BRENDA - Enzyme Database show
show all sequences of 1.1.1.226

Metabolism of cyclohexane caroxylic acid by Alcaligenes strain W1

Taylor, D.G.; Trudgill, P.; J. Bacteriol. 5, 401-411 (1978)
No PubMed abstract available

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
trans-4-hydroxycyclohexanecarboxylate + NAD+
Alcaligenes sp.
enzyme of the oxidative branch of the 2-hydroxy-4-carboxymucoic semialdehyde-cleaving pathway
4-oxocyclohexanecarboxylate + NADH
-
Alcaligenes sp.
-
trans-4-hydroxycyclohexanecarboxylate + NAD+
Alcaligenes sp. W1
enzyme of the oxidative branch of the 2-hydroxy-4-carboxymucoic semialdehyde-cleaving pathway
4-oxocyclohexanecarboxylate + NADH
-
Alcaligenes sp. W1
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Alcaligenes sp.
-
strain W1
-
Alcaligenes sp. W1
-
strain W1
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
trans-4-hydroxycyclohexanecarboxylate + NAD+
-
389503
Alcaligenes sp.
4-oxocyclohexanecarboxylate + NADH
-
389503
Alcaligenes sp.
-
trans-4-hydroxycyclohexanecarboxylate + NAD+
enzyme of the oxidative branch of the 2-hydroxy-4-carboxymucoic semialdehyde-cleaving pathway
389503
Alcaligenes sp.
4-oxocyclohexanecarboxylate + NADH
-
389503
Alcaligenes sp.
-
trans-4-hydroxycyclohexanecarboxylate + NAD+
-
389503
Alcaligenes sp. W1
4-oxocyclohexanecarboxylate + NADH
-
389503
Alcaligenes sp. W1
-
trans-4-hydroxycyclohexanecarboxylate + NAD+
enzyme of the oxidative branch of the 2-hydroxy-4-carboxymucoic semialdehyde-cleaving pathway
389503
Alcaligenes sp. W1
4-oxocyclohexanecarboxylate + NADH
-
389503
Alcaligenes sp. W1
-
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.2
-
NADH oxidation
Alcaligenes sp.
10
-
NAD reduction
Alcaligenes sp.
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
very specific, no activity with NADP+
Alcaligenes sp.
NADH
very specific, no activity with NADPH
Alcaligenes sp.
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
very specific, no activity with NADP+
Alcaligenes sp.
NADH
very specific, no activity with NADPH
Alcaligenes sp.
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
trans-4-hydroxycyclohexanecarboxylate + NAD+
Alcaligenes sp.
enzyme of the oxidative branch of the 2-hydroxy-4-carboxymucoic semialdehyde-cleaving pathway
4-oxocyclohexanecarboxylate + NADH
-
Alcaligenes sp.
-
trans-4-hydroxycyclohexanecarboxylate + NAD+
Alcaligenes sp. W1
enzyme of the oxidative branch of the 2-hydroxy-4-carboxymucoic semialdehyde-cleaving pathway
4-oxocyclohexanecarboxylate + NADH
-
Alcaligenes sp. W1
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
trans-4-hydroxycyclohexanecarboxylate + NAD+
-
389503
Alcaligenes sp.
4-oxocyclohexanecarboxylate + NADH
-
389503
Alcaligenes sp.
-
trans-4-hydroxycyclohexanecarboxylate + NAD+
enzyme of the oxidative branch of the 2-hydroxy-4-carboxymucoic semialdehyde-cleaving pathway
389503
Alcaligenes sp.
4-oxocyclohexanecarboxylate + NADH
-
389503
Alcaligenes sp.
-
trans-4-hydroxycyclohexanecarboxylate + NAD+
-
389503
Alcaligenes sp. W1
4-oxocyclohexanecarboxylate + NADH
-
389503
Alcaligenes sp. W1
-
trans-4-hydroxycyclohexanecarboxylate + NAD+
enzyme of the oxidative branch of the 2-hydroxy-4-carboxymucoic semialdehyde-cleaving pathway
389503
Alcaligenes sp. W1
4-oxocyclohexanecarboxylate + NADH
-
389503
Alcaligenes sp. W1
-
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.2
-
NADH oxidation
Alcaligenes sp.
10
-
NAD reduction
Alcaligenes sp.
Other publictions for EC 1.1.1.226
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
389502
Obata
Purification and properties of ...
Corynebacterium cyclohexanicum
Eur. J. Biochem.
174
451-458
1988
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4
4
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2
1
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2
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1
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3
1
3
1
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2
1
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2
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2
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4
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4
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2
1
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1
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3
1
3
1
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2
1
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-
-
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389503
Taylor
-
Metabolism of cyclohexane caro ...
Alcaligenes sp., Alcaligenes sp. W1
J. Bacteriol.
5
401-411
1978
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2
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2
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4
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2
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2
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2
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2
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4
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2
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