BRENDA - Enzyme Database show
show all sequences of 1.1.1.243

Monoterpene biosynthesis pathway construction in Escherichia coli

Carter, O.A.; Peters, R.J.; Croteau, R.; Phytochemistry 64, 425-433 (2003)

Data extracted from this reference:

Application
Application
Commentary
Organism
nutrition
evaluation of recombinant industrial scale production of (-)-carvone, the spearmint monoterpene ketone, in Escherichia coli for commercial use, overview
Mentha spicata
Cloned(Commentary)
Commentary
Organism
the installation of the (-)-carvone biosynthesis from dimethyl allyl diphosphate of Menta spicata in Escherichia coli is not successful due to secretion of the intermediate (-)-limonene, after feeding of (-)limonen to recombinant bacteria, (-)-carvone is produced
Mentha spicata
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(-)-trans carveol + NADP+
Mentha spicata
last step of (-)-carvone biosynthesis
(-)-carvone + NADPH
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Mentha spicata
-
spearmint
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(-)-trans carveol + NADP+
-
656954
Mentha spicata
(-)-carvone + NADPH
-
-
-
?
(-)-trans carveol + NADP+
last step of (-)-carvone biosynthesis
656954
Mentha spicata
(-)-carvone + NADPH
-
-
-
?
Application (protein specific)
Application
Commentary
Organism
nutrition
evaluation of recombinant industrial scale production of (-)-carvone, the spearmint monoterpene ketone, in Escherichia coli for commercial use, overview
Mentha spicata
Cloned(Commentary) (protein specific)
Commentary
Organism
the installation of the (-)-carvone biosynthesis from dimethyl allyl diphosphate of Menta spicata in Escherichia coli is not successful due to secretion of the intermediate (-)-limonene, after feeding of (-)limonen to recombinant bacteria, (-)-carvone is produced
Mentha spicata
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(-)-trans carveol + NADP+
Mentha spicata
last step of (-)-carvone biosynthesis
(-)-carvone + NADPH
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(-)-trans carveol + NADP+
-
656954
Mentha spicata
(-)-carvone + NADPH
-
-
-
?
(-)-trans carveol + NADP+
last step of (-)-carvone biosynthesis
656954
Mentha spicata
(-)-carvone + NADPH
-
-
-
?
Other publictions for EC 1.1.1.243
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
670589
Ringer
Monoterpene metabolism. Clonin ...
Mentha spicata
Plant Physiol.
137
863-872
2005
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1
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1
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1
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1
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1
1
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1
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-
-
-
-
-
656954
Carter
Monoterpene biosynthesis pathw ...
Mentha spicata
Phytochemistry
64
425-433
2003
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1
1
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286371
Tecelao
-
Development of a reaction syst ...
Rhodococcus erythropolis
J. Mol. Catal. , B Enzym.
11
719-724
2001
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-
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1
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1
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1
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-
656560
Tecelao
-
Development of a reaction syst ...
Rhodococcus erythropolis, Rhodococcus erythropolis DCL14
J. Mol. Catal. B
11
719-724
2001
2
2
-
-
-
-
-
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-
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2
-
7
-
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1
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4
-
1
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1
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-
1
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2
2
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1
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2
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1
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4
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1
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1
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286370
van der Werf
Metabolism of carveol and dihy ...
Rhodococcus erythropolis
Microbiology
146
1129-1141
2000
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1
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1
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9
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2
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2
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9
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286369
van der Werft
Stereoselective carveol dehydr ...
Rhodococcus erythropolis, Rhodococcus erythropolis DCL14
J. Biol. Chem.
274
26296-26304
1999
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-
-
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4
-
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2
2
-
10
-
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1
1
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1
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24
1
1
1
1
-
1
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1
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1
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4
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2
2
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1
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1
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24
1
1
1
1
-
1
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286368
Gershenzon
Biochemical and histochemical ...
Mentha spicata
Plant Physiol.
89
1351-1357
1989
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1
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2
1
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1
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2
1
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2
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1
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1
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1
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1
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1
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1
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2
1
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2
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1
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