BRENDA - Enzyme Database show
show all sequences of 1.1.1.24

Purification and characterization of the quinate: oxidoreductase from Phaseolus mungo sprouts

Kang, X.; Scheibe, R.; Phytochemistry 33, 769-773 (1993)
No PubMed abstract available

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
Aromatic amino acids
slightly increased quinate oxidation
Vigna radiata var. radiata
erythrose 4-phosphate
erythrose 4-phosphate plus phosphoenolpyruvate increase quinate oxidizing activity by 25%
Vigna radiata var. radiata
phosphoenolpyruvate
erythrose 4-phosphate plus phosphoenolpyruvate increase quinate oxidizing activity by 25%
Vigna radiata var. radiata
Inhibitors
Inhibitors
Commentary
Organism
Structure
Aromatic amino acids
inhibit reduction of dehydroquinate
Vigna radiata var. radiata
shikimic acid
competitive inhibition
Vigna radiata var. radiata
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.009
-
NADH
-
Vigna radiata var. radiata
0.047
-
3-dehydroquinate
-
Vigna radiata var. radiata
0.05
-
NAD+
-
Vigna radiata var. radiata
0.12
-
NADPH
-
Vigna radiata var. radiata
0.37
-
quinate
-
Vigna radiata var. radiata
0.45
-
3-dehydroquinate
-
Vigna radiata var. radiata
0.7
-
NADP+
-
Vigna radiata var. radiata
3
-
quinate
-
Vigna radiata var. radiata
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
55000
-
3 * 55000, SDS-PAGE
Vigna radiata var. radiata
160000
-
gel filtration
Vigna radiata var. radiata
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3-dehydroquinate + NADH
Vigna radiata var. radiata
-
quinate + NAD+
-
-
r
quinate + NAD+
Vigna radiata var. radiata
-
5-dehydroquinate + NADH + H+
-
-
r
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Vigna radiata var. radiata
-
-
-
Purification (Commentary)
Commentary
Organism
to homogenity
Vigna radiata var. radiata
Source Tissue
Source Tissue
Commentary
Organism
Textmining
seedling
-
Vigna radiata var. radiata
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
29.99
-
-
Vigna radiata var. radiata
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3-dehydroquinate + NADH
-
286365
Vigna radiata var. radiata
quinate + NAD+
-
-
-
r
quinate + NAD+
-
286365
Vigna radiata var. radiata
5-dehydroquinate + NADH + H+
-
-
-
r
quinic acid + NAD(P)+
-
286365
Vigna radiata var. radiata
dehydroquinic acid + NAD(P)H + H+
-
-
-
-
Subunits
Subunits
Commentary
Organism
trimer
3 * 55000, SDS-PAGE
Vigna radiata var. radiata
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
can also utilize NADP+/NADPH
Vigna radiata var. radiata
NADH
can also utilize NADP+/NADPH
Vigna radiata var. radiata
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
Aromatic amino acids
slightly increased quinate oxidation
Vigna radiata var. radiata
erythrose 4-phosphate
erythrose 4-phosphate plus phosphoenolpyruvate increase quinate oxidizing activity by 25%
Vigna radiata var. radiata
phosphoenolpyruvate
erythrose 4-phosphate plus phosphoenolpyruvate increase quinate oxidizing activity by 25%
Vigna radiata var. radiata
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
can also utilize NADP+/NADPH
Vigna radiata var. radiata
NADH
can also utilize NADP+/NADPH
Vigna radiata var. radiata
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
Aromatic amino acids
inhibit reduction of dehydroquinate
Vigna radiata var. radiata
shikimic acid
competitive inhibition
Vigna radiata var. radiata
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.009
-
NADH
-
Vigna radiata var. radiata
0.047
-
3-dehydroquinate
-
Vigna radiata var. radiata
0.05
-
NAD+
-
Vigna radiata var. radiata
0.12
-
NADPH
-
Vigna radiata var. radiata
0.37
-
quinate
-
Vigna radiata var. radiata
0.45
-
3-dehydroquinate
-
Vigna radiata var. radiata
0.7
-
NADP+
-
Vigna radiata var. radiata
3
-
quinate
-
Vigna radiata var. radiata
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
55000
-
3 * 55000, SDS-PAGE
Vigna radiata var. radiata
160000
-
gel filtration
Vigna radiata var. radiata
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3-dehydroquinate + NADH
Vigna radiata var. radiata
-
quinate + NAD+
-
-
r
quinate + NAD+
Vigna radiata var. radiata
-
5-dehydroquinate + NADH + H+
-
-
r
Purification (Commentary) (protein specific)
Commentary
Organism
to homogenity
Vigna radiata var. radiata
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
seedling
-
Vigna radiata var. radiata
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
29.99
-
-
Vigna radiata var. radiata
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3-dehydroquinate + NADH
-
286365
Vigna radiata var. radiata
quinate + NAD+
-
-
-
r
quinate + NAD+
-
286365
Vigna radiata var. radiata
5-dehydroquinate + NADH + H+
-
-
-
r
quinic acid + NAD(P)+
-
286365
Vigna radiata var. radiata
dehydroquinic acid + NAD(P)H + H+
-
-
-
-
Subunits (protein specific)
Subunits
Commentary
Organism
trimer
3 * 55000, SDS-PAGE
Vigna radiata var. radiata
Other publictions for EC 1.1.1.24
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
