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show all sequences of 1.1.1.2

Purification of acetaldehyde dehydrogenase and alcohol dehydrogenases from Thermoanaerobacter ethanolicus 39E and characterization of the secondary-alcohol dehydrogenase (2 degrees Adh) as a bifunctional alcohol dehydrogenase-acetyl-CoA reductive thioesterase

Burdette, D.; Zeikus, J.G.; Biochem. J. 302, 163-170 (1994)

Data extracted from this reference:

Application
Application
Commentary
Organism
synthesis
industrial ethanol production
Saccharomyces cerevisiae
synthesis
industrial ethanol production; potential use for industrial production of ethanol by fermentation, thermophilic fermentations offer the potential to separate ethanol from continous cultures at process temperature and reduced pressure during growth
Thermoanaerobacter ethanolicus
synthesis
industrial ethanol production
Zymomonas mobilis
Cloned(Commentary)
Commentary
Organism
1° Adh cloned and characterized
Clostridium acetobutylicum
1° Adh cloned and characterized
Escherichia coli
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.02
-
NADP+
1° Adh, ethanol as substrate
Thermoanaerobacter ethanolicus
0.025
-
NADH
1° Adh, acetaldehyde as substrate
Thermoanaerobacter ethanolicus
0.033
-
NADPH
2° Adh, propanone as substrate
Thermoanaerobacter ethanolicus
0.049
-
NADP+
2° Adh, butan-2-ol as substrate
Thermoanaerobacter ethanolicus
0.055
-
NADPH
2° Adh, acetaldehyde as substrate
Thermoanaerobacter ethanolicus
0.07
-
NADP+
2° Adh, ethanol as substrate
Thermoanaerobacter ethanolicus
0.094
-
NADPH
1°Adh, acetaldehyde as substrate
Thermoanaerobacter ethanolicus
0.096
-
NAD+
1° Adh, ethanol as substrate
Thermoanaerobacter ethanolicus
0.16
-
propanone
2° Adh
Thermoanaerobacter ethanolicus
0.24
-
Butanone
2° Adh
Thermoanaerobacter ethanolicus
0.25
-
acetaldehyde
1° Adh
Thermoanaerobacter ethanolicus
0.44
-
Butanal
1° Adh
Thermoanaerobacter ethanolicus
0.5
-
acetylCoA
2° Adh
Thermoanaerobacter ethanolicus
0.51
-
butan-2-ol
2° Adh
Thermoanaerobacter ethanolicus
0.56
-
propan-2-ol
2° Adh
Thermoanaerobacter ethanolicus
1.6
-
formaldehyde
1° Adh
Thermoanaerobacter ethanolicus
2.1
-
acetaldehyde
2° Adh
Thermoanaerobacter ethanolicus
2.9
-
Butanal
2° Adh
Thermoanaerobacter ethanolicus
10
-
butan-1-ol
2° Adh
Thermoanaerobacter ethanolicus
19
-
n-Propanol
2° Adh
Thermoanaerobacter ethanolicus
23
-
n-Propanol
1° Adh
Thermoanaerobacter ethanolicus
25
-
ethanol
1° Adh
Thermoanaerobacter ethanolicus
34
-
n-butanol
1° Adh
Thermoanaerobacter ethanolicus
66
-
ethanol
2° Adh
Thermoanaerobacter ethanolicus
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
40000
-
4 * 40000, 2° Adh, secondary-alcohol dehydrogenase, SDS-PAGE
Thermoanaerobacter ethanolicus
42000
-
4 * 42000, 2° Adh, secondary alcohol dehydrogenase, SDS-PAGE
Thermoanaerobacter ethanolicus
96000
-
-
Clostridium acetobutylicum
96000
-
-
Escherichia coli
160000
-
2° Adh, gel filtration
Thermoanaerobacter ethanolicus
170000
-
1° Adh, primary-alcohol dehydrogenase, gel filtration
Thermoanaerobacter ethanolicus
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Clostridium acetobutylicum
-
NRRL B643
-
Clostridium acetobutylicum NRRL B643
-
NRRL B643
-
Clostridium beijerinckii
-
NRRL B592
-
Clostridium beijerinckii NRRL B592
-
NRRL B592
-
Clostridium kluyveri
-
-
-
Escherichia coli
-
-
-
Leuconostoc mesenteroides
-
-
-
Propionibacterium freudenreichii
-
-
-
Ruminiclostridium thermocellum
-
-
-
Saccharomyces cerevisiae
-
yeast
-
Thermoanaerobacter brockii
-
-
-
Thermoanaerobacter ethanolicus
-
39E(A.T.C.C. 33223), formerly Clostridium thermohydrosulfuricum 39E; strain JW200
-
Thermoanaerobacter ethanolicus JW 200
-
strain JW200
-
Thermoanaerobacter thermohydrosulfuricus
-
new name Thermoanaerobacter ethanolicus strain 39 E
-
Vibrio harveyi
-
-
-
Zymomonas mobilis
-
-
-
Purification (Commentary)
Commentary
Organism
1° Adh and 2°Adh
Thermoanaerobacter ethanolicus
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
69
-
2° Adh
Thermoanaerobacter ethanolicus
140
-
1° Adh
Thermoanaerobacter ethanolicus
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-butanol + NADP+
-
286197
Thermoanaerobacter brockii
butan-2-one + NADPH
-
-
-
r
2-butanol + NADP+
2° Adh
286197
Thermoanaerobacter ethanolicus
butan-2-one + NADPH
-
-
-
r
acetaldehyde + NADPH + H+
-
286197
Thermoanaerobacter ethanolicus
ethanol + NADP+
-
-
-
?
acetaldehyde + NADPH + H+
-
286197
Thermoanaerobacter ethanolicus 39E
ethanol + NADP+
-
-
-
?
acetaldehyde + NADPH + H+
-
286197
Thermoanaerobacter ethanolicus JW 200
ethanol + NADP+
-
-
-
?
acetyl-CoA + NADPH
-
286197
Thermoanaerobacter ethanolicus
acetaldehyde + CoA + NADP+
-
-
-
?
