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show all sequences of 1.1.1.202

Efficient production of 1,3-propanediol from glycerol upon constitutive expression of the 1,3-propanediol oxidoreductase gene in engineered Klebsiella pneumoniae with elimination of by-product formation

Oh, B.R.; Seo, J.W.; Heo, S.Y.; Luo, L.H.; Hong, W.K.; Park, D.H.; Kim, C.H.; Bioprocess Biosyst. Eng. 36, 757-763 (2013)

Data extracted from this reference:

Application
Application
Commentary
Organism
synthesis
genetic engineering of Klebsiella pneumoniae for production of 1.3-propanediol from glycerol. Constitutive expression of the dhaT gene alone gives the highest yield, fed-batch fermentation results in efficient production of 1,3-propanediol from either pure or crude glycerol, without by-product formation
Klebsiella pneumoniae
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1,3-propanediol + NAD+
Klebsiella pneumoniae
-
3-hydroxypropanal + NADH + H+
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Klebsiella pneumoniae
Q59477
-
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1,3-propanediol + NAD+
-
724566
Klebsiella pneumoniae
3-hydroxypropanal + NADH + H+
-
-
-
?
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
-
Klebsiella pneumoniae
NADH
-
Klebsiella pneumoniae
Application (protein specific)
Application
Commentary
Organism
synthesis
genetic engineering of Klebsiella pneumoniae for production of 1.3-propanediol from glycerol. Constitutive expression of the dhaT gene alone gives the highest yield, fed-batch fermentation results in efficient production of 1,3-propanediol from either pure or crude glycerol, without by-product formation
Klebsiella pneumoniae
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
-
Klebsiella pneumoniae
NADH
-
Klebsiella pneumoniae
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
1,3-propanediol + NAD+
Klebsiella pneumoniae
-
3-hydroxypropanal + NADH + H+
-
-
?
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
1,3-propanediol + NAD+
-
724566
Klebsiella pneumoniae
3-hydroxypropanal + NADH + H+
-
-
-
?
Other publictions for EC 1.1.1.202
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
721395
Elleuche
Structural and biochemical cha ...
Oenococcus oeni, Oenococcus oeni ATCC BAA-1163
Appl. Microbiol. Biotechnol.
97
8963-8975
2013
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1
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4
724566
Oh
Efficient production of 1,3-pr ...
Klebsiella pneumoniae
Bioprocess Biosyst. Eng.
36
757-763
2013
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725951
Qi
Molecular cloning, co-expressi ...
Citrobacter freundii
Mol. Biotechnol.
54
469-474
2013
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1
2
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2
2
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725880
Stevens
1,3-Propanediol dehydrogenases ...
Lactobacillus reuteri
Microb. Cell Fact.
10
61
2011
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1
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695716
Ma
Construction of a Novel Expres ...
Klebsiella pneumoniae
Appl. Biochem. Biotechnol.
162
399-407
2010
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1
1
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710747
Jeyakanthan
Expression, purification and X ...
Aquifex aeolicus
Acta Crystallogr. Sect. F
66
184-186
2010
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1
1
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1
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1
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710972
Zhuge
Expression of 1,3-propanediol ...
Escherichia coli, Klebsiella pneumoniae
Appl. Microbiol. Biotechnol.
87
2177-2184
2010
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2
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712531
Ma
Relaxing the coenzyme specific ...
Klebsiella pneumoniae
J. Biotechnol.
146
173-178
2010
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1
2
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1
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4
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6
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6
6
695764
Tang
Microbial conversion of glycer ...
Escherichia coli, Escherichia coli SYU
Appl. Environ. Microbiol.
75
1628-1634
2009
1
1
1
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6
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695842
Seo
Elimination of by-product form ...
Klebsiella pneumoniae, Klebsiella pneumoniae Cu
Appl. Microbiol. Biotechnol.
84
527-534
2009
1
-
1
-
1
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3
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2
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-
695844
Seo
Identification and utilization ...
Escherichia coli, Klebsiella pneumoniae
Appl. Microbiol. Biotechnol.
85
659-666
2009
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1
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1
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1
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696785
Zhao
Effects of over-expression of ...
Klebsiella pneumoniae
Bioprocess Biosyst. Eng.
32
313-320
2009
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1
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697666
Chen
-
Regulation of 3-hydroxypropion ...
Klebsiella pneumoniae
Enzyme Microb. Technol.
45
305-309
2009
2
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1
