BRENDA - Enzyme Database show
show all sequences of 1.1.1.216

Farnesol oxidation in insects: evidence that the biosynthesis of insect juvenile hormone is mediated by a specific alcohol oxidase

Sperry, A.E.; Sen, S.E.; Insect Biochem. Mol. Biol. 31, 171-178 (2001)

Data extracted from this reference:

Activating Compound
Activating Compound
Commentary
Organism
Structure
FAD
slightly enhances activity
Manduca sexta
Inhibitors
Inhibitors
Commentary
Organism
Structure
1,10-phenanthroline
weak irreversible inhibitor
Manduca sexta
Cu2+
-
Manduca sexta
glucose oxidase
-
Manduca sexta
Sodium dithionite
-
Manduca sexta
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.001
-
farnesol
-
Manduca sexta
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
farnesol + NADP+
Manduca sexta
-
farnesal + NADPH
-
Manduca sexta
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Manduca sexta
-
tobacco hornworm
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
corpus allatum
-
Manduca sexta
-
larva
-
Manduca sexta
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
farnesol + NADP+
-
347994
Manduca sexta
farnesal + NADPH
-
347994
Manduca sexta
?
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6
7
-
Manduca sexta
Activating Compound (protein specific)
Activating Compound
Commentary
Organism
Structure
FAD
slightly enhances activity
Manduca sexta
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
1,10-phenanthroline
weak irreversible inhibitor
Manduca sexta
Cu2+
-
Manduca sexta
glucose oxidase
-
Manduca sexta
Sodium dithionite
-
Manduca sexta
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.001
-
farnesol
-
Manduca sexta
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
farnesol + NADP+
Manduca sexta
-
farnesal + NADPH
-
Manduca sexta
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
corpus allatum
-
Manduca sexta
-
larva
-
Manduca sexta
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
farnesol + NADP+
-
347994
Manduca sexta
farnesal + NADPH
-
347994
Manduca sexta
?
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6
7
-
Manduca sexta
Other publictions for EC 1.1.1.216
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
713402
Mayoral
NADP+-dependent farnesol dehyd ...
Aedes aegypti
Proc. Natl. Acad. Sci. USA
106
21091-21096
2009
-
-
1
-
-
-
-
7
-
-
2
-
-
1
-
-
1
-
-
7
2
-
8
1
-
-
-
-
1
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
7
-
-
2
-
-
-
-
1
-
7
2
-
8
1
-
-
-
-
1
-
-
-
1
-
-
1
-
-
347994
Sperry
Farnesol oxidation in insects: ...
Manduca sexta
Insect Biochem. Mol. Biol.
31
171-178
2001
1
-
-
-
-
-
4
1
-
-
-
1
-
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
4
-
1
-
-
-
1
-
-
-
-
-
2
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
347993
Inoue
Characterization and activity ...
Ipomoea batatas
Agric. Biol. Chem.
48
733-738
1984
-
-
-
-
-
-
6
2
-
-
2
-
-
1
-
-
1
-
-
1
-
-
6
1
1
-
-
-
2
2
-
1
-
-
-
-
-
-
1
-
-
-
-
6
-
2
-
-
2
-
-
-
-
1
-
1
-
-
6
1
1
-
-
-
2
2
-
-
-
-
-
-
-
-