BRENDA - Enzyme Database show
show all sequences of 1.1.1.247

Sanguinarine biosynthesis is associated with the endoplasmic reticulum in cultured opium poppy cells after elicitor treatment

Alcantara, J.; Bird, D.A.; Franceschi, V.R.; Facchini, P.J.; Plant Physiol. 138, 173-183 (2005)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
expressed in Escherichia coli
Papaver somniferum
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
-
Papaver somniferum
5829
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Papaver somniferum
Q9SQ70
opium poppy
-
Purification (Commentary)
Commentary
Organism
Ni21-charged HiTrap column chromatography
Papaver somniferum
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Morphinone + NADPH
-
660256
Papaver somniferum
Morphine + NADP+
-
-
-
?
Cofactor
Cofactor
Commentary
Organism
Structure
NADPH
-
Papaver somniferum
Cloned(Commentary) (protein specific)
Commentary
Organism
expressed in Escherichia coli
Papaver somniferum
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADPH
-
Papaver somniferum
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytosol
-
Papaver somniferum
5829
-
Purification (Commentary) (protein specific)
Commentary
Organism
Ni21-charged HiTrap column chromatography
Papaver somniferum
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Morphinone + NADPH
-
660256
Papaver somniferum
Morphine + NADP+
-
-
-
?
Other publictions for EC 1.1.1.247
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
724646
Sharafi
Metabolic engineering of morph ...
Papaver somniferum
Biotechnol. Lett.
35
445-453
2013
-
1
1
-
1
-
-
-
-
-
-
2
-
3
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
1
1
2
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
689454
Apuya
Enhancement of alkaloid produc ...
Eschscholzia californica, Papaver somniferum
Plant Biotechnol. J.
6
160-175
2008
2
-
2
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
-
-
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2
-
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2
-
2
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-
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2
-
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-
-
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-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
689451
Larkin
Increasing morphinan alkaloid ...
Papaver somniferum
Plant Biotechnol. J.
5
26-37
2007
-
-
1
-
-
-
-
-
-
-
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1
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3
-
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1
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1
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2
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-
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-
670561
Samanani
The role of phloem sieve eleme ...
Papaver somniferum
Plant J.
47
547-563
2006
-
-
-
-
-
-
-
-
1
-
-
-
-
4
-
-
1
-
-
2
-
-
2
-
-
-
-
-
-
-
-
1
-
-
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-
-
1
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1
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1
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2
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2
-
-
-
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-
-
-
-
-
-
-
-
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-
-
670562
Ziegler
Comparative transcript and alk ...
Papaver somniferum
Plant J.
48
177-192
2006
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
-
-
-
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-
-
2
-
-
-
-
-
-
-
-
1
-
-
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-
-
-
1
-
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-
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-
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-
2
-
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-
-
-
-
-
-
-
-
-
-
-
-
-
660256
Alcantara
Sanguinarine biosynthesis is a ...
Papaver somniferum
Plant Physiol.
138
173-183
2005
-
-
1
-
-
-
-
-
1
-
-
-
-
3
-
-
1
-
-
-
-
-
1
-
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-
-
-
-
-
-
1
-
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-
1
1
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1
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1
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1
-
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-
-
-
-
-
-
-
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-
-
-
-
657166
Weid
The roles of latex and the vas ...
Papaver somniferum
Proc. Natl. Acad. Sci. USA
101
13957-13962
2004
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
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-
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3
-
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3
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656969
Bird
A tale of three cell types: al ...
Papaver somniferum
Plant Cell
15
2626-2635
2003
-
-
-
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-
-
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1
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4
-
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1
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1
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1
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1
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1
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-
9551
Lenz
Purification and properties of ...
Papaver somniferum
Eur. J. Biochem.
233
132-139
1995
-
-
-
-
-
-
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15
2
-
1
2
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2
-
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1
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5
1
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11
1
2
2
-
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2
2
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2
-
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2
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-
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-
15
2
-
1
2
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1
-
5
1
-
11
1
2
2
-
-
2
2
-
-
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-
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-
-
-
9553
Lenz
-
Stereoselective reduction of c ...
Papaver somniferum
Tetrahedron Lett.
36
2449-2452
1995
-
-
-
-
-
-
-
-
-
-
1
1
-
1
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2
-
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6
1
-
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1
1
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2
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6
1
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9552
Gollwitzer
-
The transformation of neopinon ...
Papaver somniferum
Tetrahedron Lett.
34
5703-5706
1993
-
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1
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1
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