BRENDA - Enzyme Database show
show all sequences of 1.1.1.228

Metabolism of monoterpenes: Specificity of the dehydrogenases responsible for the biosynthesis of camphor, 3-thujone, and 3-isothujone

Dehal, S.S.; Croteau, R.; Arch. Biochem. Biophys. 258, 287-291 (1987)

Data extracted from this reference:

General Stability
General Stability
Organism
stable to lyophilization
Salvia officinalis
stable to lyophilization
Tanacetum vulgare
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
70000
-
gel filtration
Tanacetum vulgare
92000
-
gel filtration
Salvia officinalis
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(+)-cis-sabinol + NAD+
Salvia officinalis
pathway in the biosynthesis of (-)-3-isothujone (sage) or (+)-3-thujone (tansy)
(+)-sabinone + NADH
-
Salvia officinalis
?
(+)-cis-sabinol + NAD+
Tanacetum vulgare
pathway in the biosynthesis of (-)-3-isothujone (sage) or (+)-3-thujone (tansy)
(+)-sabinone + NADH
-
Tanacetum vulgare
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Salvia officinalis
-
sage
-
Tanacetum vulgare
-
tansy
-
Purification (Commentary)
Commentary
Organism
partial
Salvia officinalis
partial
Tanacetum vulgare
Source Tissue
Source Tissue
Commentary
Organism
Textmining
leaf epidermis
oil glands
Salvia officinalis
-
leaf epidermis
oil glands
Tanacetum vulgare
-
Storage Stability
Storage Stability
Organism
-40°C, lyophilized, under argon, stable for several months without deterioration
Salvia officinalis
-40°C, lyophilized, under argon, stable for several months without deterioration
Tanacetum vulgare
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(+)-cis-sabinol + NAD+
-
286162
Salvia officinalis
(+)-sabinone + NADH
-
286162
Salvia officinalis
?
(+)-cis-sabinol + NAD+
-
286162
Tanacetum vulgare
(+)-sabinone + NADH
-
286162
Tanacetum vulgare
?
(+)-cis-sabinol + NAD+
pathway in the biosynthesis of (-)-3-isothujone (sage) or (+)-3-thujone (tansy)
286162
Salvia officinalis
(+)-sabinone + NADH
-
286162
Salvia officinalis
?
(+)-cis-sabinol + NAD+
pathway in the biosynthesis of (-)-3-isothujone (sage) or (+)-3-thujone (tansy)
286162
Tanacetum vulgare
(+)-sabinone + NADH
-
286162
Tanacetum vulgare
?
Cofactor
Cofactor
Commentary
Organism
Structure
additional information
flavin nucleotides are ineffective
Salvia officinalis
additional information
flavin nucleotides are ineffective
Tanacetum vulgare
NAD+
-
Salvia officinalis
NAD+
-
Tanacetum vulgare
NADP+
65-85% as effective as NAD+
Salvia officinalis
NADP+
65-85% as effective as NAD+
Tanacetum vulgare
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
additional information
flavin nucleotides are ineffective
Salvia officinalis
additional information
flavin nucleotides are ineffective
Tanacetum vulgare
NAD+
-
Salvia officinalis
NAD+
-
Tanacetum vulgare
NADP+
65-85% as effective as NAD+
Salvia officinalis
NADP+
65-85% as effective as NAD+
Tanacetum vulgare
General Stability (protein specific)
General Stability
Organism
stable to lyophilization
Salvia officinalis
stable to lyophilization
Tanacetum vulgare
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
70000
-
gel filtration
Tanacetum vulgare
92000
-
gel filtration
Salvia officinalis
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(+)-cis-sabinol + NAD+
Salvia officinalis
pathway in the biosynthesis of (-)-3-isothujone (sage) or (+)-3-thujone (tansy)
(+)-sabinone + NADH
-
Salvia officinalis
?
(+)-cis-sabinol + NAD+
Tanacetum vulgare
pathway in the biosynthesis of (-)-3-isothujone (sage) or (+)-3-thujone (tansy)
(+)-sabinone + NADH
-
Tanacetum vulgare
?
Purification (Commentary) (protein specific)
Commentary
Organism
partial
Salvia officinalis
partial
Tanacetum vulgare
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
leaf epidermis
oil glands
Salvia officinalis
-
leaf epidermis
oil glands
Tanacetum vulgare
-
Storage Stability (protein specific)
Storage Stability
Organism
-40°C, lyophilized, under argon, stable for several months without deterioration
Salvia officinalis
-40°C, lyophilized, under argon, stable for several months without deterioration
Tanacetum vulgare
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(+)-cis-sabinol + NAD+
-
286162
Salvia officinalis
(+)-sabinone + NADH
-
286162
Salvia officinalis
?
(+)-cis-sabinol + NAD+
-
286162
Tanacetum vulgare
(+)-sabinone + NADH
-
286162
Tanacetum vulgare
?
(+)-cis-sabinol + NAD+
pathway in the biosynthesis of (-)-3-isothujone (sage) or (+)-3-thujone (tansy)
286162
Salvia officinalis
(+)-sabinone + NADH
-
286162
Salvia officinalis
?
(+)-cis-sabinol + NAD+
pathway in the biosynthesis of (-)-3-isothujone (sage) or (+)-3-thujone (tansy)
286162
Tanacetum vulgare
(+)-sabinone + NADH
-
286162
Tanacetum vulgare
?
Other publictions for EC 1.1.1.228
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
286162
Dehal
Metabolism of monoterpenes: Sp ...
Salvia officinalis, Tanacetum vulgare
Arch. Biochem. Biophys.
258
287-291
1987
-
-
-
-
-
2
-
-
-
-
2
2
-
2
-
-
2
-
-
2
-
2
4
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
6
-
-
2
-
-
-
-
-
-
2
2
-
-
-
2
-
2
-
2
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-