ethanol + NADP+
-
286197
Escherichia coli
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Saccharomyces cerevisiae
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Vibrio harveyi
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Leuconostoc mesenteroides
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Zymomonas mobilis
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Thermoanaerobacter thermohydrosulfuricus
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Clostridium kluyveri
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Propionibacterium freudenreichii
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Clostridium beijerinckii
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Clostridium acetobutylicum
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Thermoanaerobacter ethanolicus
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Ruminiclostridium thermocellum
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Thermoanaerobacter brockii
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Clostridium acetobutylicum NRRL B643
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Thermoanaerobacter ethanolicus 39E
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Clostridium beijerinckii NRRL B592
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Thermoanaerobacter ethanolicus JW 200
acetaldehyde + NADPH + H+
-
-
-
r
formaldehyde + NADPH
-
286197
Thermoanaerobacter ethanolicus
methanol + NADP+
-
-
-
?
formaldehyde + NADPH
-
286197
Thermoanaerobacter ethanolicus 39E
methanol + NADP+
-
-
-
?
formaldehyde + NADPH
-
286197
Thermoanaerobacter ethanolicus JW 200
methanol + NADP+
-
-
-
?
additional information
1° Adh specific for 1°alcohols and aldehydes, no detectable actvity towards ketones, 2°alcohols or acetyl-CoA
286197
Thermoanaerobacter ethanolicus
?
-
-
-
-
additional information
1° Adh specific for 1°alcohols and aldehydes, no detectable actvity towards ketones, 2°alcohols or acetyl-CoA
286197
Thermoanaerobacter ethanolicus 39E
?
-
-
-
-
additional information
1° Adh specific for 1°alcohols and aldehydes, no detectable actvity towards ketones, 2°alcohols or acetyl-CoA
286197
Thermoanaerobacter ethanolicus JW 200
?
-
-
-
-
n-butanol + NADP+
-
286197
Zymomonas mobilis
butyraldehyde + NADPH
-
-
-
r
n-butanol + NADP+
-
286197
Thermoanaerobacter ethanolicus
butyraldehyde + NADPH
-
-
-
r
n-butyraldehyde + NADPH
-
286197
Thermoanaerobacter ethanolicus
n-butanol + NADP+
-
-
-
r
n-butyraldehyde + NADPH
-
286197
Thermoanaerobacter ethanolicus 39E
n-butanol + NADP+
-
-
-
r
n-butyraldehyde + NADPH
-
286197
Thermoanaerobacter ethanolicus JW 200
n-butanol + NADP+
-
-
-
r
n-propanol + NADP+
-
286197
Thermoanaerobacter ethanolicus
propionaldehyde + NADPH
-
-
-
r
propan-2-ol + NADP+
2° Adh
286197
Thermoanaerobacter ethanolicus
propanone + NADPH
-
-
-
r
Subunits
Subunits
Commentary
Organism
tetramer
-
Propionibacterium freudenreichii
tetramer
4 * 40000, 2° Adh, secondary-alcohol dehydrogenase, SDS-PAGE; 4 * 42000, 2° Adh, secondary alcohol dehydrogenase, SDS-PAGE
Thermoanaerobacter ethanolicus
tetramer
-
Thermoanaerobacter brockii
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.5
9
NAD(P)+ reduction
Thermoanaerobacter ethanolicus
7
-
aldehyde-reduction
Thermoanaerobacter ethanolicus
9
-
alcohol-oxidation
Thermoanaerobacter ethanolicus
Application (protein specific)
Application
Commentary
Organism
synthesis
industrial ethanol production
Saccharomyces cerevisiae
synthesis
industrial ethanol production; potential use for industrial production of ethanol by fermentation, thermophilic fermentations offer the potential to separate ethanol from continous cultures at process temperature and reduced pressure during growth
Thermoanaerobacter ethanolicus
synthesis
industrial ethanol production
Zymomonas mobilis
Cloned(Commentary) (protein specific)
Commentary
Organism
1° Adh cloned and characterized
Clostridium acetobutylicum
1° Adh cloned and characterized
Escherichia coli
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.02
-
NADP+
1° Adh, ethanol as substrate
Thermoanaerobacter ethanolicus
0.025
-
NADH
1° Adh, acetaldehyde as substrate
Thermoanaerobacter ethanolicus
0.033
-
NADPH
2° Adh, propanone as substrate
Thermoanaerobacter ethanolicus
0.049
-
NADP+
2° Adh, butan-2-ol as substrate
Thermoanaerobacter ethanolicus
0.055
-
NADPH
2° Adh, acetaldehyde as substrate
Thermoanaerobacter ethanolicus
0.07
-
NADP+
2° Adh, ethanol as substrate
Thermoanaerobacter ethanolicus
0.094
-
NADPH
1°Adh, acetaldehyde as substrate
Thermoanaerobacter ethanolicus
0.096
-
NAD+
1° Adh, ethanol as substrate
Thermoanaerobacter ethanolicus
0.16
-
propanone
2° Adh
Thermoanaerobacter ethanolicus
0.24
-
Butanone
2° Adh
Thermoanaerobacter ethanolicus
0.25
-
acetaldehyde
1° Adh
Thermoanaerobacter ethanolicus
0.44
-
Butanal
1° Adh
Thermoanaerobacter ethanolicus
0.5
-
acetylCoA
2° Adh
Thermoanaerobacter ethanolicus
0.51
-
butan-2-ol
2° Adh
Thermoanaerobacter ethanolicus
0.56
-
propan-2-ol
2° Adh
Thermoanaerobacter ethanolicus
1.6
-
formaldehyde
1° Adh
Thermoanaerobacter ethanolicus
2.1
-
acetaldehyde
2° Adh
Thermoanaerobacter ethanolicus
2.9
-
Butanal
2° Adh
Thermoanaerobacter ethanolicus
10
-
butan-1-ol
2° Adh
Thermoanaerobacter ethanolicus
19
-
n-Propanol
2° Adh
Thermoanaerobacter ethanolicus
23
-
n-Propanol
1° Adh
Thermoanaerobacter ethanolicus
25
-
ethanol
1° Adh
Thermoanaerobacter ethanolicus
34
-
n-butanol
1° Adh
Thermoanaerobacter ethanolicus
66
-
ethanol
2° Adh
Thermoanaerobacter ethanolicus
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
40000
-
4 * 40000, 2° Adh, secondary-alcohol dehydrogenase, SDS-PAGE
Thermoanaerobacter ethanolicus
42000
-
4 * 42000, 2° Adh, secondary alcohol dehydrogenase, SDS-PAGE
Thermoanaerobacter ethanolicus
96000
-
-
Clostridium acetobutylicum
96000
-
-
Escherichia coli
160000
-
2° Adh, gel filtration
Thermoanaerobacter ethanolicus
170000
-
1° Adh, primary-alcohol dehydrogenase, gel filtration
Thermoanaerobacter ethanolicus
Purification (Commentary) (protein specific)
Commentary
Organism
1° Adh and 2°Adh
Thermoanaerobacter ethanolicus
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
69
-
2° Adh
Thermoanaerobacter ethanolicus
140
-
1° Adh
Thermoanaerobacter ethanolicus
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2-butanol + NADP+
-
286197
Thermoanaerobacter brockii
butan-2-one + NADPH
-
-
-
r
2-butanol + NADP+
2° Adh
286197
Thermoanaerobacter ethanolicus
butan-2-one + NADPH
-
-
-
r
acetaldehyde + NADPH + H+
-
286197
Thermoanaerobacter ethanolicus
ethanol + NADP+
-
-
-
?
