KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0083 | - |
(15S)-15-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid | - |
Mus musculus | |
0.06 | - |
NAD+ | - |
Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | tightly bound to membranes | Mus musculus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
Storage Stability | Organism |
---|---|
4°C enzyme in microsomal fraction very stable, cytosolic and mitochondrial fractions more than 90% loss of activity within 1 day | Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(15S)-15-hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + NAD(P)+ | - |
Mus musculus | 15-oxo-5,8,11-cis-13-trans-eicosatetraenoate + NAD(P)H | - |
? | |
15(S)-15-hydroxy-5,8,11-cis-13-trans-icosatetranoate + NAD+ | - |
Mus musculus | 15-oxo-5,8,11-cis-13-trans-icosatetraenoate + NADH + H+ | - |
r |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9.8 | - |
- |
Mus musculus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
7.6 | 11.2 | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | almost the same reaction rates with NAD+ and NADP+ | Mus musculus | |
NADP+ | almost the same reaction rates with NAD+ and NADP+ | Mus musculus |