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Literature summary for 1.1.1.2 extracted from

  • Jing, K.; Xu, Y.; Liu, Y.; Jiang, X.; Peng, L.; Cen, P.
    Efficient production of recombinant aldehyde reductase and its application for asymmetric reduction of ethyl-4-chloro-3-oxobutanoate to ethyl (R)-4-hydoxybutanoate (2005), Prep. Biochem. Biotechnol., 35, 203-215.
    View publication on PubMed
Search for more literature for 1.1.1.2

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli M15, plasmid pQE30-ALR Sporidiobolus salmonicolor

Organism

Organism UniProt Comment Textmining
Sporidiobolus salmonicolor
-
 ZJUB 105
-
Sporidiobolus salmonicolor ZJUB 105
-
 ZJUB 105
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
6.48
-
 activity of ALR in Escherichia coli M15, the enzyme activity is fifteen times higher than thatof Sporobolomyces salmonicolor ZJUB 105 Sporidiobolus salmonicolor

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ethyl-4-chloro-3-oxobutanoate + NADPH + H+
-
 Sporidiobolus salmonicolor ethyl-4-chloro-3-hydroxybutanoate + NADP+
-
 ?
ethyl-4-chloro-3-oxobutanoate + NADPH + H+
-
 Sporidiobolus salmonicolor ZJUB 105 ethyl-4-chloro-3-hydroxybutanoate + NADP+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Sporidiobolus salmonicolor