acetaldehyde + NADPH + H+
-
286197
Thermoanaerobacter ethanolicus 39E
ethanol + NADP+
-
-
-
?
acetaldehyde + NADPH + H+
-
286197
Thermoanaerobacter ethanolicus JW 200
ethanol + NADP+
-
-
-
?
acetyl-CoA + NADPH
-
286197
Thermoanaerobacter ethanolicus
acetaldehyde + CoA + NADP+
-
-
-
?
ethanol + NADP+
-
286197
Escherichia coli
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Saccharomyces cerevisiae
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Vibrio harveyi
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Leuconostoc mesenteroides
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Zymomonas mobilis
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Thermoanaerobacter thermohydrosulfuricus
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Clostridium kluyveri
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Propionibacterium freudenreichii
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Clostridium beijerinckii
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Clostridium acetobutylicum
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Thermoanaerobacter ethanolicus
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Ruminiclostridium thermocellum
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Thermoanaerobacter brockii
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Clostridium acetobutylicum NRRL B643
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Thermoanaerobacter ethanolicus 39E
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Clostridium beijerinckii NRRL B592
acetaldehyde + NADPH + H+
-
-
-
r
ethanol + NADP+
-
286197
Thermoanaerobacter ethanolicus JW 200
acetaldehyde + NADPH + H+
-
-
-
r
formaldehyde + NADPH
-
286197
Thermoanaerobacter ethanolicus
methanol + NADP+
-
-
-
?
formaldehyde + NADPH
-
286197
Thermoanaerobacter ethanolicus 39E
methanol + NADP+
-
-
-
?
formaldehyde + NADPH
-
286197
Thermoanaerobacter ethanolicus JW 200
methanol + NADP+
-
-
-
?
additional information
1° Adh specific for 1°alcohols and aldehydes, no detectable actvity towards ketones, 2°alcohols or acetyl-CoA
286197
Thermoanaerobacter ethanolicus
?
-
-
-
-
additional information
1° Adh specific for 1°alcohols and aldehydes, no detectable actvity towards ketones, 2°alcohols or acetyl-CoA
286197
Thermoanaerobacter ethanolicus 39E
?
-
-
-
-
additional information
1° Adh specific for 1°alcohols and aldehydes, no detectable actvity towards ketones, 2°alcohols or acetyl-CoA
286197
Thermoanaerobacter ethanolicus JW 200
?
-
-
-
-
n-butanol + NADP+
-
286197
Zymomonas mobilis
butyraldehyde + NADPH
-
-
-
r
n-butanol + NADP+
-
286197
Thermoanaerobacter ethanolicus
butyraldehyde + NADPH
-
-
-
r
n-butyraldehyde + NADPH
-
286197
Thermoanaerobacter ethanolicus
n-butanol + NADP+
-
-
-
r
n-butyraldehyde + NADPH
-
286197
Thermoanaerobacter ethanolicus 39E
n-butanol + NADP+
-
-
-
r
n-butyraldehyde + NADPH
-
286197
Thermoanaerobacter ethanolicus JW 200
n-butanol + NADP+
-
-
-
r
n-propanol + NADP+
-
286197
Thermoanaerobacter ethanolicus
propionaldehyde + NADPH
-
-
-
r
propan-2-ol + NADP+
2° Adh
286197
Thermoanaerobacter ethanolicus
propanone + NADPH
-
-
-
r
Subunits (protein specific)
Subunits
Commentary
Organism
tetramer
-
Propionibacterium freudenreichii
tetramer
4 * 40000, 2° Adh, secondary-alcohol dehydrogenase, SDS-PAGE; 4 * 42000, 2° Adh, secondary alcohol dehydrogenase, SDS-PAGE
Thermoanaerobacter ethanolicus
tetramer
-
Thermoanaerobacter brockii
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
6.5
9
NAD(P)+ reduction
Thermoanaerobacter ethanolicus
7
-
aldehyde-reduction
Thermoanaerobacter ethanolicus
9
-
alcohol-oxidation
Thermoanaerobacter ethanolicus
Other publictions for EC 1.1.1.2
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
737853
Choi
Enhancing biomass and ethanol ...
Escherichia coli
Biores. Technol.
213
54-57
2016
-
1
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
737874
Takeda
An enantioselective NADP(+)-de ...
Mycobacterium sp., Mycobacterium sp. B-009
Biosci. Biotechnol. Biochem.
80
1155-1163
2016
-
-
-
-
-
-
3
4
1
1
1
-
-
2
-
-
-
-
-
-
-
-
6
1
1
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1
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Degradation of swainsonine by ...
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Chung
Expression of a heat-stable NA ...
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Design and synthesis of potent ...
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737164
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Single gene insertion drives b ...
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Elleuche
Group III alcohol dehydrogenas ...
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1
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2
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Alsafadi
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728605
Vitale
Physicochemical characterizati ...
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737531
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Alcohol dehydrogenases from Sc ...
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2013
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Bezsudnova
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Ausili
Alcohol dehydrogenase from the ...
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Ying
Characterization of a zinc-con ...
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Breicha
Crystallization and preliminar ...
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Carbone
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Expression, purification and c ...