727115
Höppner
Enzyme-substrate complexes of ...
Corynebacterium glutamicum, Corynebacterium glutamicum ATCC 13032
Biol. Chem.
394
1505-1516
2013
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1
1
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8
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1
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6
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1
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8
2
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1
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8
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1
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6
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1
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8
2
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8
8
698068
Marsh
Changes in quinic acid metabol ...
Actinidia arguta, Actinidia arguta var. arguta, Actinidia chinensis, Actinidia deliciosa, Actinidia deliciosa var. deliciosa
Funct. Plant Biol.
36
463-470
2009
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5
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3
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5
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1
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5
3
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3
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3
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6
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6
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5
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3
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1
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5
3
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3
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3
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684153
Schoepe
1.6 A structure of an NAD(+)-d ...
Corynebacterium glutamicum
Acta Crystallogr. Sect. D
64
803-809
2008
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4
1
1
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2
2
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657345
Shein
-
The content of phenolic compou ...
Pinus sylvestris
Russ. J. Plant Physiol.
50
516-521
2003
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1
1
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286364
Ossipov
-
Broad-specificity quinate (shi ...
Daucus carota, Pinus taeda
Plant Physiol.
38
923-928
2000
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4
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2
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1
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3
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286363
Grund
Utilization of quinate and p-h ...
Pseudonocardia sp., Rhodococcus rhodochrous, Streptomyces sp.
J. Basic Microbiol.
38
241-255
1998
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5
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3
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6
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286362
Kang
-
Subcellular localization of qu ...
Vigna radiata var. radiata
Z. Naturforsch. C
49
415-420
1994
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5487
Hawkins
Characterization of the 3-dehy ...
Aspergillus nidulans
Biochem. J.
296
451-457
1993
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286365
Kang
-
Purification and characterizat ...
Vigna radiata var. radiata
Phytochemistry
33
769-773
1993
3
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2
8
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2
2
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1
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286359
Graziana
-
The reversible association of ...
Daucus carota
FEBS Lett.
163
306-311
1983
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286356
Barea
Purification and characterizat ...
Neurospora crassa
Biochim. Biophys. Acta
524
1-14
1978
1
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286357
Cain
The identity of shikimate dehy ...
Aspergillus niger
Biochem. J.
127
15P
1972
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6
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684945
Cain
Metabolism of shikimate and qu ...
Aspergillus niger
Biochem. J.
127
15P-16P
1972
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286358
Gamborg
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Aromatic metabolism in plants ...
Vigna radiata var. radiata
Biochim. Biophys. Acta
128
483-491
1966
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286360
Davies
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Enzymes of aromatic biosynthes ...
Enterobacter aerogenes
Methods Enzymol.
2
307-311
1955
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