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Literature summary for 1.1.1.237 extracted from

  • Lu, X.; Hao, L.; Wang, F.; Huang, C.
    Molecular cloning, characterization and expression analysis of a gene encoding hydroxyphenylpyruvate reductase involved in rosmarinic acid biosynthesis pathway from Perilla frutescens (2014), Proc. 2012 Int. Conf. Appl. Biotechnol., 251 LNEE, 1807-1820.
No PubMed abstract available

Cloned(Commentary)

Cloned (Comment) Organism
gene PfHPPR, DNA and amino acid sequence determination and analysis, sequence comparisons, quantitative real-time PCR enzyme expression analysis Perilla frutescens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
34422
-
-
Perilla frutescens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-(4-hydroxyphenyl)pyruvate + NADH + H+ Perilla frutescens
-
3-(4-hydroxyphenyl)lactate + NAD+
-
r

Organism

Organism UniProt Comment Textmining
Perilla frutescens F8RGR8
-
-

Source Tissue

Source Tissue Comment Organism Textmining
leaf
-
Perilla frutescens
-
additional information quantitative real-time PCR analysis of the transcription pattern indicates that the PfHPPR expresses constitutively in all examined tissues but most highly in leaves Perilla frutescens
-
root
-
Perilla frutescens
-
stem
-
Perilla frutescens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-(4-hydroxyphenyl)pyruvate + NADH + H+
-
Perilla frutescens 3-(4-hydroxyphenyl)lactate + NAD+
-
r

Subunits

Subunits Comment Organism
? x * 34422, sequence calculation Perilla frutescens
More secondary structure, and homology-based structural modeling Perilla frutescens

Synonyms

Synonyms Comment Organism
HPPR
-
Perilla frutescens

Cofactor

Cofactor Comment Organism Structure
NADH
-
Perilla frutescens

pI Value

Organism Comment pI Value Maximum pI Value
Perilla frutescens sequence calculation
-
5.58

Expression

Organism Comment Expression
Perilla frutescens expression of PfHPPR can be induced by several factors such as abscisic acid (ABA), salicylic acid (SA), and ultraviolet-B radiation (UV-B) up

General Information

General Information Comment Organism
evolution comparison of HPPR gene sequences from Perilla frutescens and other species reveals that the HPPR genes are structurally conserved and might possess similar functions Perilla frutescens
metabolism hydroxyphenylpyruvate reductase is involved in rosmarinic acid biosynthesis via the tyrosine pathway Perilla frutescens
additional information homology-based structural modeling Perilla frutescens