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Quynh
Aliphatic aldehyde reductase a ...
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Ying
Molecular characterization of ...
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A novel NADPH-dependent aldehy ...
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Vidal
Characterization of an alcohol ...
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Carbone
Structure of aldehyde reductas ...
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Machielsen
Laboratory evolution of Pyroco ...
Pyrococcus furiosus
Extremophiles
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7
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12
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1
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1
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42
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5
1
2
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1
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1
1
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7
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12
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1
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1
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42
-
5
1
2
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735529
Asako
Engineering of NADPH-dependent ...
Penicillium citrinum, Penicillium citrinum IFO 4631
Appl. Microbiol. Biotechnol.
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2008
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4
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5
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4
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3
-
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-
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2
2
684751
Ying
Purification and characterizat ...
Pseudothermotoga hypogea
Arch. Microbiol.
187
499-510
2007
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6
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1
2
1
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1
1
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1
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1
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15
1
1
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1
6
2
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6
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1
2
1
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1
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1
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1
-
15
1
1
-
1
6
2
-
-
-
-
-
-
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-
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735567
Inokuma
Characterization of enzymes in ...
Moorella sp., Moorella sp. HUC22-1
Arch. Microbiol.
188
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2007
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1
1
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3
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2
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5
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1
1
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5
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13
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1
2
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2
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668040
Fossati
Exploitation of the alcohol de ...
Lactobacillus brevis, Thermoanaerobacter brockii
Biotechnol. Bioeng.
93
1216-1220
2006
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2
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2
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4
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2
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2
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2
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2
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2
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2
2
-
2
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2
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677193
Short
Metabolism of trans, trans-muc ...
Mus musculus
Toxicol. Appl. Pharmacol.
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2006
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1
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1
1
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2
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2
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1
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1
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1
1
1
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2
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1
-
1
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736940
Munir
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Separation and properties of t ...
Euglena gracilis, Euglena gracilis Z
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2743-2747
2006
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8
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8
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15
-
2
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2
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667168
Barski
Developmental expression and f ...
Mus musculus, Mus musculus C57BL/6
Am. J. Physiol. Renal Physiol.
289
F200-F207
2005
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1
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2
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1
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8
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1
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1
1
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1
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1
1
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5
1
-
8
-
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1
1
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668054
Findrik
Kinetic modeling of acetopheno ...
Thermoanaerobacter sp.
Biotechnol. Lett.
27
1087-1095
2005
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1
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6
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6
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2
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669787
El-Kabbani
Structure of aldehyde reductas ...
Sus scrofa
J. Med. Chem.
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5536-5542
2005
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1
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2
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1
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1
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1
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671506
Ernst
Enatioselective reduction of c ...
Lactobacillus brevis
Appl. Microbiol. Biotechnol.
66
629-634
2005
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1
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1
2
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4
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2
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1
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672042
Schracke
Synthesis of linear gramicidin ...
Brevibacillus brevis
Biochemistry
44
8507-8513
2005
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1
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-
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1
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1
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19
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2
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1
2
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1
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19
-
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672730
Liu
Asymmetric reduction of ethyl ...
Sporidiobolus salmonicolor, Sporidiobolus salmonicolor ZJU0307
Biotechnol. Lett.
27
119-125
2005
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1
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3
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1
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1
1
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3
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2
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1
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675283
Petroval
Factorizing selectivity determ ...
Sus scrofa
J. Med. Chem.
48
5659-5665
2005
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-
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1
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675348
Schlieben
Atomic resolution of R-specifi ...
Lactobacillus brevis
J. Mol. Biol.
349
801-813
2005
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1
1
1
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10
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1
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2
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1
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10
1
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4
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1
4
1
1
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10
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2
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1
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10
1
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-
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676759
Jing
Efficient production of recomb ...
Sporidiobolus salmonicolor, Sporidiobolus salmonicolor ZJUB 105
Prep. Biochem. Biotechnol.
35
203-215
2005
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1
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4
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1
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1
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1
1
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1
-
2
-
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-
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654908
Brisdelli
Kinetic properties of native a ...
Kluyveromyces lactis
Biochimie
86
705-712
2004
-
-
-
-
-
-
-
23
1
-
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1
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19
-
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23
1
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19
-
-
-
-
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-
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655106
Weckbecker
Improved synthesis of chiral a ...
Lactobacillus kefiri
Biotechnol. Lett.
26
1739-1744
2004
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1
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-
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1
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1
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656549
Sulzenbacher
Crystal structure of E. coli a ...
Escherichia coli
J. Mol. Biol.
342
489-502
2004
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1
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1
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1
1
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1
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1
1
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1
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-
1
1
-
-
-
-
-
-
-
-
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654084
Valencia
Crystallization and preliminar ...
Pelophylax perezi, Saccharomyces cerevisiae
Acta Crystallogr. Sect. D
59
334-337
2003
-
-
-
2
-
-
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5
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2
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2
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-
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654354
King
Thermodynamics of the reductio ...
Thermoanaerobacter brockii
Arch. Biochem. Biophys.
410
280-286
2003
-
-
-
-
-
-
-
-
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1
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1
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1
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1
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656514
Niefind
The crystal structure of R-spe ...
Lactobacillus brevis
J. Mol. Biol.
327
317-328
2003
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1
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1
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1
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2
1
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1
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1
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1
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-
-
-
2
1
-
-
-
-
-
-
-
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656524
Rosell
Crystal structure of the verte ...
Pelophylax perezi
J. Mol. Biol.
330
75-85
2003
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1
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1
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-
-
-
-
-
-
-
-
-
-
-
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657019
Montesano
A novel potato defence-related ...
Solanum tuberosum
Plant Mol. Biol.
52
177-189
2003
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-
-
-
-
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6
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7
-
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2
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6
-
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-
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7
-
-
-
-
-
2
-
-
-
-
-
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654065
Shimon
Thermophilic alcohol dehydroge ...
Entamoeba histolytica
Acta Crystallogr. Sect. D
58
546-548
2002
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-
-
1
-
-
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1
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1
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1
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-
-
1
-
-
-
-
-
-
-
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654493
Larroy
Characterization of the Saccha ...
Saccharomyces cerevisiae
Biochem. J.
