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show all sequences of 1.1.1.210

Identification of histidine residue in the active site of fetal lamb 3beta,20alpha-hydroxysteroid oxidoreductase

Chen, Q.; Sweet, F.; Sheng Wu Hua Xue Yu Sheng Wu Wu Li Jin Zhan 18, 113-117 (1991)
No PubMed abstract available

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
5alpha-dihydrotestosterone 17-bromoacetate
competitive inhibition of 3beta- and 20alpha-reductase activity, time dependent and simultaneous, complete inactivation
Ovis aries
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
soluble
-
Ovis aries
-
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Ovis aries
-
-
-
Reaction
Reaction
Commentary
Organism
5alpha-androstan-3beta,17beta-diol + NADP+ = 17beta-hydroxy-5alpha-androstan-3-one + NADPH + H+
3beta and 20alpha substrates share the same active site
Ovis aries
Source Tissue
Source Tissue
Commentary
Organism
Textmining
erythrocyte
fetal
Ovis aries
-
Cofactor
Cofactor
Commentary
Organism
Structure
NADP+
-
Ovis aries
NADPH
-
Ovis aries
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADP+
-
Ovis aries
NADPH
-
Ovis aries
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
5alpha-dihydrotestosterone 17-bromoacetate
competitive inhibition of 3beta- and 20alpha-reductase activity, time dependent and simultaneous, complete inactivation
Ovis aries
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
soluble
-
Ovis aries
-
-
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
erythrocyte
fetal
Ovis aries
-
Other publictions for EC 1.1.1.210
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
657329
Clementi
Luteal 3beta-hydroxysteroid de ...
Rattus norvegicus
Reprod. Biol. Endocrinol.
2
22
2004
-
-
-
-
-
-
-
-
1
-
-
1
-
1
-
-
-
-
-
1
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1
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1
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1
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1
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1
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1
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1
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-
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1
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1
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1
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1
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286268
Chen
-
Identification of histidine re ...
Ovis aries
Sheng Wu Hua Xue Yu Sheng Wu Wu Li Jin Zhan
18
113-117
1991
-
-
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1
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1
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1
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1
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1
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2
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2
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1
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1
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1
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-
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286267
Chen
Fetal lamb 3beta,20alpha-hydro ...
Ovis aries
Biochemistry
28
8856-8863
1989
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-
-
-
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1
1
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2
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1
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1
1
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1
1
1
2
1
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2
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2
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1
1
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1
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1
1
1
2
1
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286266
Chen
Isolation of 3beta,20alpha-hyd ...
Ovis aries
Steroids
49
477-496
1987
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-
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-
-
2
3
2
1
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2
2
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1
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1
1
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1
1
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3
1
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2
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2
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2
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3
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2
1
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2
2
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1
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3
1
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286265
Sharaf
Dual activity at an enzyme act ...
Bos taurus
Biochemistry
21
4615-4620
1982
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1
3
2
1
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1
2
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1
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3
1
1
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2
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1
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1
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3
1
1
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