BRENDA - Enzyme Database show
show all sequences of 1.1.1.231

Expression of NADP(+)-Dependent 15-Hydroxyprostaglandin Dehydrogenase mRNA in Monkey Ocular Tissues and Characterization of Its Recombinant Enzyme

Fujimori, K.; Okada, T.; Urade, Y.; J. Biochem. 131, 383-389 (2002)

Data extracted from this reference:

Cloned(Commentary)
Commentary
Organism
-
Macaca fascicularis
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
31000
-
SDs-PAGE of recombinant enzyme
Macaca fascicularis
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Macaca fascicularis
-
monkey
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
eye
-
Macaca fascicularis
-
additional information
tissue distribution of m-RNA
Macaca fascicularis
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
1.217
-
recombinant enzyme, latanoprost + NADP+
Macaca fascicularis
2.17
-
recombinant enzyme, acid form of latanoprost + NADP+
Macaca fascicularis
6.08
-
recombinant enzyme, prostaglandin F2alpha + NAD+
Macaca fascicularis
9.8
-
recombinant enzyme, prostaglandin E2 + NADP+
Macaca fascicularis
24.3
-
recombinant enzyme, prostaglandin F2alpha + NADP+
Macaca fascicularis
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
prostaglandin E2 + NADP+
-
348015
Macaca fascicularis
15-ketoprostaglandin E2 + NADPH + H+
-
-
-
?
prostaglandin F2alpha + NAD+
-
348015
Macaca fascicularis
15-ketoprostaglandin F2alpha + NADH + H+
-
-
-
?
prostaglandin F2alpha + NADP+
-
348015
Macaca fascicularis
15-ketoprostaglandin F2alpha + NADPH + H+
-
-
-
?
Cloned(Commentary) (protein specific)
Commentary
Organism
-
Macaca fascicularis
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
31000
-
SDs-PAGE of recombinant enzyme
Macaca fascicularis
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
eye
-
Macaca fascicularis
-
additional information
tissue distribution of m-RNA
Macaca fascicularis
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
1.217
-
recombinant enzyme, latanoprost + NADP+
Macaca fascicularis
2.17
-
recombinant enzyme, acid form of latanoprost + NADP+
Macaca fascicularis
6.08
-
recombinant enzyme, prostaglandin F2alpha + NAD+
Macaca fascicularis
9.8
-
recombinant enzyme, prostaglandin E2 + NADP+
Macaca fascicularis
24.3
-
recombinant enzyme, prostaglandin F2alpha + NADP+
Macaca fascicularis
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
prostaglandin E2 + NADP+
-
348015
Macaca fascicularis
15-ketoprostaglandin E2 + NADPH + H+
-
-
-
?
prostaglandin F2alpha + NAD+
-
348015
Macaca fascicularis
15-ketoprostaglandin F2alpha + NADH + H+
-
-
-
?
prostaglandin F2alpha + NADP+
-
348015
Macaca fascicularis
15-ketoprostaglandin F2alpha + NADPH + H+
-
-
-
?
Other publictions for EC 1.1.1.231
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
348015
Fujimori
Expression of NADP(+)-Dependen ...
Macaca fascicularis
J. Biochem.
131
383-389
2002
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1
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2
5
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3
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1
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2
5
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3
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348016
Terada
Characterization of multiple C ...
Cricetulus griseus
Chem. Biol. Interact.
130-132
847-861
2001
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1
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1
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1
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3
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1
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1
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3
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347836
Krook
Three-dimensional model of NAD ...
Homo sapiens
FEBS Lett.
322
139-142
1993
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1
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1
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348018
Krook
Carboxyethyllysine in a protei ...
Homo sapiens
Proc. Natl. Acad. Sci. USA
90
502-506
1993
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1
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1
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1
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1
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1
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1
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1
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348017
Jarabak
Substrate specificity of three ...
Homo sapiens
Prostaglandins
26
849-868
1983
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1
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1
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1
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1
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348012
Korff
Isolation and properties of an ...
Oryctolagus cuniculus
Methods Enzymol.
86
152-155
1982
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1
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2
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1
1
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2
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1
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2
1
1
7
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1
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1
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2
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2
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1
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2
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1
1
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1
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2
1
1
7
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1
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1
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348013
Korff
The purification and character ...
Oryctolagus cuniculus
J. Biol. Chem.
257
2177-2181
1982
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-
-
-
-
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2
5
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2
1
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2
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1
1
1
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2
1
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5
1
1
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1
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2
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2
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2
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5
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2
1
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1
1
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2
1
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5
1
1
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1
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