361
163-172
2002
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1
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3
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2
1
66
1
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18
1
1
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2
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1
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22
-
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3
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1
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2
1
66
1
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-
18
1
1
-
2
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655264
Munir
Occurrence of a novel NADP(+)- ...
Euglena gracilis
Comp. Biochem. Physiol. B
132
535-540
2002
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2
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1
4
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2
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1
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2
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1
4
-
-
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2
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1
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286211
Galamba
Molecular and biochemical char ...
Bacillus subtilis, Equus sp., Escherichia coli, Helicobacter pylori, Mycobacterium avium, Mycobacterium avium subsp. paratuberculosis, Mycobacterium bovis, Mycobacterium leprae, Mycobacterium smegmatis, Mycobacterium tuberculosis
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1
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5
2
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5
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2
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2
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1
1
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10
1
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286212
Ye
Crystal structure of an aldehy ...
Sus scrofa
Proteins
44
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2001
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1
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1
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1
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722173
van der Oost
Genetic and biochemical charac ...
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6
1
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4
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1
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2
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1
2
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4
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3
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1
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1
6
1
2
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4
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2
1
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2
2
286210
Tani
Thermostable NADP(+)-dependent ...
Acinetobacter calcoaceticus, Acinetobacter sp., Acinetobacter sp. M-1
Appl. Environ. Microbiol.
66
5231-5235
2000
1
1
1
-
-
1
10
-
-
-
2
-
-
4
-
-
2
-
-
-
2
-
36
1
-
-
1
-
2
-
1
-
-
-
-
1
1
1
-
-
-
1
-
10
-
-
-
-
2
-
-
-
-
2
-
-
2
-
36
1
-
-
1
-
2
-
1
-
-
-
-
-
-
-
286150
Shinoda
Inhibition of human aldehyde r ...
Homo sapiens, Sus scrofa
Biol. Pharm. Bull.
22
741-744
1999
-
2
-
-
-
-
13
-
-
-
-
2
-
2
-
-
-
-
-
4
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
13
-
-
-
-
-
2
-
-
-
-
-
4
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286205
Colrat
Purification and characterizat ...
Thermococcus sp., Vigna radiata
Plant Physiol.
119
621-626
1999
-
1
-
-
-
-
-
23
-
-
2
1
-
6
-
-
-
-
-
-
1
-
25
2
-
-
-
-
-
1
-
2
-
-
-
-
1
-
2
-
-
-
-
-
-
23
-
-
2
1
-
-
-
-
-
-
1
-
25
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
286206
Peralba
Structural and enzymatic prope ...
Clostridium beijerinckii, Entamoeba histolytica, Pelophylax perezi, Thermoanaerobacter brockii, Thermoanaerobacter ethanolicus
J. Biol. Chem.
274
26021-26026
1999
-
-
1
-
-
-
-
29
-
-
2
-
-
5
-
-
1
-
-
2
-
-
28
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
29
-
-
2
-
-
-
-
1
-
2
-
-
28
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286207
Antoine
Cloning and over-expression in ...
Aquifex aeolicus, Archaeoglobus fulgidus, Bacillus methanolicus, Clostridium acetobutylicum, Pyrococcus furiosus, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Thermococcus hydrothermalis, Thermococcus litoralis, Thermococcus zilligii, Zymomonas mobilis
Eur. J. Biochem.
264
880-889
1999
-
-
2
-
-
-
-
4
-
-
3
-
-
11
-
-
2
-
-
-
2
-
4
4
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
4
-
-
3
-
-
-
-
2
-
-
2
-
4
4
-
-
-
-
2
-
-
-
-
-
-
-
-
-
286209
Li
Crystal structure of a thermop ...
Thermoanaerobacter brockii
Proteins
37
619-627
1999
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
722498
Ma
An unusual oxygen-sensitive, i ...
Pyrococcus furiosus
J. Bacteriol.
181
1163-1170
1999
-
-
-
-
-
-
-
7
1
2
3
1
-
1
1
-
1
-
-
-
1
-
14
1
1
-
3
7
1
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
7
1
2
3
1
-
1
-
1
-
-
1
-
14
1
1
-
3
7
1
-
-
-
-
1
1
-
7
7
286204
Udovikova
Mitochondrial aldehyde reducta ...
Rattus norvegicus
Int. J. Biochem. Cell Biol.
30
597-608
1998
-
-
-
-
-
-
3
1
2
-
-
2
-
3
-
-
-
-
-
3
-
-
4
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
1
2
-
-
2
-
-
-
-
-
3
-
-
4
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
286201
Bogin
Thermoanaerobacter brockii alc ...
Equus sp., Homo sapiens, Saccharomyces cerevisiae, Thermoanaerobacter brockii
Protein Sci.
6
450-458
1997
-
-
1
3
-
-
-
7
-
-
-
-
-
4
-
-
1
-
-
2
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
-
-
-
-
7
-
-
-
-
-
-
-
1
-
2
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286202
Li
Purification and sequence anal ...
Bacillus methanolicus, Clostridium acetobutylicum, Drosophila melanogaster, Escherichia coli, Saccharomyces cerevisiae, Thermococcus sp., Thermococcus sp. AN1, Zymomonas mobilis
J. Bacteriol.
179
4433-4437
1997
-
-
1
-
-
-
-
6
-
-
2
-
-
12
-
-
1
-
-
-
1
1
17
1
1
-
1
-
1
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
6
-
-
2
-
-
-
-
1
-
-
1
1
17
1
1
-
1
-
1
-
-
-
-
-
-
-
-
-
286203
Van Iersel
Purification and characterizat ...
Acinetobacter calcoaceticus, Saccharomyces cerevisiae
Appl. Environ. Microbiol.
63
4079-4082
1997
-
-
-
-
-
-
-
17
-
-
1
-
-
2
-
-
2
-
-
-
1
-
9
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
17
-
-
1
-
-
-
-
2
-
-
1
-
9
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286200
Barski
The C-terminal loop of aldehyd ...
Homo sapiens
Biochemistry
35
14276-14280
1996
-
-
-
1
-
-
8
15
1
-
1
2
-
2
-
-
1
-
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
8
-
15
1
-
1
2
-
-
-
1
-
-
-
-
5
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286199
Barski
Mechanism of human aldehyde re ...
