Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.1.1.2 extracted from

  • Schracke, N.H.; Linne, U.; Christoph Mahlert, C.; Marahiel, M.A.
    Synthesis of linear gramicidin requires the cooperation of two independent reductases (2005), Biochemistry, 44, 8507-8513.
    View publication on PubMed
Search for more literature for 1.1.1.2

Cloned(Commentary)

Cloned (Comment) Organism
Escherichia coli BL21, LB-medium, supplied with kanamycin (0,05 mg/L final concentration) Brevibacillus brevis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Ac-D-Leu-L-Trp-D-Leu-L-Trp-Gly-S-CoA + NADPH + H+ Brevibacillus brevis
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Brevibacillus brevis
-
 ATCC 8185
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ac-D-Leu-D-Trp-D-Leu-D-Trp-Gly + NADH + H+
-
 Brevibacillus brevis Ac-D-Leu-D-Trp-D-Leu-D-Trp-Gly-al + NAD+ + H2O
-
 ?
Ac-D-Leu-D-Trp-D-Leu-D-Trp-Gly-al + NADPH + H+
-
 Brevibacillus brevis Ac-D-Leu-D-Trp-D-Leu-D-Trp-Gly-ol + NADP+
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-D-Ala + NADH + H+
-
 Brevibacillus brevis Ac-D-Leu-L-Trp-D-Leu-L-Trp-D-Ala-al + NAD+ + H2O
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-D-Ala-al + NADPH + H+
-
 Brevibacillus brevis Ac-D-Leu-L-Trp-D-Leu-L-Trp-D-Ala-ol + NADP+
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-Gly + NADH + H+
-
 Brevibacillus brevis Ac-D-Leu-L-Trp-D-Leu-L-Trp-Gly-al + NAD+ + H2O
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-Gly-al + NADPH + H+
-
 Brevibacillus brevis Ac-D-Leu-L-Trp-D-Leu-L-Trp-Gly-ol + NADP+
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-Gly-S-CoA + NADPH + H+
-
 Brevibacillus brevis ?
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Ala + NADH + H+
-
 Brevibacillus brevis Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Ala-al + NAD+ + H2O
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Ala-al + NADPH + H+
-
 Brevibacillus brevis Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Ala-ol + NADP+
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Asp + NADH + H+
-
 Brevibacillus brevis Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Asp-al + NAD+ + H2O
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Asp-al + NADPH + H+
-
 Brevibacillus brevis Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Asp-ol + NADP+
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Leu- + NADH + H+
-
 Brevibacillus brevis Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Leu-al + NAD+ + H2O
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Leu-al + NADPH + H+
-
 Brevibacillus brevis Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Leu-ol + NADP+
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Lys + NADH + H+
-
 Brevibacillus brevis Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Lys-al + NAD+ + H2O
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Lys-al + NADPH + H+
-
 Brevibacillus brevis Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Lys-ol + NADP+
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Phe + NADH + H+
-
 Brevibacillus brevis Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Phe-al + NAD+ + H2O
-
 ?
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Phe-al + NADPH + H+
-
 Brevibacillus brevis Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Phe-ol + NADP+
-
 ?
Ac-L-Leu-L-Trp-L-Leu-L-Trp-Gly- + NADH + H+
-
 Brevibacillus brevis Ac-L-Leu-L-Trp-L-Leu-L-Trp-Gly-al + NAD+ + H2O
-
 ?
Ac-L-Leu-L-Trp-L-Leu-L-Trp-Gly-al + NADPH + H+
-
 Brevibacillus brevis Ac-L-Leu-L-Trp-L-Leu-L-Trp-Gly-ol + NADP+
-
 ?

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Brevibacillus brevis
NADPH
-
 Brevibacillus brevis