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show all sequences of 1.1.1.200

Regulation of apple leaf aldose-6-phosphate reductase activity by inorganic phosphate and divalent cations

Zhou, R.; Sicher, R.C.; Cheng, L.; Quebedeaux, B.; Funct. Plant Biol. 30, 1037-1043 (2003)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
CaCl2
2.5 mM, in presence of 50 mM substrate, 12% decrease in activity
Malus domestica
CuCl2
-
Malus domestica
MgCl2
2.5 mM, in presence of 50 mM substrate, 12% decrease in activity
Malus domestica
phosphate
mixed-type inhibition
Malus domestica
ZnCl2
2 mM, 58% inhibition, partially reversible by EDTA
Malus domestica
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
1.7
-
D-sorbitol-6-phosphate
pH 9.0
Malus domestica
3
-
D-sorbitol-6-phosphate
pH 9.0
Malus domestica
5.1
-
D-Glucose-6-phosphate
pH 9.0, presence of 2.5 mM MgCl2
Malus domestica
9.8
-
D-Glucose-6-phosphate
pH 9.0
Malus domestica
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
CaCl2
2.5 mM, in presence of 5 mM substrate, 40% increase in activity
Malus domestica
MgCl2
2.5 mM, in presence of 5 mM substrate, 52% increase in activity
Malus domestica
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
33000
-
2 * 33000, SDS-PAGE
Malus domestica
68000
-
gel filtration
Malus domestica
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Malus domestica
-
Borkh. cv. Gala
-
Purification (Commentary)
Commentary
Organism
-
Malus domestica
Source Tissue
Source Tissue
Commentary
Organism
Textmining
leaf
fully developed
Malus domestica
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
7.94
-
pH 9.0
Malus domestica
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-glucose 6-phosphate + NADPH
-
655664
Malus domestica
D-sorbitol 6-phosphate + NADP+
-
-
-
r
D-sorbitol 6-phosphate + NADP+
-
655664
Malus domestica
D-glucose 6-phosphate + NADPH + H+
-
-
-
r
Subunits
Subunits
Commentary
Organism
dimer
2 * 33000, SDS-PAGE
Malus domestica
Cofactor
Cofactor
Commentary
Organism
Structure
NADP+
-
Malus domestica
NADPH
-
Malus domestica
Ki Value [mM]
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
0.42
-
phosphate
pH 9.0
Malus domestica
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADP+
-
Malus domestica
NADPH
-
Malus domestica
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
CaCl2
2.5 mM, in presence of 50 mM substrate, 12% decrease in activity
Malus domestica
CuCl2
-
Malus domestica
MgCl2
2.5 mM, in presence of 50 mM substrate, 12% decrease in activity
Malus domestica
phosphate
mixed-type inhibition
Malus domestica
ZnCl2
2 mM, 58% inhibition, partially reversible by EDTA
Malus domestica
Ki Value [mM] (protein specific)
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
0.42
-
phosphate
pH 9.0
Malus domestica
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
1.7
-
D-sorbitol-6-phosphate
pH 9.0
Malus domestica
3
-
D-sorbitol-6-phosphate
pH 9.0
Malus domestica
5.1
-
D-Glucose-6-phosphate
pH 9.0, presence of 2.5 mM MgCl2
Malus domestica
9.8
-
D-Glucose-6-phosphate
pH 9.0
Malus domestica
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
CaCl2
2.5 mM, in presence of 5 mM substrate, 40% increase in activity
Malus domestica
MgCl2
2.5 mM, in presence of 5 mM substrate, 52% increase in activity
Malus domestica
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
33000
-
2 * 33000, SDS-PAGE
Malus domestica
68000
-
gel filtration
Malus domestica
Purification (Commentary) (protein specific)
Commentary
Organism
-
Malus domestica
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
leaf
fully developed
Malus domestica
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
7.94
-
pH 9.0
Malus domestica
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-glucose 6-phosphate + NADPH
-
655664
Malus domestica
D-sorbitol 6-phosphate + NADP+
-
-
-
r
D-sorbitol 6-phosphate + NADP+
-
655664
Malus domestica
D-glucose 6-phosphate + NADPH + H+
-
-
-
r
Subunits (protein specific)
Subunits
Commentary
Organism
dimer
2 * 33000, SDS-PAGE
Malus domestica
Other publictions for EC 1.1.1.200
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
696497
Figueroa
Aldose-6-phosphate reductase f ...
Malus domestica
Biochimie
92
81-88
2010
-
-
1
-
-
-
5
-
1
-
3
-
-
3
-
-
1
-
-
1
3
1
3
2
-
-
-
4
-
1
-
-
-
-
-
-
-
1
-
-
-
-
-
5
-
-
1
-
3
-
-
-
-
1
-
1
3
1
3
2
-
-
-
4
-
1
-
-
-
-
-
-
-
-
686514
Li
-
Enzymatic regulation of sorbit ...
Malus domestica
Eur. J. Hort. Sci.
72
12-19
2007
1
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
690167
Li
Photosynthesis in response to ...
Prunus persica
Tree Physiol.
27
1307-1318
2007
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
682461
Cheng
Antisense inhibition of sorbit ...
Malus domestica
Planta
220
767-776
2005
-
-
1
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
655664
Zhou
Regulation of apple leaf aldos ...
Malus domestica
Funct. Plant Biol.
30
1037-1043
2003
-
-
-
-
-
-
5
4
-
2
2
-
-
1
-
-
1
-
-
1
1
-
2
1
-
-
-
-
-
-
-
2
1
-
-
-
-
-
2
-
-
-
-
5
1
4
-
2
2
-
-
-
-
1
-
1
1
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
347838
Loescher
Sorbitol metabolism and sink-s ...
Malus domestica
Plant Physiol.
70
335-339
1982
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
1
3
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
3
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
347839
Negm
Characterization and partial p ...
Malus domestica, Prunus armeniaca, Prunus persica, Pyrus communis
Plant Physiol.
67
139-142
1981
-
-
-
-
-
-
6
2
-
-
-
4
-
8
-
-
1
-
-
4
5
1
12
-
2
1
-
-
1
1
-
3
-
-
-
-
-
-
3
-
-
-
-
6
-
2
-
-
-
4
-
-
-
1
-
4
5
1
12
-
2
1
-
-
1
1
-
-
-
-
-
-
-
-