Homo sapiens
Biochemistry
34
11264-11275
1995
-
-
-
-
-
-
6
24
-
-
-
4
-
3
-
-
1
-
-
-
-
-
7
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
24
-
-
-
4
-
-
-
1
-
-
-
-
7
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
736339
Ma
Effects of elemental sulfur on ...
Thermococcus paravinellae, Thermococcus paravinellae ES-1
J. Bacteriol.
177
4748-4756
1995
-
-
-
-
-
-
-
6
1
2
2
-
-
2
-
-
-
-
-
-
-
-
16
1
-
-
3
-
-
-
-
2
-
-
-
-
-
-
2
-
-
-
-
-
-
6
1
2
2
-
-
-
-
-
-
-
-
-
16
1
-
-
3
-
-
-
-
-
-
1
1
-
6
6
286197
Burdette
Purification of acetaldehyde d ...
Clostridium acetobutylicum, Clostridium acetobutylicum NRRL B643, Clostridium beijerinckii, Clostridium beijerinckii NRRL B592, Clostridium kluyveri, Escherichia coli, Leuconostoc mesenteroides, Propionibacterium freudenreichii, Ruminiclostridium thermocellum, Saccharomyces cerevisiae, Thermoanaerobacter brockii, Thermoanaerobacter ethanolicus, Thermoanaerobacter ethanolicus JW 200, Thermoanaerobacter thermohydrosulfuricus, Vibrio harveyi, Zymomonas mobilis
Biochem. J.
302
163-170
1994
-
3
2
-
-
-
-
24
-
-
6
-
-
18
-
-
1
-
-
-
2
-
36
3
-
-
-
-
3
-
-
-
-
-
-
-
3
2
-
-
-
-
-
-
-
24
-
-
6
-
-
-
-
1
-
-
2
-
36
3
-
-
-
-
3
-
-
-
-
-
-
-
-
-
286198
Ma
Purification and characterizat ...
Acetobacter aceti, Drosophila melanogaster, Methanobacterium palustre, Methanoculleus thermophilus, Methanofollis liminatans, Saccharomyces cerevisiae, Thermoanaerobacter brockii, Thermococcus litoralis, Zymomonas mobilis
Appl. Environ. Microbiol.
60
562-568
1994
1
-
-
-
-
-
3
4
-
-
3
-
-
9
-
-
2
-
-
-
1
2
15
4
1
-
3
-
1
-
-
1
-
-
-
1
-
-
1
-
-
-
-
3
-
4
-
-
3
-
-
-
-
2
-
-
1
2
15
4
1
-
3
-
1
-
-
-
-
-
-
-
-
-
286149
Bhatnagar
Human liver aldehyde reductase ...
Homo sapiens
Arch. Biochem. Biophys.
287
329-336
1991
-
1
-
-
-
-
3
-
-
-
-
4
-
1
-
-
-
-
-
1
-
-
7
1
-
-
-
-
1
-
-
1
-
-
-
-
1
-
1
-
-
-
-
3
-
-
-
-
-
4
-
-
-
-
-
1
-
-
7
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
286196
Ohta
Localization, isolation and pr ...
Bos taurus, Canis lupus familiaris, Cavia porcellus, Homo sapiens, Mus musculus, Oryctolagus cuniculus, Ovis aries, Rattus norvegicus, Sus scrofa
Biochim. Biophys. Acta
1078
395-403
1991
-
-
-
-
-
-
18
9
-
-
1
25
-
10
-
-
1
-
-
9
1
-
42
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
3
-
-
-
-
18
-
9
-
-
1
25
-
-
-
1
-
9
1
-
42
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286221
Tanimoto
Purification and characterizat ...
Homo sapiens
Int. J. Biochem.
23
421-428
1991
-
-
-
-
-
-
1
-
-
-
1
-
-
2
-
-
-
-
-
2
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
2
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286194
Yamada
-
A novel NADPH-dependent aldehy ...
Sporidiobolus salmonicolor, Sporidiobolus salmonicolor AKU 4429
FEMS Microbiol. Lett.
70
45-48
1990
-
1
-
1
-
-
-
9
-
-
1
-
-
2
-
-
1
-
-
-
1
-
17
1
1
-
1
-
1
1
2
1
-
-
-
-
1
-
1
1
-
-
-
-
-
9
-
-
1
-
-
-
-
1
-
-
1
-
17
1
1
-
1
-
1
1
2
-
-
-
-
-
-
-
286192
Kawasaki
Characterization of aldose red ...
Rattus norvegicus
Biochim. Biophys. Acta
996
30-36
1989
-
-
-
-
-
-
8
4
-
-
1
3
-
2
-
-
1
-
-
2
1
-
7
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
8
-
4
-
-
1
3
-
-
-
1
-
2
1
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286193
Arauzo
The NADP-linked aldehyde reduc ...
Crithidia fasciculata, Neurospora crassa, Trypanosoma cruzi
FEMS Microbiol. Lett.
58
283-286
1989
-
-
-
-
-
-
2
9
1
-
-
-
-
4
-
-
2
-
-
2
1
-
11
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
9
1
-
-
-
-
-
-
2
-
2
1
-
11
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
286191
Bryant
-
Purification and properties of ...
Acinetobacter sp., Clostridium beijerinckii, Escherichia coli, Geobacillus stearothermophilus, Saccharomyces cerevisiae, Thermoanaerobacter brockii, Thermoanaerobacter ethanolicus, Thermoanaerobacter thermohydrosulfuricus, Zymomonas mobilis
Appl. Environ. Microbiol.
2
460-465
1988
-
4
-
-
-
-
-
12
-
-
4
-
-
9
-
-
1
-
-
-
-
-
31
3
2
-
4
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
12
-
-
4
-
-
-
-
1
-
-
-
-
31
3
2
-
4
-
-
-
-
-
-
-
-
-
-
-
286220
Das
-
Isolation and characterization ...
Bos taurus
Lens Res.
5
233-247
1988
-
-
-
-
-
-
1
-
-
-
1
-
-
1
-
-
1
-
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
1
-
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
286190
De Jongh
Kinetic mechanism of sheep liv ...
Bos taurus, Ovis aries, Rattus norvegicus
Biochem. J.
242
143-150
1987
-
-
-
-
-
-
9
6
-
-
-
3
-
6
-
-
1
-
-
10
-
-
12
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
9
-
6
-
-
-
3
-
-
-
1
-
10
-
-
12
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286219
Das
-
Purification and properties of ...
