BRENDA - Enzyme Database show
show all sequences of 1.1.1.207

Metabolism of monoterpenes: Conversion of l-menthone tol-menthole and d-neomenthol by stereospecific dehydrogenases from peppermint (Mentha piperita) leaves

Kjonaas, R.; Martinkus-Taylor, C.; Croteau, R.; Plant Physiol. 69, 1013-1017 (1982)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
Hg2+
almost complete inhibition at 0.25 mM
Mentha x piperita
iodoacetamide
almost complete inhibition at 0.25 mM
Mentha x piperita
N-ethylmaleimide
almost complete inhibition at 0.25 mM
Mentha x piperita
p-hydroxymercuribenzoate
almost complete inhibition at 0.05 mM
Mentha x piperita
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.015
-
NADPH
-
Mentha x piperita
0.25
-
(-)-menthone
-
Mentha x piperita
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
35000
-
gel filtration
Mentha x piperita
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(1R)-menthone + NADPH
Mentha x piperita
?
(1R)-menthole + NADP+
-
Mentha x piperita
-
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Mentha x piperita
-
peppermint
-
Purification (Commentary)
Commentary
Organism
-
Mentha x piperita
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(-)-menthone + NADPH
-
347974
Mentha x piperita
(3R)-menthol + NADP+
-
-
-
-
(1R)-menthone + NADPH
ir
347974
Mentha x piperita
(1R)-menthol + NADP+
-
347974
Mentha x piperita
-
(1R)-menthone + NADPH
?
347974
Mentha x piperita
(1R)-menthole + NADP+
-
347974
Mentha x piperita
-
d-isomenthone + NADPH
?
347974
Mentha x piperita
d-neoisomenthol + NADP+
-
347974
Mentha x piperita
-
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.5
-
(-)-menthone + NADPH
Mentha x piperita
Cofactor
Cofactor
Commentary
Organism
Structure
NADPH
NADH far less effective
Mentha x piperita
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADPH
NADH far less effective
Mentha x piperita
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
Hg2+
almost complete inhibition at 0.25 mM
Mentha x piperita
iodoacetamide
almost complete inhibition at 0.25 mM
Mentha x piperita
N-ethylmaleimide
almost complete inhibition at 0.25 mM
Mentha x piperita
p-hydroxymercuribenzoate
almost complete inhibition at 0.05 mM
Mentha x piperita
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.015
-
NADPH
-
Mentha x piperita
0.25
-
(-)-menthone
-
Mentha x piperita
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
35000
-
gel filtration
Mentha x piperita
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
(1R)-menthone + NADPH
Mentha x piperita
?
(1R)-menthole + NADP+
-
Mentha x piperita
-
Purification (Commentary) (protein specific)
Commentary
Organism
-
Mentha x piperita
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
(-)-menthone + NADPH
-
347974
Mentha x piperita
(3R)-menthol + NADP+
-
-
-
-
(1R)-menthone + NADPH
ir
347974
Mentha x piperita
(1R)-menthol + NADP+
-
347974
Mentha x piperita
-
(1R)-menthone + NADPH
?
347974
Mentha x piperita
(1R)-menthole + NADP+
-
347974
Mentha x piperita
-
d-isomenthone + NADPH
?
347974
Mentha x piperita
d-neoisomenthol + NADP+
-
347974
Mentha x piperita
-
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.5
-
(-)-menthone + NADPH
Mentha x piperita
Other publictions for EC 1.1.1.207
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
726206
Bose
Effect of gibberellic acid and ...
Mentha arvensis
Plant Physiol. Biochem.
66
150-158
2013
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
670590
Davis
Monoterpene metabolism. Clonin ...
Mentha x piperita
Plant Physiol.
137
873-881
2005
-
-
1
-
-
-
-
3
-
-
1
3
-
1
-
-
1
-
-
2
-
-
5
1
1
-
-
2
1
1
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
3
-
-
1
3
-
-
-
1
-
2
-
-
5
1
1
-
-
2
1
1
-
-
-
-
-
-
-
-
347974
Kjonaas
Metabolism of monoterpenes: Co ...
Mentha x piperita
Plant Physiol.
69
1013-1017
1982
-
-
-
-
-
-
4
2
-
-
1
1
-
1
-
-
1
-
-
-
-
-
4
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
4
-
2
-
-
1
1
-
-
-
1
-
-
-
-
4
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
347975
Croteau
Demonstration of the intercell ...
Mentha x piperita
Plant Physiol.
69
975-977
1982
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-