BRENDA - Enzyme Database show
show all sequences of 1.1.1.232

15-Hydroxyeicosatetraenoic acid dehydrogenase activity in microsomal fraction of mouse liver homogenate

Sok, D.E.; Kang, J.B.; Shin, H.D.; Biochem. Biophys. Res. Commun. 156, 524-529 (1988)

Data extracted from this reference:

KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.0083
-
(15S)-15-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid
-
Mus musculus
0.06
-
NAD+
-
Mus musculus
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
tightly bound to membranes
Mus musculus
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Mus musculus
-
-
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
liver
-
Mus musculus
-
Storage Stability
Storage Stability
Organism
4C enzyme in microsomal fraction very stable, cytosolic and mitochondrial fractions more than 90% loss of activity within 1 day
Mus musculus
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(15S)-15-hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + NAD(P)+
-
286345
Mus musculus
15-oxo-5,8,11-cis-13-trans-eicosatetraenoate + NAD(P)H
-
-
-
-
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
9.8
-
-
Mus musculus
pH Range
pH Minimum
pH Maximum
Commentary
Organism
7.6
11.2
-
Mus musculus
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
almost the same reaction rates with NAD+ and NADP+
Mus musculus
NADP+
almost the same reaction rates with NAD+ and NADP+
Mus musculus
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
almost the same reaction rates with NAD+ and NADP+
Mus musculus
NADP+
almost the same reaction rates with NAD+ and NADP+
Mus musculus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.0083
-
(15S)-15-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid
-
Mus musculus
0.06
-
NAD+
-
Mus musculus
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
microsome
tightly bound to membranes
Mus musculus
-
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
liver
-
Mus musculus
-
Storage Stability (protein specific)
Storage Stability
Organism
4C enzyme in microsomal fraction very stable, cytosolic and mitochondrial fractions more than 90% loss of activity within 1 day
Mus musculus
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(15S)-15-hydroxy-5,8,11-cis-13-trans-eicosatetraenoate + NAD(P)+
-
286345
Mus musculus
15-oxo-5,8,11-cis-13-trans-eicosatetraenoate + NAD(P)H
-
-
-
-
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
9.8
-
-
Mus musculus
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
7.6
11.2
-
Mus musculus
Other publictions for EC 1.1.1.232
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
286345
Sok
15-Hydroxyeicosatetraenoic aci ...
Mus musculus
Biochem. Biophys. Res. Commun.
156
524-529
1988
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