BRENDA - Enzyme Database show
show all sequences of 1.1.1.237

The biosynthesis of rosmarinic acid in suspension cultures of Coleus blumei

Petersen, M.; Häusler E.; Meinhard J.; Karwatzki, B.; Gertlowski C.; Plant Cell Tissue Organ Cult. 38, 171 - 179 (1994)
No PubMed abstract available

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
oxaloacetate
inhibition at 5 mM
Solenostemon scutellarioides
p-Coumaroyl-CoA
-
Solenostemon scutellarioides
pyruvate
inhibition at 4 mM
Solenostemon scutellarioides
rosmarinic acid
-
Solenostemon scutellarioides
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
10
-
4-hydroxyphenylpyruvate
-
Solenostemon scutellarioides
95
-
NADPH
-
Solenostemon scutellarioides
130
-
3,4-Dihydroxyphenylpyruvate
-
Solenostemon scutellarioides
190
-
NADH
-
Solenostemon scutellarioides
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3-(4-hydroxyphenyl)lactate + NAD+
Solenostemon scutellarioides
-
4-hydroxyphenylpyruvate + NADH
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Solenostemon scutellarioides
-
-
-
Purification (Commentary)
Commentary
Organism
-
Solenostemon scutellarioides
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3,4-dihydroxyphenylpyruvate + NADH
-
286351
Solenostemon scutellarioides
3-(3,4-dihydroxyphenyl)lactate + NAD+
-
286351
Solenostemon scutellarioides
r
3-(4-hydroxyphenyl)lactate + NAD+
-
286351
Solenostemon scutellarioides
4-hydroxyphenylpyruvate + NADH
-
-
-
?
4-hydroxyphenylpyruvate + NADH
-
286351
Solenostemon scutellarioides
3-(4-hydroxyphenyl)lactate + NAD+
-
286351
Solenostemon scutellarioides
r
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.5
7
-
Solenostemon scutellarioides
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Solenostemon scutellarioides
NADP+
-
Solenostemon scutellarioides
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Solenostemon scutellarioides
NADP+
-
Solenostemon scutellarioides
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
oxaloacetate
inhibition at 5 mM
Solenostemon scutellarioides
p-Coumaroyl-CoA
-
Solenostemon scutellarioides
pyruvate
inhibition at 4 mM
Solenostemon scutellarioides
rosmarinic acid
-
Solenostemon scutellarioides
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
10
-
4-hydroxyphenylpyruvate
-
Solenostemon scutellarioides
95
-
NADPH
-
Solenostemon scutellarioides
130
-
3,4-Dihydroxyphenylpyruvate
-
Solenostemon scutellarioides
190
-
NADH
-
Solenostemon scutellarioides
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3-(4-hydroxyphenyl)lactate + NAD+
Solenostemon scutellarioides
-
4-hydroxyphenylpyruvate + NADH
-
-
?
Purification (Commentary) (protein specific)
Commentary
Organism
-
Solenostemon scutellarioides
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3,4-dihydroxyphenylpyruvate + NADH
-
286351
Solenostemon scutellarioides
3-(3,4-dihydroxyphenyl)lactate + NAD+
-
286351
Solenostemon scutellarioides
r
3-(4-hydroxyphenyl)lactate + NAD+
-
286351
Solenostemon scutellarioides
4-hydroxyphenylpyruvate + NADH
-
-
-
?
4-hydroxyphenylpyruvate + NADH
-
286351
Solenostemon scutellarioides
3-(4-hydroxyphenyl)lactate + NAD+
-
286351
Solenostemon scutellarioides
r
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.5
7
-
Solenostemon scutellarioides
Other publictions for EC 1.1.1.237
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
724428
Fujii
Novel fungal phenylpyruvate re ...
Wickerhamia fluorescens, Wickerhamia fluorescens TK1
Biochim. Biophys. Acta
1814
1669-1676
2011
-
-
1
-
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5
6
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-
3
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2
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1
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10
1
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6
1
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4
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1
4
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5
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6
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3
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-
1
-
10
1
-
-
-
6
1
-
-
-
1
1
1
1
6
6
723825
Janiak
Structure and substrate dockin ...
Solenostemon scutellarioides
Acta Crystallogr. Sect. D
66
593-603
2010
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-
1
1
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1
1
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3
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1
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1
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5
2
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1
3
1
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1
1
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1
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1
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5
2
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2
2
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700368
Qian
Influence of growth regulators ...
Solenostemon scutellarioides
Nat. Prod. Res.
23
127-137
2009
1
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4
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1
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700648
Xiao
Methyl jasmonate dramatically ...
Salvia miltiorrhiza
Physiol. Plant.
137
1-9
2009
1
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1
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2
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657023
Kim
Purification, cloning and func ...
Solenostemon scutellarioides
Plant Mol. Biol.
54
311-323
2004
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1
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1
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3
1
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5
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1
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1
1
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3
1
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1
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1
1
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1
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1
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1
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1
1
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3
1
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286351
Petersen
-
The biosynthesis of rosmarinic ...
Solenostemon scutellarioides
Plant Cell Tissue Organ Cult.
38
171 - 179
1994
-
-
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-
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4
4
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1
-
1
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1
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3
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1
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2
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2
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4
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4
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1
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1
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3
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1
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286352
Petersen
-
Proposed biosynthetic pathway ...
Solenostemon scutellarioides
Planta
189
10-14
1993
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1
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1
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286350
Häusler
-
Hydroxyphenylpyruvate reductas ...
Solenostemon scutellarioides
Z. Naturforsch. C
46
371-376
1991
-
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5
5
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1
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1
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2
4
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1
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1
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5
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5
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1
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2
4
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1
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1
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-
286349
Petersen
-
Two new enzymes of rosmarinic ...
Solenostemon scutellarioides
Z. Naturforsch. C
43
501-504
1988
2
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1
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1
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1
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2
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2
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1
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1
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1
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3
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