Application | Comment | Organism |
---|---|---|
diagnostics | enzyme glyoxylate reductase/hydroxypyruvate reductase is a prognostic marker for hepatocellular carcinoma patients after curative resection. Patients with negative GRHPR both in tumor tissues and nontumoral tissues have a significantly shorter survival time than those with positive GRHPR. Multivariate analysis establishes that GRHPR is detected in nontumoral tissues as an independent prognostic factor for patients with hepatocellular carcinoma, overview | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9UBQ7 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEP-3B cell | - |
Homo sapiens | - |
Hep-G2 cell | - |
Homo sapiens | - |
hepatocellular carcinoma cell | enzyme GRHPR is lost in hepatocellular carcinoma (HCC) and proliferative HCC cells | Homo sapiens | - |
HL-7702 cell | - |
Homo sapiens | - |
Huh-7 cell | GRHPR is reduced in proliferative Huh7 cells | Homo sapiens | - |
additional information | immunohistochemic tissue expression analysis of GRHPR, overview. GRHPR shows a lower expression in tumor tissues than in nontumoral tissues. GRHPR is negatively correlated with Ki-67 | Homo sapiens | - |
SMMC-7721 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
glyoxylate reductase/hydroxypyruvate reductase | - |
Homo sapiens |
GRHPR | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | enzyme deficiency causes primary hyperoxaluria type 2 | Homo sapiens |
metabolism | glyoxylate reductase/hydroxypyruvate reductase (GRHPR) is a key enzyme in the glyoxylate cycle | Homo sapiens |