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1
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1
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698602
Marcal
1,3-Propanediol dehydrogenase ...
Klebsiella pneumoniae
J. Bacteriol.
191
1143-1151
2009
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1
1
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1
1
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2
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2
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699149
Zhao
-
Over-expression of glycerol de ...
Klebsiella pneumoniae
J. Chem. Technol. Biotechnol.
84
626-632
2009
1
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1
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684524
Nemeth
Development of a new bioproces ...
Klebsiella pneumoniae
Appl. Biochem. Biotechnol.
144
47-58
2008
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1
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1
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1
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688171
Hao
Decrease of 3-hydroxypropional ...
Klebsiella pneumoniae, Klebsiella pneumoniae TUAC01
J. Ind. Microbiol. Biotechnol.
35
735-741
2008
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1
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1
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4
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699357
Hao
3-Hydroxypropionaldehyde guide ...
Klebsiella pneumoniae
J. Ind. Microbiol. Biotechnol.
35
1615-1624
2008
1
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1
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1
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675901
Wang
Production of 1,3-propanediol ...
Klebsiella pneumoniae
Mol. Biotechnol.
37
112-119
2007
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684171
Marcal
Crystallization and preliminar ...
Klebsiella pneumoniae
Acta Crystallogr. Sect. F
63
249-251
2007
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1
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667270
Gonzalez-Pajuelo
Microbial conversion of glycer ...
Clostridium butyricum, Clostridium butyricum VPI 3266
Appl. Environ. Microbiol.
72
96-101
2006
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1
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664422
Lin
Enhancement of 1,3-propanediol ...
Klebsiella pneumoniae, Klebsiella pneumoniae M5a1
Biotechnol. Lett.
27
1755-1759
2005
1
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12
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1
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670216
Fenghuan
High-level expression of the 1 ...
Klebsiella pneumoniae
Mol. Biotechnol.
31
211-219
2005
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1
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2
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1
1
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4
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1
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1
1
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1
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2
1
1
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1
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655107
Zheng
Cloning and sequence analysis ...
Klebsiella pneumoniae
Biotechnol. Lett.
26
251-255
2004
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657320
Schwarzenbacher
Crystal structure of an iron-c ...
Thermotoga maritima
Proteins
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2003
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657406
Nemeth
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1,3-Propanediol oxidoreductase ...
Klebsiella pneumoniae, Klebsiella pneumoniae DSM 2026
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2003
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389496
Malaoui
Purification and characterizat ...
Clostridium butyricum, Clostridium butyricum E5
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2000
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Abbad-Andaloussi
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Clostridium butyricum
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1998
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Luers
Glycerol conversion to 1,3-pro ...
Clostridium pasteurianum
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1997
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389498
Veiga-da-Cunha
1,3-Propanediol:NAD+ oxidoredu ...
Lactobacillus brevis, Lactobacillus buchneri
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1992
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389489
Heyndrickx
-
The fermentation of glycerol b ...
Clostridium butyricum, Clostridium butyricum LMG 1212t2, Clostridium pasteurianum, Clostridium pasteurianum LMG 3285
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Talarico
Utilization of glycerol as a h ...
Lactobacillus reuteri
Appl. Environ. Microbiol.
56
943-948
1990
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Sprenger
Anaerobic growth of Escherichi ...
Klebsiella pneumoniae
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1989
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Klebsiella pneumoniae 1,3-prop ...
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Abeles
beta-Hydroxypropionaldehyde, a ...
Klebsiella pneumoniae
Biochim. Biophys. Acta
41
530-531
1960
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