BRENDA - Enzyme Database show
show all sequences of 1.1.1.222

In vitro tryptophan catabolism by Leishmania donovani donovani promastigotes

Leelayoova, S.; Marbury, D.; Rainey, P.M.; MacKenzie, N.E.; Hall, J.E.; J. Protozool. 39, 350-358 (1992)

Data extracted from this reference:

Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Mn2+
required
Leishmania donovani donovani
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3-(4-hydroxyphenyl)pyruvate + NAD(P)H
Leishmania donovani donovani
involved in aromatic amino acid catabolism
(R)-3-(4-hydroxyphenyl)lactate + NAD(P)+
-
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Leishmania donovani donovani
-
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3-(4-hydroxyphenyl)pyruvate + NAD(P)H
-
286313
Leishmania donovani donovani
(R)-3-(4-hydroxyphenyl)lactate + NAD(P)+
-
-
-
r
3-(4-hydroxyphenyl)pyruvate + NAD(P)H
involved in aromatic amino acid catabolism
286313
Leishmania donovani donovani
(R)-3-(4-hydroxyphenyl)lactate + NAD(P)+
-
-
-
-
indolepyruvate + NAD(P)H
-
286313
Leishmania donovani donovani
indolelactate + NAD(P)+
-
286313
Leishmania donovani donovani
r
Cofactor
Cofactor
Commentary
Organism
Structure
NADH
-
Leishmania donovani donovani
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADH
-
Leishmania donovani donovani
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Mn2+
required
Leishmania donovani donovani
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3-(4-hydroxyphenyl)pyruvate + NAD(P)H
Leishmania donovani donovani
involved in aromatic amino acid catabolism
(R)-3-(4-hydroxyphenyl)lactate + NAD(P)+
-
-
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3-(4-hydroxyphenyl)pyruvate + NAD(P)H
-
286313
Leishmania donovani donovani
(R)-3-(4-hydroxyphenyl)lactate + NAD(P)+
-
-
-
r
3-(4-hydroxyphenyl)pyruvate + NAD(P)H
involved in aromatic amino acid catabolism
286313
Leishmania donovani donovani
(R)-3-(4-hydroxyphenyl)lactate + NAD(P)+
-
-
-
-
indolepyruvate + NAD(P)H
-
286313
Leishmania donovani donovani
indolelactate + NAD(P)+
-
286313
Leishmania donovani donovani
r
Other publictions for EC 1.1.1.222
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
286313
Leelayoova
In vitro tryptophan catabolism ...
Leishmania donovani donovani
J. Protozool.
39
350-358
1992
-
-
-
-
-
-
-
-
-
1
-
1
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286312
Bode
-
Purification and properties of ...
Candida maltosa
Biochem. Physiol. Pflanz.
181
189-198
1986
-
-
-
-
-
1
2
9
-
3
3
1
-
1
-
-
1
-
-
-
2
-
8
1
1
1
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
2
-
9
-
3
3
1
-
-
-
1
-
-
2
-
8
1
1
1
1
-
2
-
-
-
-
-
-
-
-
-