Homo sapiens
Lens Res.
4
309-335
1987
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286189
Kovar
Purification of aldehyde reduc ...
Sus scrofa
J. Chromatogr.
351
371-375
1986
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
1
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286218
Worrall
Kinetic studies on the major f ...
Bos taurus
J. Enzyme Inhib.
1
163-168
1986
-
-
-
-
-
-
3
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
288554
Takahashi
Characterization of microsomal ...
Rattus norvegicus
J. Biochem.
99
513-519
1986
-
-
-
-
-
-
-
5
1
-
1
-
-
2
-
-
1
-
-
4
2
-
12
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
5
1
-
1
-
-
-
-
1
-
4
2
-
12
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286186
Das
Purification and properties of ...
Homo sapiens
Arch. Biochem. Biophys.
238
670-679
1985
-
-
-
-
-
-
9
5
-
-
1
3
-
3
-
-
1
-
-
5
-
-
7
1
1
-
1
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
9
-
5
-
-
1
3
-
-
-
1
-
5
-
-
7
1
1
-
1
-
1
-
-
-
-
-
-
-
-
-
286187
Das
Purification and properties of ...
Cavia porcellus, Homo sapiens
Biochim. Biophys. Acta
840
324-333
1985
-
-
-
-
-
-
3
10
-
-
4
6
-
3
-
-
1
-
-
3
-
-
12
2
-
-
-
-
2
-
-
2
-
-
-
-
-
-
2
-
-
-
-
3
-
10
-
-
4
6
-
-
-
1
-
3
-
-
12
2
-
-
-
-
2
-
-
-
-
-
-
-
-
-
286217
Cromlish
Purification and characterizat ...
Sus scrofa
J. Neurochem.
44
1477-1484
1985
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286182
Markus
Tissue distribution of mammali ...
Canis lupus familiaris, Cavia porcellus, Cavia porcellus Hartley, Felis sp., Gallus sp., Homo sapiens, Mus musculus, Mus musculus B10.A, Oryctolagus cuniculus, Ovis aries, Rattus norvegicus, Saimiri, Sus scrofa
Biochem. Med.
29
31-45
1983
-
-
-
-
-
-
-
-
-
-
-
36
-
32
-
-
-
-
-
103
-
-
67
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
36
-
-
-
-
-
103
-
-
67
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286183
Takahashi
Purification and properties of ...
Bos taurus, Cavia porcellus, Rattus norvegicus
Biochim. Biophys. Acta
748
444-452
1983
-
-
-
-
-
-
1
15
2
-
3
3
-
5
-
-
1
-
-
13
3
-
17
2
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
15
2
-
3
3
-
-
-
1
-
13
3
-
17
2
-
-
-
-
1
-
-
-
-
-
-
-
-
-
286184
Hara
Isolation and characterization ...
Bos taurus, Gallus sp., Homo sapiens, Rattus norvegicus
Eur. J. Biochem.
133
207-214
1983
1
-
-
-
-
-
12
32
4
1
9
3
-
5
-
-
1
-
-
17
5
2
51
4
-
-
2
-
4
-
-
-
-
-
-
1
-
-
-
-
-
-
-
12
-
32
4
1
9
3
-
-
-
1
-
17
5
2
51
4
-
-
2
-
4
-
-
-
-
-
-
-
-
-
286185
Magnien
The kinetics and mechanism of ...
Sus scrofa
Eur. J. Biochem.
131
375-381
1983
-
-
-
-
-
-
1
-
-
-
-
1
-
1
-
-
-
-
-
1
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
1
-
-
6
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286176
Sawada
Kinetic mechanisms in the redu ...
Bos taurus, Homo sapiens, Oryctolagus cuniculus, Rattus norvegicus, Sus scrofa
J. Biochem.
92
185-191
1982
-
-
-
-
-
-
3
-
4
-
-
22
-
6
-
-
-
-
-
16
-
-
45
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
4
-
-
22
-
-
-
-
-
16
-
-
45
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286177
Flynn
Aldehyde reductases: Monomeric ...
Cavia porcellus, Drosophila melanogaster, Homo sapiens, Mus musculus, Oryctolagus cuniculus, Rattus norvegicus, Saccharomyces cerevisiae, Sus scrofa
Biochem. Pharmacol.
31
2705-2712
1982
-
3
-
-
-
-
13
-
4
-
14
19
-
8
-
-
2
-
-
20
-
-
40
4
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
13
-
-
4
-
14
19
-
-
-
2
-
20
-
-
40
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286178
Daly
Purification and characterizat ...
Bos taurus, Cavia porcellus, Sus scrofa
Biochem. J.
205
373-380
1982
-
-
-
-
-
-
4
26
1
-
8
11
-
3
-
-
2
-
-
9
2
5
34
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
26
1
-
8
11
-
-
-
2
-
9
2
5
34
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286179
Daly
The kinetic mechanism of the m ...
Bos taurus, Saccharomyces cerevisiae, Sus scrofa
Biochem. J.
205
381-388
1982
-
-
-
-
-
-
6
-
-
-
-
8
-
3
-
-
-
-
-
2
-
-
16
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
8
-
-
-
-
-
2
-
-
16
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286180
Branlant
Properties of an aldose reduct ...
Sus scrofa
Eur. J. Biochem.
129
99-104
1982
-
-
-
-
-
-
3
-
-
-
-
-
-
2
-
-
1
-
-
4
2
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
1
-
4
2
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286181
Petrash
Purification and properties of ...
Bos taurus, Gallus sp., Homo sapiens, Mus musculus, Ovis aries, Rattus norvegicus, Sus scrofa
Biochim. Biophys. Acta
707
105-114
1982
-
3
-
-
-
-
15
40
-
1
9
-
-
9
-
-
2
-
-
31
2
1
45
6
-
-
-
-
5
-
-
-
-
-
-
-
3
-
-
-
-
-
-
15
-
40
-
1
9
-
-
-
-
2
-
31
2
1
45
6
-
-
-
-
5
-
-
-
-
-
-
-
-
-
286216
Lo
Purification and properties of ...
Entamoeba histolytica, Homo sapiens
J. Parasitol.
68
372-377
1982
-
-
-
-
-
-
-
-
-
-
2
-
-
2
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286175
Rivett
Purification of the high-Km al ...
