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Literature summary for 1.1.1.24 extracted from

  • Kang, X.; Scheibe, R.
    Purification and characterization of the quinate: oxidoreductase from Phaseolus mungo sprouts (1993), Phytochemistry, 33, 769-773.
No PubMed abstract available
Search for more literature for 1.1.1.24

Activating Compound

Activating Compound Comment Organism Structure
Aromatic amino acids slightly increased quinate oxidation Vigna radiata var. radiata
erythrose 4-phosphate erythrose 4-phosphate plus phosphoenolpyruvate increase quinate oxidizing activity by 25% Vigna radiata var. radiata
phosphoenolpyruvate erythrose 4-phosphate plus phosphoenolpyruvate increase quinate oxidizing activity by 25% Vigna radiata var. radiata

Inhibitors

Inhibitors Comment Organism Structure
Aromatic amino acids inhibit reduction of dehydroquinate Vigna radiata var. radiata
shikimic acid competitive inhibition Vigna radiata var. radiata

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.009
-
 NADH
-
 Vigna radiata var. radiata
0.047
-
 3-dehydroquinate
-
 Vigna radiata var. radiata
0.05
-
 NAD+
-
 Vigna radiata var. radiata
0.12
-
 NADPH
-
 Vigna radiata var. radiata
0.37
-
 quinate
-
 Vigna radiata var. radiata
0.45
-
 3-dehydroquinate
-
 Vigna radiata var. radiata
0.7
-
 NADP+
-
 Vigna radiata var. radiata
3
-
 quinate
-
 Vigna radiata var. radiata

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
 3 * 55000, SDS-PAGE Vigna radiata var. radiata
160000
-
 gel filtration Vigna radiata var. radiata

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-dehydroquinate + NADH Vigna radiata var. radiata
-
 quinate + NAD+
-
 r
quinate + NAD+ Vigna radiata var. radiata
-
 5-dehydroquinate + NADH + H+
-
 r

Organism

Organism UniProt Comment Textmining
Vigna radiata var. radiata
-
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogenity Vigna radiata var. radiata

Source Tissue

Source Tissue Comment Organism Textmining
seedling
-
 Vigna radiata var. radiata
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
29.99
-
-
 Vigna radiata var. radiata

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-dehydroquinate + NADH
-
 Vigna radiata var. radiata quinate + NAD+
-
 r
quinate + NAD+
-
 Vigna radiata var. radiata 5-dehydroquinate + NADH + H+
-
 r
quinic acid + NAD(P)+
-
 Vigna radiata var. radiata dehydroquinic acid + NAD(P)H + H+
-
 ?

Subunits

Subunits Comment Organism
trimer 3 * 55000, SDS-PAGE Vigna radiata var. radiata

Cofactor

Cofactor Comment Organism Structure
NAD+ can also utilize NADP+/NADPH Vigna radiata var. radiata
NADH can also utilize NADP+/NADPH Vigna radiata var. radiata