BRENDA - Enzyme Database show
show all sequences of 1.1.1.247

Enhancement of alkaloid production in opium and California poppy by transactivation using heterologous regulatory factors

Apuya, N.R.; Park, J.H.; Zhang, L.; Ahyow, M.; Davidow, P.; Van Fleet, J.; Rarang, J.C.; Hippley, M.; Johnson, T.W.; Yoo, H.D.; Trieu, A.; Krueger, S.; Wu, C.Y.; Lu, Y.P.; Flavell, R.B.; Bobzin, S.C.; Plant Biotechnol. J. 6, 160-175 (2008)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
additional information
10-100fold increase in enzyme activity of enzymes involved in the biosynthesis of morphinan alkaloids by overexpression of regulatory transcription factors, overview
Eschscholzia californica
additional information
10-100fold increase in enzyme activity of enzymes involved in the biosynthesis of morphinan alkaloids by overexpression of regulatory transcription factors, overview
Papaver somniferum
Cloned(Commentary)
Commentary
Organism
factors involved in transcriptional regulation, overview
Eschscholzia californica
factors involved in transcriptional regulation, overview
Papaver somniferum
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
additional information
Papaver somniferum
the enzyme is involved in biosynthesis of morphinan alkaloids, overview
?
-
-
-
additional information
Eschscholzia californica
the enzyme is involved in biosynthesis of morphinan alkaloids, transcriptional regulation, overview
?
-
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Eschscholzia californica
-
-
-
Papaver somniferum
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
the enzyme is involved in biosynthesis of morphinan alkaloids, overview
689454
Papaver somniferum
?
-
-
-
-
additional information
the enzyme is involved in biosynthesis of morphinan alkaloids, transcriptional regulation, overview
689454
Eschscholzia californica
?
-
-
-
-
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
additional information
10-100fold increase in enzyme activity of enzymes involved in the biosynthesis of morphinan alkaloids by overexpression of regulatory transcription factors, overview
Eschscholzia californica
additional information
10-100fold increase in enzyme activity of enzymes involved in the biosynthesis of morphinan alkaloids by overexpression of regulatory transcription factors, overview
Papaver somniferum
Cloned(Commentary) (protein specific)
Commentary
Organism
factors involved in transcriptional regulation, overview
Eschscholzia californica
factors involved in transcriptional regulation, overview
Papaver somniferum
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
additional information
Papaver somniferum
the enzyme is involved in biosynthesis of morphinan alkaloids, overview
?
-
-
-
additional information
Eschscholzia californica
the enzyme is involved in biosynthesis of morphinan alkaloids, transcriptional regulation, overview
?
-
-
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
the enzyme is involved in biosynthesis of morphinan alkaloids, overview
689454
Papaver somniferum
?
-
-
-
-
additional information
the enzyme is involved in biosynthesis of morphinan alkaloids, transcriptional regulation, overview
689454
Eschscholzia californica
?
-
-
-
-
Other publictions for EC 1.1.1.247
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
724646
Sharafi
Metabolic engineering of morph ...
Papaver somniferum
Biotechnol. Lett.
35
445-453
2013
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1
1
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1
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1
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689454
Apuya
Enhancement of alkaloid produc ...
Eschscholzia californica, Papaver somniferum
Plant Biotechnol. J.
6
160-175
2008
2
-
2
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2
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2
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2
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-
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689451
Larkin
Increasing morphinan alkaloid ...
Papaver somniferum
Plant Biotechnol. J.
5
26-37
2007
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1
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670561
Samanani
The role of phloem sieve eleme ...
Papaver somniferum
Plant J.
47
547-563
2006
-
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1
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4
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1
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2
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2
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1
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670562
Ziegler
Comparative transcript and alk ...
Papaver somniferum
Plant J.
48
177-192
2006
-
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5
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2
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1
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660256
Alcantara
Sanguinarine biosynthesis is a ...
Papaver somniferum
Plant Physiol.
138
173-183
2005
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1
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1
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657166
Weid
The roles of latex and the vas ...
Papaver somniferum
Proc. Natl. Acad. Sci. USA
101
13957-13962
2004
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656969
Bird
A tale of three cell types: al ...
Papaver somniferum
Plant Cell
15
2626-2635
2003
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4
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9551
Lenz
Purification and properties of ...
Papaver somniferum
Eur. J. Biochem.
233
132-139
1995
-
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15
2
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1
2
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2
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5
1
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11
1
2
2
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2
2
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15
2
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5
1
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11
1
2
2
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2
2
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9553
Lenz
-
Stereoselective reduction of c ...
Papaver somniferum
Tetrahedron Lett.
36
2449-2452
1995
-
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1
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6
1
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9552
Gollwitzer
-
The transformation of neopinon ...
Papaver somniferum
Tetrahedron Lett.
34
5703-5706
1993
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