Bos taurus, Cricetinae, Homo sapiens, Mus musculus, Rattus norvegicus
Biochem. J.
197
473-481
1981
-
-
-
-
-
-
2
7
-
-
1
15
-
6
-
-
2
-
-
12
1
2
28
3
-
-
1
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
2
-
7
-
-
1
15
-
-
-
2
-
12
1
2
28
3
-
-
1
-
-
1
1
-
-
-
-
-
-
-
735625
Lamed
Novel NADP-linked alcohol-alde ...
Thermoanaerobacter brockii
Biochem. J.
195
183-190
1981
-
-
-
-
-
-
2
3
-
-
2
-
-
1
-
-
1
-
-
-
-
-
7
1
-
-
1
-
1
1
-
2
-
-
-
-
-
-
2
-
-
-
-
2
-
3
-
-
2
-
-
-
-
1
-
-
-
-
7
1
-
-
1
-
1
1
-
-
-
-
-
-
-
-
286172
Branlant
Purification and some properti ...
Equus sp., Mus musculus, Ovis aries, Rattus norvegicus, Sus scrofa
Eur. J. Biochem.
105
611-621
1980
-
2
-
-
-
-
7
18
-
-
2
12
-
6
-
-
4
-
-
14
1
3
39
2
-
-
-
-
2
-
-
-
-
-
-
-
2
-
-
-
-
-
-
7
-
18
-
-
2
12
-
-
-
4
-
14
1
3
39
2
-
-
-
-
2
-
-
-
-
-
-
-
-
-
286173
Morpeth
Some properties of pig kidney- ...
Homo sapiens, Rattus norvegicus, Sus scrofa
Biochem. J.
191
619-626
1980
-
-
-
-
-
-
1
-
-
-
11
-
-
3
-
-
3
-
-
6
1
2
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
11
-
-
-
-
3
-
6
1
2
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286174
Turner
Isolation and characterization ...
Rattus norvegicus, Sus scrofa
Biochim. Biophys. Acta
613
256-265
1980
2
2
-
-
-
-
13
10
1
-
-
8
-
2
-
-
1
-
-
6
-
-
28
-
-
-
-
-
-
-
-
-
-
-
-
2
2
-
-
-
-
-
-
13
-
10
1
-
-
8
-
-
-
1
-
6
-
-
28
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286215
Cash
Purification from human brain ...
Homo sapiens, Rattus norvegicus
J. Neurochem.
33
1169-1175
1979
-
-
-
-
-
-
-
2
-
-
2
2
-
2
-
-
1
-
-
2
-
-
4
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
2
2
-
-
-
1
-
2
-
-
4
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286169
Hartz
-
Substrate specificity and kine ...
Candida tropicalis, Cucumis melo, Mycobacterium tuberculosis, Neurospora crassa, Penicillium urticae, Phycomyces blakesleeanus, Pseudomonas aeruginosa, Rhizopus oryzae, Saccharomyces cerevisiae, Solanum tuberosum
Mycologia
70
586-593
1978
-
-
-
-
-
-
10
7
-
-
-
-
-
10
-
-
1
-
-
1
-
1
11
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
10
-
7
-
-
-
-
-
-
-
1
-
1
-
1
11
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286170
Davidson
Purification and compositional ...
Drosophila melanogaster, Gallus sp., Homo sapiens, Pecten maximus, Rattus norvegicus, Saccharomyces cerevisiae, Sus scrofa
Biochem. Soc. Trans.
576
940-943
1978
-
-
-
-
-
-
-
-
-
-
13
-
-
7
-
-
4
-
-
6
6
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
13
-
-
-
-
4
-
6
6
-
-
7
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286171
Davidson
Kinetics and mechanism of acti ...
Pecten maximus, Sus scrofa
Biochem. Soc. Trans.
576
943-945
1978
-
-
-
-
-
-
1
-
-
-
-
1
-
2
-
-
-
-
-
1
-
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
1
-
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286168
Wermuth
Purification and properties of ...
Equus sp., Homo sapiens, Pecten maximus, Sus scrofa
J. Biol. Chem.
252
3821-3828
1977
-
-
-
-
-
1
3
10
-
-
7
4
-
5
-
-
1
-
-
15
2
1
28
3
-
-
-
7
2
-
-
-
-
-
-
-
-
-
-
-
-
1
-
3
-
10
-
-
7
4
-
-
-
1
-
15
2
1
28
3
-
-
-
7
2
-
-
-
-
-
-
-
-
-
286214
Reyes
Distribution and properties of ...
Rattus norvegicus
Neurochem. Res.
2
87-97
1977
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286167
Flynn
Properties of the nicotinamide ...
Oryctolagus cuniculus, Sus scrofa
J. Biol. Chem.
250
2933-2940
1975
-
-
-
-
-
1
1
-
-
-
5
6
-
4
-
-
1
-
-
5
1
-
16
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
5
6
-
-
-
1
-
5
1
-
16
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286213
Bronaugh
Partial purification and chara ...
Platyrrhini
J. Neurochem.
21
809-815
1973
-
-
-
-
-
-
2
3
-
-
1
-
-
2
-
-
1
-
-
2
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
3
-
-
1
-
-
-
-
1
-
2
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
286165
Bosron
Triphosphopyridine nucleotide- ...
Bos taurus, Oryctolagus cuniculus, Rattus norvegicus, Sus scrofa
J. Biol. Chem.
217
4480-4485
1972
2
-
-
-
-
-
4
9
-
-
3
12
-
5
-
-
1
-
-
10
1
1
92
3
-
-
-
12
3
-
-
-
-
-
-
2
-
-
-
-
-
-
-
4
-
9
-
-
3
12
-
-
-
1
-
10
1
1
92
3
-
-
-
12
3
-
-
-
-
-
-
-
-
-
286166
Turner
The characterization of two re ...
Bos taurus, Rattus norvegicus, Sus scrofa
Biochem. J.
130
765-772
1972
-
-
-
-
-
-
3
13
-
-
3
-
-
3
-
-
1
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3
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16
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286164
Tabakoff
Purification and characterizat ...
Bos taurus, Oryctolagus cuniculus, Rattus norvegicus
J. Biol. Chem.
245
3263-3268
1970
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