BRENDA - Enzyme Database show
show all sequences of 1.1.1.237

Influence of growth regulators and sucrose concentrations on growth and rosmarinic acid production in calli and suspension cultures of Coleus blumei

Qian, J.; Guiping, L.; Xiujun, L.; Xincai, H.; Hongmei, L.; Nat. Prod. Res. 23, 127-137 (2009)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
additional information
best result for rosmarinic acid accumulation is obtained when B5-medium supplemented is with 2.0 mg/l 6-benzyl-aminopurine, 0.5 mg/l alpha-naphthaleneacetic, 0.8 mg/L 2,4-dichlorophenxyaretic acid and 2% sucrose, and solidified with 0.8% agar. Both growth index and rosmarinic acid accumulation reach a maximum, which is 49.7 and 25.3% (dry weight), respectively. Rosmarinic acid accumulation is enhanced by the sucrose concentrations
Solenostemon scutellarioides
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Solenostemon scutellarioides
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
callus
-
Solenostemon scutellarioides
-
leaf
-
Solenostemon scutellarioides
-
root
-
Solenostemon scutellarioides
-
stem
-
Solenostemon scutellarioides
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
rosmarinic acid biosynthetic pathway is regulated by interactions of several enzymes necessary for biosynthesis including HPPR
700368
Solenostemon scutellarioides
?
-
-
-
-
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
additional information
best result for rosmarinic acid accumulation is obtained when B5-medium supplemented is with 2.0 mg/l 6-benzyl-aminopurine, 0.5 mg/l alpha-naphthaleneacetic, 0.8 mg/L 2,4-dichlorophenxyaretic acid and 2% sucrose, and solidified with 0.8% agar. Both growth index and rosmarinic acid accumulation reach a maximum, which is 49.7 and 25.3% (dry weight), respectively. Rosmarinic acid accumulation is enhanced by the sucrose concentrations
Solenostemon scutellarioides
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
callus
-
Solenostemon scutellarioides
-
leaf
-
Solenostemon scutellarioides
-
root
-
Solenostemon scutellarioides
-
stem
-
Solenostemon scutellarioides
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
additional information
rosmarinic acid biosynthetic pathway is regulated by interactions of several enzymes necessary for biosynthesis including HPPR
700368
Solenostemon scutellarioides
?
-
-
-
-
Other publictions for EC 1.1.1.237
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
741036
Battini
Rhizophagus intraradices or it ...
Ocimum basilicum var. purpurascens
Mycorrhiza
26
699-707
2016
-
-
1
-
-
-
-
-
-
-
-
1
-
10
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
2
1
1
2
-
-
739156
Kim
Molecular cloning and characte ...
Scutellaria baicalensis
Nat. Prod. Commun.
9
1311-1314
2014
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
741057
Dewanjee
Enhanced rosmarinic acid biosy ...
Solenostemon scutellarioides
Nat. Prod. Res.
28
1691-1698
2014
1
-
-
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
741318
Lu
-
Molecular cloning, characteriz ...
Perilla frutescens
Proc. 2012 Int. Conf. Appl. Biotechnol.
251 LNEE
1807-1820
2014
-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
4
-
-
1
2
-
-
-
-
-
-
-
1
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
4
-
-
1
2
-
-
-
-
-
-
-
1
1
3
3
1
-
-
739871
Ma
Regulation of water-soluble ph ...
Salvia miltiorrhiza
Appl. Biochem. Biotechnol.
170
1253-1262
2013
-
-
1
-
1
-
-
-
-
-
-
1
-
4
-
-
-
-
-
5
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
5
-
-
1
-
-
-
-
-
-
-
-
-
2
2
2
2
-
-
741143
Huecherig
-
RNAi suppression and overexpre ...
Solenostemon scutellarioides
Plant Cell Tissue Organ. Cult.
113
375-385
2013
-
-
1
-
1
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
1
-
-
-
-
-
-
-
-
-
2
2
-
-
-
741144
Barberini
-
Molecular cloning of SoHPPR en ...
Salvia officinalis
Plant Cell Tissue Organ. Cult.
114
131-138
2013
-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
-
-
-
-
1
1
-
-
-
724428
Fujii
Novel fungal phenylpyruvate re ...
Wickerhamia fluorescens, Wickerhamia fluorescens TK1
Biochim. Biophys. Acta
1814
1669-1676
2011
-
-
1
-
-
-
5
6
-
-
3
-
-
2
-
-
-
-
-
-
1
-
10
1
-
-
-
6
1
-
-
4
-
-
-
-
-
1
4
-
-
-
-
5
-
6
-
-
3
-
-
-
-
-
-
-
1
-
10
1
-
-
-
6
1
-
-
-
1
1
1
1
6
6
723825
Janiak
Structure and substrate dockin ...
Solenostemon scutellarioides
Acta Crystallogr. Sect. D
66
593-603
2010
-
-
1
1
-
-
-
-
-
-
1
1
-
3
-
-
1
-
-
1
-
-
5
2
-
-
-
-
-
-
-
3
-
-
-
-
-
1
3
1
-
-
-
-
-
-
-
-
1
1
-
-
-
1
-
1
-
-
5
2
-
-
-
-
-
-
-
-
-
2
2
-
-
-
700368
Qian
Influence of growth regulators ...
Solenostemon scutellarioides
Nat. Prod. Res.
23
127-137
2009
1
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
700648
Xiao
Methyl jasmonate dramatically ...
Salvia miltiorrhiza
Physiol. Plant.
137
1-9
2009
1
-
-
-
-
-
-
-
-
-
-
1
-
2
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
657023
Kim
Purification, cloning and func ...
Solenostemon scutellarioides
Plant Mol. Biol.
54
311-323
2004
-
-
1
-
-
-
-
-
1
-
3
1
-
5
-
-
1
-
-
1
1
-
3
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
3
1
-
-
-
1
-
1
1
-
3
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286351
Petersen
-
The biosynthesis of rosmarinic ...
Solenostemon scutellarioides
Plant Cell Tissue Organ Cult.
38
171 - 179
1994
-
-
-
-
-
-
4
4
-
-
-
1
-
1
-
-
1
-
-
-
-
-
3
-
-
-
-
-
1
-
-
2
-
-
-
-
-
-
2
-
-
-
-
4
-
4
-
-
-
1
-
-
-
1
-
-
-
-
3
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
286352
Petersen
-
Proposed biosynthetic pathway ...
Solenostemon scutellarioides
Planta
189
10-14
1993
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286350
Häusler
-
Hydroxyphenylpyruvate reductas ...
Solenostemon scutellarioides
Z. Naturforsch. C
46
371-376
1991
-
-
-
-
-
-
5
5
-
-
-
1
-
1
-
-
-
-
-
-
-
2
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
5
-
-
-
1
-
-
-
-
-
-
-
2
4
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
286349
Petersen
-
Two new enzymes of rosmarinic ...
Solenostemon scutellarioides
Z. Naturforsch. C
43
501-504
1988
2
-
-
-
-
1
-
-
-
-
-
1
-
1
-
-
1
-
-
-
-
-
3
-
-
-
-
-
-
-
-
2
-
-
-
2
-
-
2
-
-
1
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-