Methanosarcina barkeri | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Pyrococcus sp. | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Pyrococcus furiosus | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Halobacterium salinarum | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Thermoplasma acidophilum | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Sulfurisphaera tokodaii | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, the reduction reaction is preferred, overview | Aeropyrum pernix | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Pyrococcus sp. KS8-1 | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Pyrococcus sp. KS8-1 | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Thermoplasma acidophilum HO-62 | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Thermoplasma acidophilum HO-62 | glycerol 1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | the enzyme is involved in formation of the enantiomeric glycerophosphate backbone structure of archaeal phospholipids, metabolic pathway possibilities, overview | Methanothermobacter thermautotrophicus | glycerol-1-phosphate + NAD(P)+ | - |
r | |
dihydroxyacetonephosphate + NAD(P)H | active site structure and molecular mechanism, overview | Methanothermobacter thermautotrophicus | glycerol-1-phosphate + NAD(P)+ | - |
r |
Synonyms | Comment | Organism |
---|---|---|
G-1-P dehydrogenase | - |
Methanosarcina barkeri |
G-1-P dehydrogenase | - |
Pyrococcus sp. |
G-1-P dehydrogenase | - |
Methanothermobacter thermautotrophicus |
G-1-P dehydrogenase | - |
Pyrococcus furiosus |
G-1-P dehydrogenase | - |
Halobacterium salinarum |
G-1-P dehydrogenase | - |
Thermoplasma acidophilum |
G-1-P dehydrogenase | - |
Aeropyrum pernix |
G-1-P dehydrogenase | - |
Sulfurisphaera tokodaii |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | preferred cofactor | Methanosarcina barkeri | |
NADH | preferred cofactor | Pyrococcus sp. | |
NADH | preferred cofactor | Methanothermobacter thermautotrophicus | |
NADH | preferred cofactor | Pyrococcus furiosus | |
NADH | preferred cofactor | Halobacterium salinarum | |
NADH | preferred cofactor | Thermoplasma acidophilum | |
NADH | preferred cofactor | Aeropyrum pernix | |
NADH | preferred cofactor | Sulfurisphaera tokodaii | |
NADPH | less active than NADH | Methanosarcina barkeri | |
NADPH | less active than NADH | Pyrococcus sp. | |
NADPH | less active than NADH | Methanothermobacter thermautotrophicus | |
NADPH | less active than NADH | Pyrococcus furiosus | |
NADPH | less active than NADH | Halobacterium salinarum | |
NADPH | less active than NADH | Thermoplasma acidophilum | |
NADPH | less active than NADH | Aeropyrum pernix | |
NADPH | less active than NADH | Sulfurisphaera tokodaii |